Overview
Adjustment for misclassification
Missing data
Clinical trials
Analysis of cardiovascular and stroke data
Current Appointments & Affiliations
Professor of Biostatistics & Bioinformatics
·
2021 - Present
Biostatistics & Bioinformatics, Division of Biostatistics,
Biostatistics & Bioinformatics
Member in the Duke Clinical Research Institute
·
2003 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Early outcomes of off-label transcatheter tricuspid valve repair/replacement in the STS/ACC TVT registry.
Journal Article Am Heart J · May 2026 BACKGROUND: Transcatheter tricuspid valve interventions (TTVI) have expanded with the recent FDA approval of both replacement transcatheter tricuspid valve replacement (TTVR) and edge-to-edge repair (T-TEER) devices. However, the volume and outcomes of com ... Full text Link to item CiteImpact of Changes in Renal Function on Outcomes Following Mitral Transcatheter Edge-To-Edge Repair.
Journal Article Struct Heart · March 2026 BACKGROUND: Hemodynamic changes following mitral transcatheter edge-to-edge repair (mTEER) may impact estimated glomerular filtration rate (eGFR), but whether changes in eGFR following mTEER are associated with subsequent clinical outcomes is not known. Th ... Full text Link to item CiteHepatic Encephalopathy is the Key Driver of Symptom Burden in a Longitudinal Cohort of Patients With Advanced Chronic Liver Disease: PAL-LIVER Substudy.
Journal Article Am J Gastroenterol · February 13, 2026 INTRODUCTION: Cirrhosis is a chronic illness with high morbidity, marked by persistent physical and psychological symptoms that affect patients and their caregivers. Longitudinal data on symptom trajectories and their determinants, particularly hepatic enc ... Full text Link to item CiteRecent Grants
Effects of Blood and Blood-Derived Products on Meniscus Healing
ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2030In vivo ACL mechanics and risk factors for injury
ResearchCo Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2024 - 2029Biomarkers to Advance Clinical Phenotypes of Low Back Pain (BACk)
ResearchCo Investigator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2023 - 2028View All Grants
Education
University of Washington ·
1990
Ph.D.
University of Oxford (United Kingdom) ·
1984
M.S.