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Archan Chakraborty

Research Associate, Senior
Pharmacology & Cancer Biology

Overview


NHLBI K99 Fellow- 2025-2030
AHA Postdoctoral Fellow - 2023-2025

Research overview: Understanding the role of cardiomyocyte polyploidization using fly heart as a model system.

My research at Fox lab focuses on understanding the importance of cardiomyocyte polyploidization and finding regulators which can promote or inhibit cardiomyocyte regeneration using accessible Drosophila genetics.

Current Appointments & Affiliations


Recent Publications


Synaptic vesicle glycoprotein 2 enables viable aneuploidy following centrosome amplification.

Journal Article Genetics · October 8, 2025 Amplified centrosome number causes genomic instability, most severely through division into >2 aneuploid daughter cells (multipolar mitosis). Several mechanisms that suppress multipolar division have been uncovered, yet mechanisms that favor viable multipo ... Full text Link to item Cite

High-speed 4D fluorescence light field tomography of whole freely moving organisms.

Journal Article Optica · May 20, 2025 Volumetric fluorescence imaging techniques, such as confocal, multiphoton, light sheet, and light field microscopy, have become indispensable tools across a wide range of cellular, developmental, and neurobiological applications. However, it is difficult t ... Full text Link to item Cite
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Recent Grants


BII: Polyploidy: Integration Across Scales and Biological Systems

ResearchPost Doctoral Trainee · Awarded by University of Florida · 2024 - 2030

Leveraging Drosophila to identify novel and conserved regulators of cardiomyocyte polyploidy

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2025 - 2027

Polyploidy after tissue injury: a Drosophila model

ResearchPostdoctoral Associate · Awarded by National Institute of General Medical Sciences · 2016 - 2026

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