Research Interests
My research lab focuses on using single-cell sequencing techniques to study intratumoral heterogeneity in malignant brain tumors. Intratumoral heterogeneity is the idea that individual cancer cells within a patient’s tumor are different and can respond differently to treatments. I also have an active interest in developing patient-specific models of disease where we can learn how an individual patient's tumor might respond differently than another. My ultimate goal is to further advance precision medicine approaches for malignant brain tumors, and ensure that patients are getting the right treatments for their specific tumors.
Selected Grants
McCain/Bayh Glioblastoma Consortium
Clinical TrialCo Investigator · Awarded by Department of Defense · 2025 - 2029Integrating genome-wide association study data with single-cell `omics' to reveal the cellular effectors of glioblastoma predisposition
ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2029Integrative transcriptomic and epigenomic profiling of subependymal giant cell astrocytoma at single-cell resolution
ResearchCo Investigator · Awarded by Department of Defense · 2025 - 2027Pharmacologic Reversal of T cell Sequestration and Restoration of T cell Function to Enable Immunotherapeutic Success against Glioblastoma
FellowshipMentor · Awarded by Neurosurgery Research and Education Foundation · 2025 - 2027Deep interrogation and modeling of intratumoral heterogeneity, plasticity, and tumor evolution in glioblastoma
ResearchPrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2023 - 2026IL-1ss-mediated stimulation of the adrenergic systemic and immune polarization in a mouse model of stroke
FellowshipCo-Mentor · Awarded by Neurosurgery Research and Education Foundation · 2025 - 2026Licensing Immunotherapeutic Responses in GBM: Developing A Novel GPCR-Targeted Approach
ResearchSignificant Contributor · Awarded by Charlie Teo Foundation · 2024 - 2025Translating Single Cell Analysis into Actionable Therapeutic Strategies for Glioblastoma
ResearchPrincipal Investigator · Awarded by Kuni Foundation · 2023 - 2024External Relationships
- Servier Pharmaceuticals
- Sygnomics
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.