Current Appointments & Affiliations
Associate Professor of Neurosurgery
·
2023 - Present
Neurosurgery,
Neurosurgery
Associate Professor in Pathology
·
2023 - Present
Pathology,
Clinical Science Departments
Associate Professor of Biomedical Engineering
·
2024 - Present
Biomedical Engineering,
Pratt School of Engineering
Member of the Duke Cancer Institute
·
2022 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
A surgical window of opportunity trial evaluating the effect of the PCSK9 inhibitor evolocumab on tumoral MHC-I expression and CD8+ infiltration in glioma.
Journal Article Sci Rep · October 23, 2025 Many cancers evade immunosurveillance by downregulating surface major histocompatibility class (MHC)-I. Proprotein convertase subtilisin/kexin type 9 (PCSK9) promotes MHC-I degradation and is elevated in glioma. Evolocumab is a clinically approved PCSK9 in ... Full text Link to item CiteIntraoperative brain tumor classification via laser-induced fluorescence spectroscopy and machine learning.
Journal Article J Neurosurg · August 1, 2025 OBJECTIVE: To optimize neurosurgical tumor resection, tissue types and borders must be appropriately identified. Authors of this study established the use of a nondestructive laser-based endogenous fluorescence spectroscopy device, "TumorID," to almost imm ... Full text Link to item CiteIndividualized dynamic risk assessment and treatment selection for multiple myeloma.
Journal Article Br J Cancer · June 2025 BACKGROUND: Individualized treatment decisions for multiple myeloma (MM) patients require accurate risk stratification that accounts for patient-specific consequences of cytogenetic abnormalities on disease progression. METHODS: Previously, SYstems Genetic ... Full text Link to item CiteRecent Grants
McCain/Bayh Glioblastoma Consortium
Clinical TrialCo Investigator · Awarded by Department of Defense · 2025 - 2029Integrating genome-wide association study data with single-cell `omics' to reveal the cellular effectors of glioblastoma predisposition
ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2029Integrative transcriptomic and epigenomic profiling of subependymal giant cell astrocytoma at single-cell resolution
ResearchCo Investigator · Awarded by Department of Defense · 2025 - 2027View All Grants
Education, Training & Certifications
Harvard Medical School ·
2009
M.D.