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James Andrew Alspaugh II

Professor of Medicine
Medicine, Infectious Diseases
Duke Box 102359, Durham, NC 27710
DUMC Box 102359, 303 Sands Building, Research Drive, Durham, NC 27710

Overview


The focus of my research is to understand the ways in which microorganisms sense and respond to changes in their environment. As microbial pathogens enter the infected host, dramatic genetic and phenotypic events occur that allow these organisms to survive in this harsh environment. We study the model fungal organism Cryptococcus neoformans to define signal transduction pathways associated with systemic fungal diseases. This pathogenic fungus causes lethal infections of the central nervous …

Current Appointments & Affiliations


Professor of Medicine · 2013 - Present Medicine, Infectious Diseases, Medicine
Professor in Molecular Genetics and Microbiology · 2014 - Present Molecular Genetics and Microbiology, Basic Science Departments
Professor of Cell Biology · 2022 - Present Cell Biology, Basic Science Departments

Education, Training & Certifications


Duke University · 1991 M.D.