Overview
Dr. Andrew Nixon is Professor of Medicine in the Department of Medicine/Division of Medical Oncology at Duke University. He holds a BS in chemistry from Miami University, a PhD in biochemistry from Wake Forest University, and an MBA with a focus on healthcare management from Duke University/Fuqua School of Business. He is a nationally recognized expert in the development of cancer biomarkers and correlative science, with extensive experience leading large multi-center biomarker analyses. Dr. Nixon serves in various leadership roles within the National Cancer Institute (NCI), working with diverse multi-disciplinary teams focused on improving cancer patient outcomes through biomarker science. He serves as the national co-chair for the NCI Core Correlative Sciences Committee which adjudicates the use of biospecimens collected throughout the NCI National Clinical Trial Network (NCTN). Within the NCI-NCTN Alliance cooperative group, Dr. Nixon has multiple leadership positions including serving on the Alliance Board of Directors, co-chair of the Immuno-Oncology Committee, co-chair for Gastrointestinal Correlative Research, and has been an executive member of the Translational Research Program since its inception. Additionally, within the NCI-NCTN NRG cooperative group, he serves as a member of the Gynecologic Translational Science Committee and on the Gynecological Oncology Group - Partners Investigator Council Translational Research Subcommittee. Dr. Nixon is an American Society for Clinical Oncology (ASCO) Ambassador and has chaired various committees and led scientific and educational sessions at national conferences. Recently, Dr. Nixon has focused his research on cellular senescence and biomarkers of aging and early carcinogenesis. He serves as Principal Investigator for a large multi-center NIH grant to develop high-resolution tissue maps and biomarkers of cellular senescence as a part of the Senescence Network (SenNet) Consortium.
Current Appointments & Affiliations
Recent Publications
Abstract 7735: HER2 expression and tumor-infiltrating lymphocytes predict response to tucatinib plus trastuzumab in HER2 -positive metastatic colorectal cancer (MOUNTAINEER): Exploratory analysis of a multicenter, Phase II trial
Conference Cancer Research · April 3, 2026 AbstractIntroduction:The HER2-targeted doublet, tucatinib and trastuzumab, recently received FDA approval for previously treate ... Full text CiteAbstract 4802: Evaluation of the circulating angiome in cancer: Translational assessment of a 44-plex angiogenesis biomarker panel
Conference Cancer Research · April 3, 2026 AbstractAngiogenesis, the formation of new blood vessels from existing vasculature, is a hallmark of tumor progression, enabling malignant growth, invasion, and metastasis. Tumor-associated angiogenesis l ... Full text CiteAbstract 6750: Highly multiplexed immunoassays enable discovery of multimarker EV surface signatures as novel biomarkers
Conference Cancer Research · April 3, 2026 AbstractExtracellular vesicles (EVs) are lipid bilayer particles that mediate cell communication by carrying molecules that reflect their cell of origin. Their enrichment in disease states and accessibili ... Full text CiteRecent Grants
Targeting Hepatocyte Senescence to Improve NAFLD
ResearchAdvisor · Awarded by National Institute of Diabetes and Digestive and Kidney Diseases · 2024 - 2029Drug Development for Dystonia
ResearchCo Investigator · Awarded by Department of Defense · 2023 - 2027Duke ACS Institutional Research Grant
ResearchSignificant Contributor · Awarded by American Cancer Society, Inc. · 2024 - 2026View All Grants