Overview
AHA Postdoctoral Fellow - 2023-2025
Research overview: Understanding the role of cardiomyocyte polyploidization using fly heart as a model system.
My research at Fox lab focuses on understanding the importance of cardiomyocyte polyploidization and finding regulators which can promote or inhibit cardiomyocyte regeneration using accessible Drosophila genetics.
Research overview: Understanding the role of cardiomyocyte polyploidization using fly heart as a model system.
My research at Fox lab focuses on understanding the importance of cardiomyocyte polyploidization and finding regulators which can promote or inhibit cardiomyocyte regeneration using accessible Drosophila genetics.
Current Appointments & Affiliations
Postdoctoral Associate
Pharmacology & Cancer Biology,
Basic Science Departments
Recent Publications
Conserved chamber-specific polyploidy maintains heart function in Drosophila.
Journal Article Development · August 15, 2023 Developmentally programmed polyploidy (whole-genome duplication) of cardiomyocytes is common across evolution. Functions of such polyploidy are essentially unknown. Here, in both Drosophila larvae and human organ donors, we reveal distinct polyploidy level ... Full text Link to item CiteDrosophila CTP synthase regulates collective cell migration by controlling the polarized endocytic cycle.
Journal Article Development (Cambridge, England) · August 2022 Phosphatidylinositol (PI) 4,5-bisphosphate (PIP2) is involved in many biological functions. However, the mechanisms of PIP2 in collective cell migration remain elusive. This study highlights the regulatory role of cytidine triphosphate synthase (CTPsyn) in ... Full text CiteSNAP29 mediates the assembly of histidine-induced CTP synthase filaments in proximity to the cytokeratin network.
Journal Article Journal of cell science · May 2020 Under metabolic stress, cellular components can assemble into distinct membraneless organelles for adaptation. One such example is cytidine 5'-triphosphate synthase (CTPS, for which there are CTPS1 and CTPS2 forms in mammals), which forms filamentous struc ... Full text CiteRecent Grants
Polyploidy after tissue injury: a Drosophila model
ResearchPostdoctoral Associate · Awarded by National Institute of General Medical Sciences · 2016 - 2025Developmental and Injury Regulation of Polyploidy in the Drosophila Heart
FellowshipPI-Fellow · Awarded by American Heart Association · 2023 - 2024View All Grants