Journal ArticleInterv Neuroradiol · March 26, 2025
ObjectiveIntra-arterial chemotherapy (IAC) is a well-established treatment for retinoblastoma (RB). However, there are no standardized recommendations regarding the choice of drugs. This study compares the outcomes of single- versus multi-drug therapy.Meth ...
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Journal ArticleAm J Ophthalmol Case Rep · December 2024
PURPOSE: Patients with conjunctival squamous cell carcinoma that present with persisting disease or recurrence following topical chemotherapy and/or surgery especially when invading the sclera are challenging to treat. Herein, we describe the use of high-d ...
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Journal ArticleOrbit · June 2024
Orbital tuberculosis is a manifestation of extra-pulmonary tuberculosis that is challenging to diagnose and treat. Here, we describe the pivotal role of serial imaging in the diagnosis and treatment of orbital tuberculosis. A 28-year-old male presented wit ...
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Journal ArticleClin Exp Ophthalmol · April 2024
In the current era of global health awareness for retinoblastoma (RB), the challenge that lies ahead of us is providing optimal care for children affected with RB in underdeveloped nations. The understanding of similarities and disparities between various ...
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Journal ArticleCase Rep Ophthalmol · 2024
INTRODUCTION: Conjunctival nevi are benign tumors that are commonly located at the nasal or temporal limbus and rarely in the fornix or tarsus. We report a case of a patient presenting with a solitary compound cystic nevus of the conjunctival fornix in the ...
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Journal ArticleSurv Ophthalmol · 2024
Chromosomal abnormalities that involve the MYCN gene are rare; however, it is one of the most commonly mutated genes in retinoblastoma (RB) after the RB1 gene. MYCN is amplified in approximately 1-9 % of all RB tumors. It plays a role in RB oncogenesis via ...
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Journal ArticleOphthalmic Plast Reconstr Surg · November 2023
PURPOSE: To determine treatment outcomes, recurrence rates, and predictors of recurrence, to inform future therapeutic approaches for spheno-orbital meningiomas (SOM). METHODS: A retrospective single-center study of SOM treated from 1990 to 2021 was conduc ...
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Journal ArticleOphthalmic Plast Reconstr Surg · January 2022
Neoadjuvant intra-arterial cytoreductive chemotherapy is used for the treatment of lacrimal gland adenoid cystic carcinomas (ACC) to improve outcomes in this condition with an otherwise dismal prognosis. We share our experience in the management of an adva ...
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Journal ArticleOcular Oncology and Pathology · December 1, 2021
We report delayed intravitreal pigment dispersion following Iodine-125 plaque brachytherapy, without evidence of tumor recurrence, in 4 patients treated for choroidal melanoma. These patients were treated with Iodine-125 plaque brachytherapy, with or witho ...
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Journal ArticleEur J Ophthalmol · July 2021
PURPOSE: To study the outcomes of cataract surgery in treated retinoblastoma (RB) eyes. METHODS: Retrospective study of 29 eyes of 27 patients. RESULTS: Based on International Classification of Intraocular Retinoblastoma, tumors belonged to group B (n = 3, ...
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Journal ArticleInt Ophthalmol · January 2021
PURPOSE: To describe anterior segment optical coherence tomography (AS-OCT) features of pseudoepitheliomatous hyperplasia (PEH) of the ocular surface. METHODS: This is a retrospective study of 9 lesions of 8 patients with histopathologically proven PEH RES ...
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Journal ArticleEye (Lond) · February 2020
PURPOSE: To describe the clinical features, histopathology and treatment of ocular surface squamous neoplasia (OSSN) with intraocular tumour extension. METHODS: Retrospective study of 23 patients. RESULTS: The mean age at presentation of OSSN with intraocu ...
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Journal ArticleInt Ophthalmol · January 2020
PURPOSE: To compare the clinical presentation and outcomes of retinoblastoma (RB) based on age at presentation. METHODS: Retrospective comparative study of 1940 eyes of 1450 children with RB. RESULTS: Presentation of RB with enlarged eyeball and eyelid swe ...
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Chapter · January 1, 2020
Retinal involvement in leukemia was first described by Liebreich in 1860. Since then, it has been shown that leukemia can involve nearly any eye structure. Since ocular symptoms can be the first manifestation of the disorder, it is imperative for ophthalmo ...
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Journal ArticleBMJ Case Rep · October 30, 2019
A 1-day-old child was brought to the clinic for evaluation of enlarged right eye (OD). On examination, OD showed buphthalmos with diffuse scleral melanocytosis, fleshy blackish-brown extrascleral mass with corneal extension, and secondary glaucoma. Anterio ...
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Journal ArticleAm J Ophthalmol · February 2019
PURPOSE: We studied the incidence, treatment, and outcome of ocular and periocular tumors in patients with xeroderma pigmentosum (XP). DESIGN: Retrospective case series. METHODS: This single-institution study included 120 patients with XP who underwent int ...
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