Andrew Bradley West | Scholars@Duke

Andrew Bradley West
Consulting Professor in the Department of Pharmacology and Cancer Biology

Current Appointments & Affiliations

Consulting Professor in the Department of Pharmacology and Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 2018

Contact Information

3 Genome Court, MSRB III 5th Fl, DUMC 10385, Durham, NC 27710
MSRB III 5th Floor, DUMC 103853, Durham, NC 27710
andrew.west@duke.edu (919) 684-1656

Background
Education, Training, & Certifications
- Ph.D., Mayo Clinic 2003
Research
Selected Grants
- Mechanisms of LRRK2 Mediated Neurotoxicity awarded by National Institutes of Health 2018 - 2021
- Characterization and functional analysis of PPMI LRRK2 variants awarded by Michael J. Fox Foundation for Parkinson's Research 2018 - 2020
- Efficacies and Pharmacodynamic Assays for LRRk2 Small-Molecule Inhibitors awarded by National Institutes of Health 2018 - 2019
- Innate and Adaptive Immunity in Parkinson Disease; Project 3: PD-linked Genetic Susceptibilities in Macrophage Responses awarded by University of Alabama at Birmingham 2018 - 2019
- Exosome LRRK2 in Predicting Parkinson Disease Phenotypes awarded by National Institutes of Health 2018 - 2019
Publications & Artistic Works
Selected Publications
- Books
  - Moore, DJ, West, AB, Dawson, VL, and Dawson, TM. Molecular pathophysiology of Parkinson's disease. January 2005. Full Text
- Academic Articles
  - Wang, S, and West, AB. "Caught in the act: LRRK2 in exosomes." Biochemical Society Transactions 47, no. 2 (April 2019): 663-670. (Review) Full Text
  - Cresto, N, Gardier, C, Gubinelli, F, Gaillard, M-C, Liot, G, West, AB, and Brouillet, E. "The unlikely partnership between LRRK2 and α-synuclein in Parkinson's disease." The European Journal of Neuroscience 49, no. 3 (February 2019): 339-363. Full Text
  - Kelly, K, Wang, S, Boddu, R, Liu, Z, Moukha-Chafiq, O, Augelli-Szafran, C, and West, AB. "The G2019S mutation in LRRK2 imparts resiliency to kinase inhibition." Experimental Neurology 309 (November 2018): 1-13. Full Text
  - Delic, V, Chandra, S, Abdelmotilib, H, Maltbie, T, Wang, S, Kem, D, Scott, HJ, Underwood, RN, Liu, Z, Volpicelli-Daley, LA, and West, AB. "Sensitivity and specificity of phospho-Ser129 α-synuclein monoclonal antibodies." Journal of Comparative Neurology 526, no. 12 (August 15, 2018): 1978-1990. Full Text
  - Chen-Plotkin, AS, Albin, R, Alcalay, R, Babcock, D, Bajaj, V, Bowman, D, Buko, A, Cedarbaum, J, Chelsky, D, Cookson, MR, Dawson, TM, Dewey, R, Foroud, T, Frasier, M, German, D, Gwinn, K, Huang, X, Kopil, C, Kremer, T, Lasch, S, Marek, K, Marto, JA, Merchant, K, Mollenhauer, B, Naito, A, Potashkin, J, Reimer, A, Rosenthal, LS, Saunders-Pullman, R, Scherzer, CR, Sherer, T, Singleton, A, Sutherland, M, Thiele, I, van der Brug, M, Van Keuren-Jensen, K, Vaillancourt, D, Walt, D, West, A, and Zhang, J. "Finding useful biomarkers for Parkinson's disease." Science Translational Medicine 10, no. 454 (August 2018). (Review) Full Text
  - Liu, Z, Bryant, N, Kumaran, R, Beilina, A, Abeliovich, A, Cookson, MR, and West, AB. "LRRK2 phosphorylates membrane-bound Rabs and is activated by GTP-bound Rab7L1 to promote recruitment to the trans-Golgi network." Human Molecular Genetics 27, no. 2 (January 2018): 385-395. Full Text
  - West, AB. "Achieving neuroprotection with LRRK2 kinase inhibitors in Parkinson disease." Experimental Neurology 298, no. Pt B (December 2017): 236-245. (Review) Full Text
  - Wang, S, Liu, Z, Ye, T, Mabrouk, OS, Maltbie, T, Aasly, J, and West, AB. "Elevated LRRK2 autophosphorylation in brain-derived and peripheral exosomes in LRRK2 mutation carriers." Acta Neuropathologica Communications 5, no. 1 (November 22, 2017): 86-null. Full Text
  - Harms, AS, Delic, V, Thome, AD, Bryant, N, Liu, Z, Chandra, S, Jurkuvenaite, A, and West, AB. "α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration." Acta Neuropathologica Communications 5, no. 1 (November 21, 2017): 85-null. Full Text
  - Abdelmotilib, H, and West, AB. "Breathing new life into an old target: pulmonary disease drugs for Parkinson's disease therapy." Genome Medicine 9, no. 1 (October 19, 2017): 88-null. Full Text
  - Abdelmotilib, H, Maltbie, T, Delic, V, Liu, Z, Hu, X, Fraser, KB, Moehle, MS, Stoyka, L, Anabtawi, N, Krendelchtchikova, V, Volpicelli-Daley, LA, and West, A. "α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration." Neurobiology of Disease 105 (September 2017): 84-98. Full Text
  - Zhao, HT, John, N, Delic, V, Ikeda-Lee, K, Kim, A, Weihofen, A, Swayze, EE, Kordasiewicz, HB, West, AB, and Volpicelli-Daley, LA. "LRRK2 Antisense Oligonucleotides Ameliorate α-Synuclein Inclusion Formation in a Parkinson's Disease Mouse Model." Molecular Therapy. Nucleic Acids 8 (September 2017): 508-519. Full Text
  - Ivanova, AA, Caspary, T, Seyfried, NT, Duong, DM, West, AB, Liu, Z, and Kahn, RA. "Biochemical characterization of purified mammalian ARL13B protein indicates that it is an atypical GTPase and ARL3 guanine nucleotide exchange factor (GEF)." The Journal of Biological Chemistry 292, no. 26 (June 2017): 11091-11108. Full Text
  - Gwinn, K, David, KK, Swanson-Fischer, C, Albin, R, Hillaire-Clarke, CS, Sieber, B-A, Lungu, C, Bowman, FD, Alcalay, RN, Babcock, D, Dawson, TM, Dewey, RB, Foroud, T, German, D, Huang, X, Petyuk, V, Potashkin, JA, Saunders-Pullman, R, Sutherland, M, Walt, DR, West, AB, Zhang, J, Chen-Plotkin, A, Scherzer, CR, Vaillancourt, DE, and Rosenthal, LS. "Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program." Biomarkers in Medicine 11, no. 6 (May 2017): 451-473. Full Text
  - Liu, Z, and West, AB. "The dual enzyme LRRK2 hydrolyzes GTP in both its GTPase and kinase domains in vitro." Biochimica Et Biophysica Acta. Proteins and Proteomics 1865, no. 3 (March 2017): 274-280. Full Text
  - Ellis, SE, Gupta, S, Moes, A, West, AB, and Arking, DE. "Exaggerated CpH methylation in the autism-affected brain." Molecular Autism 8 (January 2017): 6-null. Full Text
  - Ma, Z, Xia, W, Liu, F, Ma, J, Sun, S, Zhang, J, Jiang, N, Wang, X, Hu, J, and Ma, D. "SLC44A4 mutation causes autosomal dominant hereditary postlingual non-syndromic mid-frequency hearing loss." Human Molecular Genetics 26, no. 2 (January 2017): 383-394. Full Text
  - Fraser, KB, Rawlins, AB, Clark, RG, Alcalay, RN, Standaert, DG, Liu, N, Parkinson's Disease Biomarker Program Consortium, , and West, AB. "Ser(P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease." Movement Disorders : Official Journal of the Movement Disorder Society 31, no. 10 (October 2016): 1543-1550. Full Text
  - West, AB, and Cookson, MR. "Identification of bona-fide LRRK2 kinase substrates." Movement Disorders : Official Journal of the Movement Disorder Society 31, no. 8 (August 2016): 1140-1141. Full Text
  - Volpicelli-Daley, LA, Abdelmotilib, H, Liu, Z, Stoyka, L, Daher, JPL, Milnerwood, AJ, Unni, VK, Hirst, WD, Yue, Z, Zhao, HT, Fraser, K, Kennedy, RE, and West, AB. "G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 36, no. 28 (July 2016): 7415-7427. Full Text
  - Rosenthal, LS, Drake, D, Alcalay, RN, Babcock, D, Bowman, FD, Chen-Plotkin, A, Dawson, TM, Dewey, RB, German, DC, Huang, X, Landin, B, McAuliffe, M, Petyuk, VA, Scherzer, CR, Hillaire-Clarke, CS, Sieber, B-A, Sutherland, M, Tarn, C, West, A, Vaillancourt, D, Zhang, J, Gwinn, K, and PDBP consortium, . "The NINDS Parkinson's disease biomarkers program." Movement Disorders : Official Journal of the Movement Disorder Society 31, no. 6 (June 2016): 915-923. Full Text
  - Ellis, SE, Panitch, R, West, AB, and Arking, DE. "Transcriptome analysis of cortical tissue reveals shared sets of downregulated genes in autism and schizophrenia." Translational Psychiatry 6 (May 24, 2016): e817-null. Full Text
  - Fraser, KB, Moehle, MS, Alcalay, RN, West, AB, and LRRK2 Cohort Consortium, . "Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers." Neurology 86, no. 11 (March 2016): 994-999. Full Text
  - Lavalley, NJ, Slone, SR, Ding, H, West, AB, and Yacoubian, TA. "14-3-3 Proteins regulate mutant LRRK2 kinase activity and neurite shortening." Human Molecular Genetics 25, no. 1 (January 2016): 109-122. Full Text
  - Liu, Z, Mobley, JA, DeLucas, LJ, Kahn, RA, and West, AB. "LRRK2 autophosphorylation enhances its GTPase activity." Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology 30, no. 1 (January 2016): 336-347. Full Text
  - Daher, JPL, Abdelmotilib, HA, Hu, X, Volpicelli-Daley, LA, Moehle, MS, Fraser, KB, Needle, E, Chen, Y, Steyn, SJ, Galatsis, P, Hirst, WD, and West, AB. "Leucine-rich Repeat Kinase 2 (LRRK2) Pharmacological Inhibition Abates α-Synuclein Gene-induced Neurodegeneration." The Journal of Biological Chemistry 290, no. 32 (August 2015): 19433-19444. Full Text
  - Moehle, MS, Daher, JPL, Hull, TD, Boddu, R, Abdelmotilib, HA, Mobley, J, Kannarkat, GT, Tansey, MG, and West, AB. "The G2019S LRRK2 mutation increases myeloid cell chemotactic responses and enhances LRRK2 binding to actin-regulatory proteins." Human Molecular Genetics 24, no. 15 (August 2015): 4250-4267. Full Text
  - Moehle, MS, and West, AB. "M1 and M2 immune activation in Parkinson's Disease: Foe and ally?." Neuroscience 302 (August 2015): 59-73. (Review) Full Text
  - Boddu, R, Hull, TD, Bolisetty, S, Hu, X, Moehle, MS, Daher, JPL, Kamal, AI, Joseph, R, George, JF, Agarwal, A, Curtis, LM, and West, AB. "Leucine-rich repeat kinase 2 deficiency is protective in rhabdomyolysis-induced kidney injury." Human Molecular Genetics 24, no. 14 (July 2015): 4078-4093. Full Text
  - West, AB. "Ten years and counting: moving leucine-rich repeat kinase 2 inhibitors to the clinic." Movement Disorders : Official Journal of the Movement Disorder Society 30, no. 2 (February 2015): 180-189. (Review) Full Text
  - Gupta, S, Ellis, SE, Ashar, FN, Moes, A, Bader, JS, Zhan, J, West, AB, and Arking, DE. "Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism." Nature Communications 5 (December 10, 2014): 5748-null. Full Text
  - Volpicelli-Daley, LA, Gamble, KL, Schultheiss, CE, Riddle, DM, West, AB, and Lee, VM-Y. "Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes." Molecular Biology of the Cell 25, no. 25 (December 2014): 4010-4023. Full Text
  - Liu, Z, Galemmo, RA, Fraser, KB, Moehle, MS, Sen, S, Volpicelli-Daley, LA, DeLucas, LJ, Ross, LJ, Valiyaveettil, J, Moukha-Chafiq, O, Pathak, AK, Ananthan, S, Kezar, H, White, EL, Gupta, V, Maddry, JA, Suto, MJ, and West, AB. "Unique functional and structural properties of the LRRK2 protein ATP-binding pocket." The Journal of Biological Chemistry 289, no. 47 (November 2014): 32937-32951. Full Text
  - Lucas, EK, Dougherty, SE, McMeekin, LJ, Reid, CS, Dobrunz, LE, West, AB, Hablitz, JJ, and Cowell, RM. "PGC-1α provides a transcriptional framework for synchronous neurotransmitter release from parvalbumin-positive interneurons." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 34, no. 43 (October 2014): 14375-14387. Full Text
  - West, AB, Cowell, RM, Daher, JPL, Moehle, MS, Hinkle, KM, Melrose, HL, Standaert, DG, and Volpicelli-Daley, LA. "Differential LRRK2 expression in the cortex, striatum, and substantia nigra in transgenic and nontransgenic rodents." The Journal of Comparative Neurology 522, no. 11 (August 2014): 2465-2480. Full Text
  - Daher, JPL, Volpicelli-Daley, LA, Blackburn, JP, Moehle, MS, and West, AB. "Abrogation of α-synuclein-mediated dopaminergic neurodegeneration in LRRK2-deficient rats." Proceedings of the National Academy of Sciences of the United States of America 111, no. 25 (June 9, 2014): 9289-9294. Full Text
  - Dougherty, SE, Hollimon, JJ, McMeekin, LJ, Bohannon, AS, West, AB, Lesort, M, Hablitz, JJ, and Cowell, RM. "Hyperactivity and cortical disinhibition in mice with restricted expression of mutant huntingtin to parvalbumin-positive cells." Neurobiology of Disease 62 (February 2014): 160-171. Full Text
  - Ellis, SE, Gupta, S, Ashar, FN, Bader, JS, West, AB, and Arking, DE. "RNA-Seq optimization with eQTL gold standards." Bmc Genomics 14 (December 17, 2013): 892-null. Full Text
  - Fraser, KB, Moehle, MS, Daher, JPL, Webber, PJ, Williams, JY, Stewart, CA, Yacoubian, TA, Cowell, RM, Dokland, T, Ye, T, Chen, D, Siegal, GP, Galemmo, RA, Tsika, E, Moore, DJ, Standaert, DG, Kojima, K, Mobley, JA, and West, AB. "LRRK2 secretion in exosomes is regulated by 14-3-3." Human Molecular Genetics 22, no. 24 (December 2013): 4988-5000. Full Text
  - Davies, P, Hinkle, KM, Sukar, NN, Sepulveda, B, Mesias, R, Serrano, G, Alessi, DR, Beach, TG, Benson, DL, White, CL, Cowell, RM, Das, SS, West, AB, and Melrose, HL. "Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies." The Biochemical Journal 453, no. 1 (July 2013): 101-113. Full Text
  - Day, K, Waite, LL, Thalacker-Mercer, A, West, A, Bamman, MM, Brooks, JD, Myers, RM, and Absher, D. "Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape." Genome Biology 14, no. 9 (January 2013): R102-null. Full Text
  - Sampath, S, Bhat, S, Gupta, S, O'Connor, A, West, AB, Arking, DE, and Chakravarti, A. "Defining the contribution of CNTNAP2 to autism susceptibility." Plos One 8, no. 10 (January 2013): e77906-null. Full Text
  - Moehle, MS, Webber, PJ, Tse, T, Sukar, N, Standaert, DG, DeSilva, TM, Cowell, RM, and West, AB. "LRRK2 inhibition attenuates microglial inflammatory responses." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 32, no. 5 (February 2012): 1602-1611. Full Text
  - Stafa, K, Trancikova, A, Webber, PJ, Glauser, L, West, AB, and Moore, DJ. "GTPase activity and neuronal toxicity of Parkinson's disease-associated LRRK2 is regulated by ArfGAP1." Plos Genetics 8, no. 2 (January 2012): e1002526-null. Full Text
  - Trancikova, A, Mamais, A, Webber, PJ, Stafa, K, Tsika, E, Glauser, L, West, AB, Bandopadhyay, R, and Moore, DJ. "Phosphorylation of 4E-BP1 in the mammalian brain is not altered by LRRK2 expression or pathogenic mutations." Plos One 7, no. 10 (January 2012): e47784-null. Full Text
  - Webber, PJ, Smith, AD, Sen, S, Renfrow, MB, Mobley, JA, and West, AB. "Autophosphorylation in the leucine-rich repeat kinase 2 (LRRK2) GTPase domain modifies kinase and GTP-binding activities." Journal of Molecular Biology 412, no. 1 (September 2011): 94-110. Full Text
  - Andrabi, SA, Kang, HC, Haince, J-F, Lee, Y-I, Zhang, J, Chi, Z, West, AB, Koehler, RC, Poirier, GG, Dawson, TM, and Dawson, VL. "Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death." Nature Medicine 17, no. 6 (June 2011): 692-699. Full Text
  - Looyenga, BD, Furge, KA, Dykema, KJ, Koeman, J, Swiatek, PJ, Giordano, TJ, West, AB, Resau, JH, Teh, BT, and MacKeigan, JP. "Chromosomal amplification of leucine-rich repeat kinase-2 (LRRK2) is required for oncogenic MET signaling in papillary renal and thyroid carcinomas." Proceedings of the National Academy of Sciences of the United States of America 108, no. 4 (January 10, 2011): 1439-1444. Full Text
  - Pungaliya, PP, Bai, Y, Lipinski, K, Anand, VS, Sen, S, Brown, EL, Bates, B, Reinhart, PH, West, AB, Hirst, WD, and Braithwaite, SP. "Identification and characterization of a leucine-rich repeat kinase 2 (LRRK2) consensus phosphorylation motif." Plos One 5, no. 10 (October 27, 2010): e13672-null. Full Text
  - Aasly, JO, Vilariño-Güell, C, Dachsel, JC, Webber, PJ, West, AB, Haugarvoll, K, Johansen, KK, Toft, M, Nutt, JG, Payami, H, Kachergus, JM, Lincoln, SJ, Felic, A, Wider, C, Soto-Ortolaza, AI, Cobb, SA, White, LR, Ross, OA, and Farrer, MJ. "Novel pathogenic LRRK2 p.Asn1437His substitution in familial Parkinson's disease." Movement Disorders : Official Journal of the Movement Disorder Society 25, no. 13 (October 2010): 2156-2163. Full Text
  - Lee, BD, Shin, J-H, VanKampen, J, Petrucelli, L, West, AB, Ko, HS, Lee, Y-I, Maguire-Zeiss, KA, Bowers, WJ, Federoff, HJ, Dawson, VL, and Dawson, TM. "Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease." Nature Medicine 16, no. 9 (September 2010): 998-1000. Full Text
  - Sen, S, Webber, PJ, and West, AB. "Dependence of leucine-rich repeat kinase 2 (LRRK2) kinase activity on dimerization." The Journal of Biological Chemistry 284, no. 52 (December 2009): 36346-36356. Full Text
  - Webber, PJ, and West, AB. "LRRK2 in Parkinson's disease: function in cells and neurodegeneration." The Febs Journal 276, no. 22 (November 2009): 6436-6444. (Review) Full Text
  - da Costa, CA, Sunyach, C, Giaime, E, West, A, Corti, O, Brice, A, Safe, S, Abou-Sleiman, PM, Wood, NW, Takahashi, H, Goldberg, MS, Shen, J, and Checler, F. "Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease." Nature Cell Biology 11, no. 11 (November 2009): 1370-1375. Full Text
  - Weiss, LA, Arking, DE, Gene Discovery Project of Johns Hopkins & the Autism Consortium, , Daly, MJ, and Chakravarti, A. "A genome-wide linkage and association scan reveals novel loci for autism." Nature 461, no. 7265 (October 2009): 802-808. Full Text
  - Sen, S, and West, AB. "The therapeutic potential of LRRK2 and alpha-synuclein in Parkinson's disease." Antioxidants & Redox Signaling 11, no. 9 (September 2009): 2167-2187. Full Text
  - Biskup, S, and West, AB. "Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease." Biochimica Et Biophysica Acta 1792, no. 7 (July 2009): 625-633. (Review) Full Text
  - Dawson, TM, Moore, DJ, and West, AB. "Revelations and revolutions in the understanding of Parkinson's disease." Biochimica Et Biophysica Acta 1792, no. 7 (July 2009): 585-586. Full Text
  - Moore, DJ, West, AB, Dikeman, DA, Dawson, VL, and Dawson, TM. "Parkin mediates the degradation-independent ubiquitination of Hsp70." Journal of Neurochemistry 105, no. 5 (June 2008): 1806-1819. Full Text
  - Biskup, S, Moore, DJ, Rea, A, Lorenz-Deperieux, B, Coombes, CE, Dawson, VL, Dawson, TM, and West, AB. "Dynamic and redundant regulation of LRRK2 and LRRK1 expression." Bmc Neuroscience 8 (November 28, 2007): 102-null. Full Text
  - Higashi, S, Biskup, S, West, AB, Trinkaus, D, Dawson, VL, Faull, RLM, Waldvogel, HJ, Arai, H, Dawson, TM, Moore, DJ, and Emson, PC. "Localization of Parkinson's disease-associated LRRK2 in normal and pathological human brain." Brain Research 1155 (June 2007): 208-219. Full Text
  - West, AB, Moore, DJ, Choi, C, Andrabi, SA, Li, X, Dikeman, D, Biskup, S, Zhang, Z, Lim, K-L, Dawson, VL, and Dawson, TM. "Parkinson's disease-associated mutations in LRRK2 link enhanced GTP-binding and kinase activities to neuronal toxicity." Human Molecular Genetics 16, no. 2 (January 2, 2007): 223-232. Full Text
  - Biskup, S, Moore, DJ, Celsi, F, Higashi, S, West, AB, Andrabi, SA, Kurkinen, K, Yu, S-W, Savitt, JM, Waldvogel, HJ, Faull, RLM, Emson, PC, Torp, R, Ottersen, OP, Dawson, TM, and Dawson, VL. "Localization of LRRK2 to membranous and vesicular structures in mammalian brain." Annals of Neurology 60, no. 5 (November 2006): 557-569. Full Text
  - Smith, WW, Pei, Z, Jiang, H, Moore, DJ, Liang, Y, West, AB, Dawson, VL, Dawson, TM, and Ross, CA. "Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration." Proceedings of the National Academy of Sciences of the United States of America 102, no. 51 (December 13, 2005): 18676-18681. Full Text
  - West, AB, Moore, DJ, Biskup, S, Bugayenko, A, Smith, WW, Ross, CA, Dawson, VL, and Dawson, TM. "Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity." Proceedings of the National Academy of Sciences of the United States of America 102, no. 46 (November 3, 2005): 16842-16847. Full Text
  - West, AB, Dawson, VL, and Dawson, TM. "To die or grow: Parkinson's disease and cancer." Trends in Neurosciences 28, no. 7 (July 2005): 348-352. (Review) Full Text
  - West, AB, Kapatos, G, O'Farrell, C, Gonzalez-de-Chavez, F, Chiu, K, Farrer, MJ, and Maidment, NT. "N-myc regulates parkin expression." The Journal of Biological Chemistry 279, no. 28 (July 2004): 28896-28902. Full Text
  - West, AB, and Maidment, NT. "Genetics of parkin-linked disease." Human Genetics 114, no. 4 (March 2004): 327-336. (Review) Full Text
  - Lincoln, S, Wiley, J, Lynch, T, Langston, JW, Chen, R, Lang, A, Rogaeva, E, Sa, DS, Munhoz, RP, Harris, J, Marder, K, Klein, C, Bisceglio, G, Hussey, J, West, A, Hulihan, M, Hardy, J, and Farrer, M. "Parkin-proven disease: common founders but divergent phenotypes." Neurology 60, no. 10 (May 2003): 1605-1610. Full Text
  - West, AB, Gonzalez-de-Chavez, F, Wilkes, K, O'Farrell, C, and Farrer, MJ. "Parkin is not regulated by the unfolded protein response in human neuroblastoma cells." Neuroscience Letters 341, no. 2 (May 2003): 139-142. Full Text
  - West, AB, Lockhart, PJ, O'Farell, C, and Farrer, MJ. "Identification of a novel gene linked to parkin via a bi-directional promoter." Journal of Molecular Biology 326, no. 1 (February 2003): 11-19. Full Text
  - West, AB, Maraganore, D, Crook, J, Lesnick, T, Lockhart, PJ, Wilkes, KM, Kapatos, G, Hardy, JA, and Farrer, MJ. "Functional association of the parkin gene promoter with idiopathic Parkinson's disease." Human Molecular Genetics 11, no. 22 (October 2002): 2787-2792. Full Text
  - West, A, Periquet, M, Lincoln, S, Lücking, CB, Nicholl, D, Bonifati, V, Rawal, N, Gasser, T, Lohmann, E, Deleuze, J-F, Maraganore, D, Levey, A, Wood, N, Dürr, A, Hardy, J, Brice, A, Farrer, M, and French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility on Parkinson's Disease, . "Complex relationship between Parkin mutations and Parkinson disease." American Journal of Medical Genetics 114, no. 5 (July 2002): 584-591. Full Text
  - Wu, R-M, Shan, D-E, Sun, C-M, Liu, R-S, Hwu, W-L, Tai, C-H, Hussey, J, West, A, Gwinn-Hardy, K, Hardy, J, Chen, J, Farrer, M, and Lincoln, S. "Clinical, 18F-dopa PET, and genetic analysis of an ethnic Chinese kindred with early-onset parkinsonism and parkin gene mutations." Movement Disorders : Official Journal of the Movement Disorder Society 17, no. 4 (July 2002): 670-675. Full Text
  - West, A, Farrer, M, Petrucelli, L, Cookson, M, Lockhart, P, and Hardy, J. "Identification and characterization of the human parkin gene promoter." Journal of Neurochemistry 78, no. 5 (September 2001): 1146-1152. Full Text
  - West, AB, Zimprich, A, Lockhart, PJ, Farrer, M, Singleton, A, Holtom, B, Lincoln, S, Hofer, A, Hill, L, Müller-Myhsok, B, Wszolek, ZK, Hardy, J, and Gasser, T. "Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes." European Journal of Human Genetics : Ejhg 9, no. 9 (September 2001): 659-666. Full Text
  - Farrer, M, Maraganore, DM, Lockhart, P, Singleton, A, Lesnick, TG, de Andrade, M, West, A, de Silva, R, Hardy, J, and Hernandez, D. "alpha-Synuclein gene haplotypes are associated with Parkinson's disease." Human Molecular Genetics 10, no. 17 (August 2001): 1847-1851. Full Text
  - West, A, Periquet, M, Lincoln, S, Lucking, CB, Nicholl, D, Bonifati, V, Rawal, N, Gasser, T, Lohmann, E, Deuleuze, JF, Maraganore, D, Levey, A, Wood, N, Durr, A, Hardy, J, Brice, A, and Farrer, M. "Complex relationship between Parkin mutations and Parkinson disease (vol 114, pg 584, 2002)." American Journal of Medical Genetics 114, no. 8 (December 8, 2002): 992-992. Full Text Link to Item
  - West, A, Periquet, M, Lincoln, S, Lücking, CB, Nicholl, D, Bonifati, V, Rawal, N, Gasser, T, Lohmann, E, Deleuze, JF, Maraganore, D, Levey, A, Wood, N, Dürr, A, Hardy, J, Brice, A, and Farrer, M. "Erratum: Complex relationship between Parkin mutations and Parkinson disease (American Journal of Medical Genetics-Neuropsychocetric (2002) 114-(584-591))." American Journal of Medical Genetics Neuropsychiatric Genetics 114, no. 8 (December 8, 2002): 992-null. Full Text
- Book Sections
  - West, AB, Gray, M, and Standaert, DG. "Basal Ganglia Disorders." In Emery and Rimoin's Principles and Practice of Medical Genetics, 1-39. August 29, 2013. Full Text
- Conference Papers
  - Daher, JPL, West, A, and Hirst, W. "Pharmacological inhibition of LRRK2 blocks alpha-synuclein induced neurodegeneration in rats." 25th Biennial Meeting of the International-Society-for-Neurochemistry Jointly with the 13th Meeting of the Asian-Pacific-Society-for-Neurochemistry in Conjunction with the 35th Meeting of the Australasian-Neuroscience-Society. Cairns, AUSTRALIA. August 23, 2015 - August 27, 2015.: WILEY-BLACKWELL, August 1, 2015. Link to Item
  - Liu, Z, and Zou, M-H. "Macrophage Liver Kinase B-1 Interacts with IKK beta and Inhibits Inflammatory Signaling in Response to LPS." Experimental Biology Meeting. Boston, MA. March 28, 2015 - April 1, 2015.: FEDERATION AMER SOC EXP BIOL, April 1, 2015. Link to Item
  - Lockhart, PJ, West, AB, O'Farrell, CA, and Farrer, MJ. "Identification of a novel gene linked to Parkin via a bidirectional promoter." January 1, 2003.

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