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Arthur Wakefield Baker

Associate Professor of Medicine
Medicine, Infectious Diseases

Selected Publications


A cluster of three extrapulmonary Mycobacterium abscessus infections linked to well-maintained water-based heater-cooler devices.

Journal Article Infect Control Hosp Epidemiol · May 2024 BACKGROUND: Various water-based heater-cooler devices (HCDs) have been implicated in nontuberculous mycobacteria outbreaks. Ongoing rigorous surveillance for healthcare-associated M. abscessus (HA-Mab) put in place following a prior institutional outbreak ... Full text Link to item Cite

Risk Factors for and Outcomes Following Early Acquisition of Mycobacterium abscessus Complex After Lung Transplantation.

Journal Article Open Forum Infect Dis · May 2024 BACKGROUND: Lung transplant recipients are at increased risk of Mycobacterium abscessus complex (MABC) acquisition and invasive infection. We analyzed risk factors and outcomes of early post-lung transplant MABC acquisition. METHODS: We conducted a retrosp ... Full text Link to item Cite

Mycobacterium immunogenum acquisition from hospital tap water: a genomic and epidemiologic analysis.

Journal Article J Clin Microbiol · May 1, 2024 We identified 23 cases of Mycobacterium immunogenum respiratory acquisition linked to a colonized plumbing system at a new hospital addition. We conducted a genomic and epidemiologic investigation to assess for clonal acquisition of M. immunogenum from hos ... Full text Link to item Cite

Risk factors, management, and clinical outcomes of invasive Mycoplasma and Ureaplasma infections after lung transplantation.

Journal Article Am J Transplant · April 2024 Mollicute infections, caused by Mycoplasma and Ureaplasma species, are serious complications after lung transplantation; however, understanding of the epidemiology and outcomes of these infections remains limited. We conducted a single-center retrospective ... Full text Open Access Link to item Cite

Gut microbiome correlates of recurrent urinary tract infection: a longitudinal, multi-center study

Journal Article eClinicalMedicine · January 1, 2024 Background: Urinary tract infections (UTI) affect approximately 250 million people annually worldwide. Patients often experience a cycle of antimicrobial treatment and recurrent UTI (rUTI) that is thought to be facilitated by a gut reservoir of uropathogen ... Full text Cite

Complete genome sequence of Mycobacterium immunogenum strain C14-1.MIM isolated from a hospitalized lung transplant recipient.

Journal Article Microbiol Resour Announc · December 14, 2023 Mycobacterium immunogenum is a rapidly growing nontuberculous mycobacteria species that can cause healthcare-associated infections. We report the complete genome of C14-1.MIM, isolated via culture of a respiratory specimen obtained from a hospitalized lung ... Full text Link to item Cite

Impact of measurement and feedback on chlorhexidine gluconate bathing among intensive care unit patients: A multicenter study.

Journal Article Infect Control Hosp Epidemiol · September 2023 OBJECTIVE: To assess whether measurement and feedback of chlorhexidine gluconate (CHG) skin concentrations can improve CHG bathing practice across multiple intensive care units (ICUs). DESIGN: A before-and-after quality improvement study measuring patient ... Full text Link to item Cite

Colon surgical-site infections and the impact of "present at the time of surgery (PATOS)" in a large network of community hospitals.

Journal Article Infect Control Hosp Epidemiol · August 2023 OBJECTIVES: To describe the epidemiology of complex colon surgical procedures (COLO), stratified by present at time of surgery (PATOS) surgical-site infections (SSIs) and non-PATOS SSIs and their impact on the epidemiology of colon-surgery SSIs. DESIGN: Re ... Full text Link to item Cite

Living kidney donors with HIV: experience and outcomes from a case series by the HOPE in Action Consortium.

Journal Article Lancet Reg Health Am · August 2023 BACKGROUND: Living kidney donation is possible for people living with HIV (PLWH) in the United States within research studies under the HIV Organ Policy Equity (HOPE) Act. There are concerns that donor nephrectomy may have an increased risk of end-stage re ... Full text Link to item Cite

Epidemiology, management, and clinical outcomes of extrapulmonary Mycobacterium abscessus complex infections in heart transplant and ventricular assist device recipients.

Journal Article Am J Transplant · July 2023 Nontuberculous mycobacteria are emerging pathogens, yet data on the epidemiology and management of extrapulmonary nontuberculous mycobacteria infections in orthotopic heart transplantation (OHT) and ventricular assist device (VAD) recipients are scarce. We ... Full text Link to item Cite

Use of Statistical Process Control Methods for Early Detection of Healthcare Facility-Associated Nontuberculous Mycobacteria Outbreaks: A Single-Center Pilot Study.

Journal Article Clin Infect Dis · April 17, 2023 BACKGROUND: Nontuberculous mycobacteria (NTM) are emerging pathogens increasingly implicated in healthcare facility-associated (HCFA) infections and outbreaks. We analyzed the performance of statistical process control (SPC) methods in detecting HCFA NTM o ... Full text Link to item Cite

Surgical site infection trends in community hospitals from 2013 to 2018.

Journal Article Infect Control Hosp Epidemiol · April 2023 OBJECTIVE: Sparse recent data are available on the epidemiology of surgical site infections (SSIs) in community hospitals. Our objective was to provide updated epidemiology data on complex SSIs in community hospitals and to characterize trends of SSI preva ... Full text Link to item Cite

Management of nontuberculous mycobacteria in lung transplant cases: an international Delphi study

Journal Article ERJ Open Research · March 1, 2023 Rationale Nontuberculous mycobacterial (NTM) diseases are difficult-to-treat infections, especially in lung transplant (LTx) candidates. Currently, there is a paucity of recommendations on the management of NTM infections in LTx, focusing on Mycobacterium ... Full text Cite

SEIR Model to address the impact of face masks amid COVID-19 pandemic.

Journal Article Risk Anal · January 2023 Early in the pandemic of coronavirus disease 2019 (COVID-19), face masks were used extensively by the general public in several Asian countries. The lower transmission rate of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Asian countr ... Full text Link to item Cite

Early recognition and response to increases in surgical site infections using optimised statistical process control charts-The early 2RIS trial: A multicentre stepped wedge cluster randomised controlled trial.

Journal Article EClinicalMedicine · December 2022 BACKGROUND: Traditional approaches for surgical site infection (SSI) surveillance have deficiencies that delay detection of SSI outbreaks and other clinically important increases in SSI rates. We investigated whether use of optimised statistical process co ... Full text Open Access Link to item Cite

Clinical Features and Treatment Outcomes of Pulmonary Mycobacterium avium-intracellulare Complex With and Without Coinfections.

Journal Article Open Forum Infect Dis · August 2022 Coinfections are more common in patients with cystic fibrosis and bronchiectasis. Infiltrates on imaging studies are seen more commonly in patients with coinfections, but coinfections did not affect treatment outcomes of pulmonary Mycobacterium avium compl ... Full text Open Access Link to item Cite

Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements.

Journal Article Cell Host Microbe · July 13, 2022 Large-scale genomic studies have identified within-host adaptation as a hallmark of bacterial infections. However, the impact of physiological, metabolic, and immunological differences between distinct niches on the pathoadaptation of opportunistic pathoge ... Full text Link to item Cite

Cytomegalovirus prevention in thoracic organ transplantation: A single-center evaluation of letermovir prophylaxis.

Journal Article J Heart Lung Transplant · April 2022 BACKGROUND: Cytomegalovirus (CMV) infection is common following thoracic organ transplantation and causes substantial morbidity and mortality. Letermovir is a novel antiviral agent used off-label in this population for CMV prevention. Our goal was to under ... Full text Link to item Cite

A cluster of three extrapulmonary Mycobacterium abscessus infections linked to well-maintained water-based heater-cooler devices.

Journal Article Infect Control Hosp Epidemiol · May 2024 BACKGROUND: Various water-based heater-cooler devices (HCDs) have been implicated in nontuberculous mycobacteria outbreaks. Ongoing rigorous surveillance for healthcare-associated M. abscessus (HA-Mab) put in place following a prior institutional outbreak ... Full text Link to item Cite

Risk Factors for and Outcomes Following Early Acquisition of Mycobacterium abscessus Complex After Lung Transplantation.

Journal Article Open Forum Infect Dis · May 2024 BACKGROUND: Lung transplant recipients are at increased risk of Mycobacterium abscessus complex (MABC) acquisition and invasive infection. We analyzed risk factors and outcomes of early post-lung transplant MABC acquisition. METHODS: We conducted a retrosp ... Full text Link to item Cite

Mycobacterium immunogenum acquisition from hospital tap water: a genomic and epidemiologic analysis.

Journal Article J Clin Microbiol · May 1, 2024 We identified 23 cases of Mycobacterium immunogenum respiratory acquisition linked to a colonized plumbing system at a new hospital addition. We conducted a genomic and epidemiologic investigation to assess for clonal acquisition of M. immunogenum from hos ... Full text Link to item Cite

Risk factors, management, and clinical outcomes of invasive Mycoplasma and Ureaplasma infections after lung transplantation.

Journal Article Am J Transplant · April 2024 Mollicute infections, caused by Mycoplasma and Ureaplasma species, are serious complications after lung transplantation; however, understanding of the epidemiology and outcomes of these infections remains limited. We conducted a single-center retrospective ... Full text Open Access Link to item Cite

Gut microbiome correlates of recurrent urinary tract infection: a longitudinal, multi-center study

Journal Article eClinicalMedicine · January 1, 2024 Background: Urinary tract infections (UTI) affect approximately 250 million people annually worldwide. Patients often experience a cycle of antimicrobial treatment and recurrent UTI (rUTI) that is thought to be facilitated by a gut reservoir of uropathogen ... Full text Cite

Complete genome sequence of Mycobacterium immunogenum strain C14-1.MIM isolated from a hospitalized lung transplant recipient.

Journal Article Microbiol Resour Announc · December 14, 2023 Mycobacterium immunogenum is a rapidly growing nontuberculous mycobacteria species that can cause healthcare-associated infections. We report the complete genome of C14-1.MIM, isolated via culture of a respiratory specimen obtained from a hospitalized lung ... Full text Link to item Cite

Impact of measurement and feedback on chlorhexidine gluconate bathing among intensive care unit patients: A multicenter study.

Journal Article Infect Control Hosp Epidemiol · September 2023 OBJECTIVE: To assess whether measurement and feedback of chlorhexidine gluconate (CHG) skin concentrations can improve CHG bathing practice across multiple intensive care units (ICUs). DESIGN: A before-and-after quality improvement study measuring patient ... Full text Link to item Cite

Colon surgical-site infections and the impact of "present at the time of surgery (PATOS)" in a large network of community hospitals.

Journal Article Infect Control Hosp Epidemiol · August 2023 OBJECTIVES: To describe the epidemiology of complex colon surgical procedures (COLO), stratified by present at time of surgery (PATOS) surgical-site infections (SSIs) and non-PATOS SSIs and their impact on the epidemiology of colon-surgery SSIs. DESIGN: Re ... Full text Link to item Cite

Living kidney donors with HIV: experience and outcomes from a case series by the HOPE in Action Consortium.

Journal Article Lancet Reg Health Am · August 2023 BACKGROUND: Living kidney donation is possible for people living with HIV (PLWH) in the United States within research studies under the HIV Organ Policy Equity (HOPE) Act. There are concerns that donor nephrectomy may have an increased risk of end-stage re ... Full text Link to item Cite

Epidemiology, management, and clinical outcomes of extrapulmonary Mycobacterium abscessus complex infections in heart transplant and ventricular assist device recipients.

Journal Article Am J Transplant · July 2023 Nontuberculous mycobacteria are emerging pathogens, yet data on the epidemiology and management of extrapulmonary nontuberculous mycobacteria infections in orthotopic heart transplantation (OHT) and ventricular assist device (VAD) recipients are scarce. We ... Full text Link to item Cite

Use of Statistical Process Control Methods for Early Detection of Healthcare Facility-Associated Nontuberculous Mycobacteria Outbreaks: A Single-Center Pilot Study.

Journal Article Clin Infect Dis · April 17, 2023 BACKGROUND: Nontuberculous mycobacteria (NTM) are emerging pathogens increasingly implicated in healthcare facility-associated (HCFA) infections and outbreaks. We analyzed the performance of statistical process control (SPC) methods in detecting HCFA NTM o ... Full text Link to item Cite

Surgical site infection trends in community hospitals from 2013 to 2018.

Journal Article Infect Control Hosp Epidemiol · April 2023 OBJECTIVE: Sparse recent data are available on the epidemiology of surgical site infections (SSIs) in community hospitals. Our objective was to provide updated epidemiology data on complex SSIs in community hospitals and to characterize trends of SSI preva ... Full text Link to item Cite

Management of nontuberculous mycobacteria in lung transplant cases: an international Delphi study

Journal Article ERJ Open Research · March 1, 2023 Rationale Nontuberculous mycobacterial (NTM) diseases are difficult-to-treat infections, especially in lung transplant (LTx) candidates. Currently, there is a paucity of recommendations on the management of NTM infections in LTx, focusing on Mycobacterium ... Full text Cite

SEIR Model to address the impact of face masks amid COVID-19 pandemic.

Journal Article Risk Anal · January 2023 Early in the pandemic of coronavirus disease 2019 (COVID-19), face masks were used extensively by the general public in several Asian countries. The lower transmission rate of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Asian countr ... Full text Link to item Cite

Early recognition and response to increases in surgical site infections using optimised statistical process control charts-The early 2RIS trial: A multicentre stepped wedge cluster randomised controlled trial.

Journal Article EClinicalMedicine · December 2022 BACKGROUND: Traditional approaches for surgical site infection (SSI) surveillance have deficiencies that delay detection of SSI outbreaks and other clinically important increases in SSI rates. We investigated whether use of optimised statistical process co ... Full text Open Access Link to item Cite

Clinical Features and Treatment Outcomes of Pulmonary Mycobacterium avium-intracellulare Complex With and Without Coinfections.

Journal Article Open Forum Infect Dis · August 2022 Coinfections are more common in patients with cystic fibrosis and bronchiectasis. Infiltrates on imaging studies are seen more commonly in patients with coinfections, but coinfections did not affect treatment outcomes of pulmonary Mycobacterium avium compl ... Full text Open Access Link to item Cite

Persisting uropathogenic Escherichia coli lineages show signatures of niche-specific within-host adaptation mediated by mobile genetic elements.

Journal Article Cell Host Microbe · July 13, 2022 Large-scale genomic studies have identified within-host adaptation as a hallmark of bacterial infections. However, the impact of physiological, metabolic, and immunological differences between distinct niches on the pathoadaptation of opportunistic pathoge ... Full text Link to item Cite

Cytomegalovirus prevention in thoracic organ transplantation: A single-center evaluation of letermovir prophylaxis.

Journal Article J Heart Lung Transplant · April 2022 BACKGROUND: Cytomegalovirus (CMV) infection is common following thoracic organ transplantation and causes substantial morbidity and mortality. Letermovir is a novel antiviral agent used off-label in this population for CMV prevention. Our goal was to under ... Full text Link to item Cite

COVID-19 Trials: Who Participates and Who Benefits?

Journal Article South Med J · April 2022 OBJECTIVES: The coronavirus disease 2019 (COVID-19) pandemic has disproportionately afflicted vulnerable populations. Older adults, particularly residents of nursing facilities, represent a small percentage of the population but account for 40% of mortalit ... Full text Open Access Link to item Cite

Genomic Analysis of a Hospital-Associated Outbreak of Mycobacterium abscessus: Implications on Transmission.

Journal Article Journal of clinical microbiology · January 2022 Whole-genome sequencing (WGS) has recently been used to investigate acquisition of Mycobacterium abscessus. Investigators have reached conflicting conclusions about the meaning of genetic distances for interpretation of person-to-person transmission. Exist ... Full text Cite

93. Early Recognition and Response to Increases in Surgical Site Infections (SSI) using Optimized Statistical Process Control (SPC) Charts – the Early 2RIS Trial: A Multicenter Stepped Wedge Cluster Randomized Controlled Trial (RCT)

Conference Open Forum Infectious Diseases · December 4, 2021 AbstractBackgroundTraditional approaches for SSI surveillance have deficiencies that can delay detection of SSI outbreaks and other cl ... Full text Cite

Tap Water Avoidance Decreases Rates of Hospital-onset Pulmonary Nontuberculous Mycobacteria.

Journal Article Clin Infect Dis · August 2, 2021 We analyzed the impact of a hospital tap water avoidance protocol on respiratory isolation of nontuberculous mycobacteria (NTM). After protocol implementation, hospital-onset episodes of respiratory NTM isolation on high-risk units decreased from 41.0 to 9 ... Full text Link to item Cite

Monitoring scheme for early detection of coronavirus and other respiratory virus outbreaks

Journal Article Computers and Industrial Engineering · June 1, 2021 In December 2019, an outbreak of pneumonia caused by a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) began in Wuhan, China. SARS-CoV-2 exhibited efficient person-to-person transmission of what became labeled as COVID-19. ... Full text Cite

Reduction in Expected Survival Associated With Nontuberculous Mycobacterial Pulmonary Disease.

Journal Article Clin Infect Dis · May 18, 2021 BACKGROUND: Nontuberculous mycobacteria (NTM) are opportunistically pathogenic bacteria that are found abundantly in the soil and water. Susceptible individuals exposed to NTM-containing aerosols from environmental sources may develop NTM pulmonary disease ... Full text Link to item Cite

Social Disadvantage, Politics, and Severe Acute Respiratory Syndrome Coronavirus 2 Trends: A County-level Analysis of United States Data.

Journal Article Clin Infect Dis · May 18, 2021 BACKGROUND: Understanding the epidemiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is essential for public health control efforts. Social, demographic, and political characteristics at the United States (US) county level might be as ... Full text Open Access Link to item Cite

Mortality outcomes with hydroxychloroquine and chloroquine in COVID-19 from an international collaborative meta-analysis of randomized trials.

Journal Article Nat Commun · April 15, 2021 Substantial COVID-19 research investment has been allocated to randomized clinical trials (RCTs) on hydroxychloroquine/chloroquine, which currently face recruitment challenges or early discontinuation. We aim to estimate the effects of hydroxychloroquine a ... Full text Open Access Link to item Cite

Invasive Mycobacterium abscessus Complex Infection After Cardiac Surgery: Epidemiology, Management, and Clinical Outcomes.

Journal Article Clin Infect Dis · April 8, 2021 BACKGROUND: We recently mitigated a clonal outbreak of hospital-acquired Mycobacterium abscessus complex (MABC), which included a large cluster of adult patients who developed invasive infection after exposure to heater-cooler units during cardiac surgery. ... Full text Link to item Cite

Variability in the Management of Adults With Pulmonary Nontuberculous Mycobacterial Disease.

Journal Article Clin Infect Dis · April 8, 2021 BACKGROUND: The increasing global prevalence of pulmonary nontuberculous mycobacteria (NTM) disease has called attention to challenges in NTM diagnosis and management. This study was conducted to understand management and outcomes of patients with pulmonar ... Full text Link to item Cite

Reply to Marinelli and Rotstein.

Journal Article Clin Infect Dis · January 27, 2021 Full text Link to item Cite

Rapidly Growing Mycobacterial Infections in Transplant: Evolving Epidemiology and Treatment Options

Chapter · January 1, 2021 Rapidly growing mycobacteria (RGM) are environmental microorganisms that thrive in water-associated biofilms and grow more quickly in the laboratory than slow-growing nontuberculous mycobacteria. Prevalence of RGM infection appears to be increasing, and pa ... Full text Cite

877. Use of Statistical Process Control Charts for Early Detection of Healthcare Facility-Associated Nontuberculous Mycobacterial Outbreaks

Conference Open Forum Infectious Diseases · December 31, 2020 AbstractBackgroundNontuberculous mycobacteria (NTM) are increasingly implicated in healthcare facility-associated (HCFA) outbreaks. Ho ... Full text Cite

Early recognition and response to increases in surgical site infections using optimized statistical process control charts-the Early 2RIS Trial: a multicenter cluster randomized controlled trial with stepped wedge design.

Journal Article Trials · October 28, 2020 BACKGROUND: Surgical site infections (SSIs) cause significant patient suffering. Surveillance and feedback of SSI rates is an evidence-based strategy to reduce SSIs, but traditional surveillance methods are slow and prone to bias. The objective of this clu ... Full text Link to item Cite

Large-scale empirical optimisation of statistical control charts to detect clinically relevant increases in surgical site infection rates.

Journal Article BMJ Qual Saf · June 2020 OBJECTIVE: Surgical site infections (SSIs) are common costly hospital-acquired conditions. While statistical process control (SPC) use in healthcare has increased, limited rigorous empirical research compares and optimises these methods for SSI surveillanc ... Full text Link to item Cite

Reply to Authors (Drs. Marinelli and Rotstein).

Journal Article Clin Infect Dis · May 23, 2020 Full text Link to item Cite

Impact of molecular testing on reported Clostridoides difficile infection rates.

Journal Article Infect Control Hosp Epidemiol · March 2020 BACKGROUND: The reported incidence of Clostridoides difficile infection (CDI) has increased in recent years, partly due to broadening adoption of nucleic acid amplification tests (NAATs) replacing enzyme immunoassay (EIA) methods. Our aim was to quantify t ... Full text Link to item Cite

Invasive Fungal Infection After Lung Transplantation: Epidemiology in the Setting of Antifungal Prophylaxis.

Journal Article Clin Infect Dis · January 1, 2020 BACKGROUND: Lung transplant recipients commonly develop invasive fungal infections (IFIs), but the most effective strategies to prevent IFIs following lung transplantation are not known. METHODS: We prospectively collected clinical data on all patients who ... Full text Link to item Cite

1386. Reduction in Expected Survival Associated with Nontuberculous Mycobacterial Pulmonary Infection

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundNontuberculous mycobacteria (NTM) are emerging agents of pulmonary disease, estimated to affect >80,000 people in ... Full text Cite

1232. Potential Health and Cost Outcomes of Optimized Statistical Process Control Use for Surgical Site Infection Surveillance

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundSurgical site infections (SSIs) are common (160,000–300,000 per year in the United States) and costly ($6,000–$25,50 ... Full text Cite

2426. Performance of Statistical Process Control Charts for Detecting Clinically-Significant Increases in Clostridium difficile Infection Rates

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundClostridium difficile infections (CDIs) are the most common type of healthcare-associated infection in the United St ... Full text Cite

572. Relationship Between Chlorhexidine Gluconate (CHG) Skin Concentrations and Microbial Skin Colonization among Medical Intensive Care Unit (MICU) Patients

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundCHG bathing is used to suppress patients’ microbial skin colonization, in order to prevent infections and transmissi ... Full text Cite

1758. Epidemiology of Invasive Mycoplasma and Ureaplasma Infections Early after Lung Transplantation

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundMycoplasma and Ureaplasma species can cause invasive infections early after lung transplant that are difficult to di ... Full text Cite

895. Impact of Measurement and Results Feedback of Chlorhexidine Gluconate (CHG) Skin Concentrations in Medical Intensive Care Unit (MICU) Patients Receiving CHG Bathing

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundHigher CHG skin levels may be needed to adequately control infection and transmission of pathogens in the ICU. We as ... Full text Cite

85. Use of Dual Statistical Process Control Charts for Early Detection of Surgical Site Infection Outbreaks at a Community Hospital Network

Conference Open Forum Infectious Diseases · October 23, 2019 AbstractBackgroundWe recently showed that the empirical use of a combination of 2 moving average (MA) statistical process control (SPC ... Full text Cite

Use of Letermovir as Salvage Therapy for Drug-Resistant Cytomegalovirus Retinitis.

Journal Article Antimicrob Agents Chemother · March 2019 Treatment options for drug-resistant cytomegalovirus (CMV) are limited. Letermovir is a novel antiviral recently approved for CMV prophylaxis following hematopoietic cell transplantation, but its efficacy in other settings is unknown. We recently used lete ... Full text Open Access Link to item Cite

1897. Letermovir Salvage for Complicated Cases of Resistant CMV

Conference Open Forum Infectious Diseases · November 26, 2018 Full text Cite

2121. Shifting Surgical Site Infection Denominators and Implication on NHSN Reporting

Conference Open Forum Infectious Diseases · November 26, 2018 Full text Cite

1251. Contaminated Sinks May be an Environmental Source for Serial Transmission of Carbapenem-Resistant Enterobacteriaceae (CRE) to ICU Patients

Conference Open Forum Infectious Diseases · November 26, 2018 AbstractBackgroundWe performed an investigation after noting an increase in hospital-onset (HO) KPC-producing Enterobacteriaceae (KPC- ... Full text Cite

927. Tap Water Avoidance Decreases Rates of Nontuberculous Mycobacteria in Intensive Care Units

Conference Open Forum Infectious Diseases · November 26, 2018 AbstractBackgroundWe recently investigated a clonal outbreak of Mycobacterium abscessus molecularly linked to a colonized water supply ... Full text Cite

Performance of statistical process control methods for regional surgical site infection surveillance: a 10-year multicentre pilot study.

Journal Article BMJ Qual Saf · August 2018 BACKGROUND: Traditional strategies for surveillance of surgical site infections (SSI) have multiple limitations, including delayed and incomplete outbreak detection. Statistical process control (SPC) methods address these deficiencies by combining longitud ... Full text Link to item Cite

Denominator Matters in Estimating Antimicrobial Use: A Comparison of Days Present and Patient Days.

Journal Article Infect Control Hosp Epidemiol · May 2018 Patient days and days present were compared to directly measured person time to quantify how choice of different denominator metrics may affect antimicrobial use rates. Overall, days present were approximately one-third higher than patient days. This diffe ... Full text Link to item Cite

Real-Time Surveillance of Influenza Morbidity: Tracking Intensive Care Unit Resource Utilization.

Journal Article Ann Am Thorac Soc · December 2017 RATIONALE: Existing real-time surveillance of influenza morbidity, based primarily on time-trended U.S. hospitalization and death data, is inadequate. These surveillance methods do not accurately predict hospital resource requirements or sufficiently captu ... Full text Link to item Cite

Invasive Mycobacterium abscessus Infection after Cardiac Surgery: Epidemiology and Clinical Outcomes

Conference Open Forum Infectious Diseases · October 1, 2017 AbstractBackgroundWe recently mitigated a clonal outbreak of Mycobacterium abscessus, including a large cluster of patients who develo ... Full text Cite

The Effect of National Healthcare Safety Network (NHSN) Rebaselining on Community Hospital SIRs

Conference Open Forum Infectious Diseases · October 1, 2017 AbstractBackgroundThe NHSN recently updated risk adjustment models and “rebaselined” Standardized Infection Ratios (SIRs) for healthca ... Full text Cite

Two-Phase Hospital-Associated Outbreak of Mycobacterium abscessus: Investigation and Mitigation.

Journal Article Clin Infect Dis · April 1, 2017 BACKGROUND: Nontuberculous mycobacteria (NTM) commonly colonize municipal water supplies and cause healthcare-associated outbreaks. We investigated a biphasic outbreak of Mycobacterium abscessus at a tertiary care hospital. METHODS: Case patients had recen ... Full text Link to item Cite

Mycobacterium Abscessus Infection in Patients with Ventricular Assist Devices

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 1, 2017 Link to item Cite

Invasive Mycobacterium abscessus Infection in Heart Transplant Recipients

Conference JOURNAL OF HEART AND LUNG TRANSPLANTATION · April 1, 2017 Link to item Cite

Clinical Outcomes and Healthcare Utilization Related to Multidrug-Resistant Gram-Negative Infections in Community Hospitals.

Journal Article Infect Control Hosp Epidemiol · January 2017 OBJECTIVE To evaluate the impact of multidrug-resistant gram-negative rod (MDR-GNR) infections on mortality and healthcare resource utilization in community hospitals. DESIGN Two matched case-control analyses. SETTING Six community hospitals participating ... Full text Link to item Cite

Mycobacterium abscessus Infection in Solid Organ Transplant Recipients

Conference Open Forum Infectious Diseases · December 1, 2016 Full text Cite

Epidemiology of Surgical Site Infection in a Community Hospital Network.

Journal Article Infect Control Hosp Epidemiol · May 2016 OBJECTIVE: To describe the epidemiology of complex surgical site infection (SSI) following commonly performed surgical procedures in community hospitals and to characterize trends of SSI prevalence rates over time for MRSA and other common pathogens METHOD ... Full text Link to item Cite

An Automated Surveillance Strategy to Identify Infectious Complications After Cardiac Implantable Electronic Device Procedures.

Journal Article Open Forum Infect Dis · December 2015 Background.  The optimum approach for infectious complication surveillance for cardiac implantable electronic device (CIED) procedures is unclear. We created an automated surveillance tool for infectious complications after CIED procedures. Methods.  Adult ... Full text Open Access Link to item Cite

Short Operative Duration and Surgical Site Infection Risk in Hip and Knee Arthroplasty Procedures.

Journal Article Infect Control Hosp Epidemiol · December 2015 OBJECTIVE: To determine the association (1) between shorter operative duration and surgical site infection (SSI) and (2) between surgeon median operative duration and SSI risk among first-time hip and knee arthroplasties. DESIGN: Retrospective cohort study ... Full text Link to item Cite

Seasonal Variation of Common Surgical Site Infections: Does Season Matter?

Journal Article Infect Control Hosp Epidemiol · September 2015 OBJECTIVE: To evaluate seasonal variation in the rate of surgical site infections (SSI) following commonly performed surgical procedures. DESIGN: Retrospective cohort study. METHODS: We analyzed 6 years (January 1, 2007, through December 31, 2012) of data ... Full text Link to item Cite

Postoperative infection in spine surgery: does the month matter?

Journal Article J Neurosurg Spine · July 2015 OBJECT: The relationship between time of year and surgical site infection (SSI) following neurosurgical procedures is poorly understood. Authors of previous reports have demonstrated that rates of SSI following neurosurgical procedures performed during the ... Full text Link to item Cite

The potential impact of excluding funguria from the surveillance definition of catheter-associated urinary tract infection.

Journal Article Infect Control Hosp Epidemiol · April 2015 Funguria rarely represents true infection in the urinary tract. Excluding yeast from the catheter-associated urinary tract infection (CAUTI) surveillance definition reduced CAUTI rates by nearly 25% in community hospitals and at an academic, tertiary-care ... Full text Link to item Cite

A comparison between National Healthcare Safety Network laboratory-identified event reporting versus traditional surveillance for Clostridium difficile infection.

Journal Article Infect Control Hosp Epidemiol · February 2015 OBJECTIVE Hospitals in the National Healthcare Safety Network began reporting laboratory-identified (LabID) Clostridium difficile infection (CDI) events in January 2013. Our study quantified the differences between the LabID and traditional surveillance me ... Full text Link to item Cite

910Seasonal Variation of Surgical Site Infections Following Common Procedures

Conference Open Forum Infectious Diseases · December 1, 2014 Full text Cite

Methicillin-resistant Staphylococcus aureus bloodstream infection surveillance: National Healthcare Safety Network's laboratory-identified event reporting versus traditional laboratory-confirmed bloodstream infection surveillance.

Journal Article Infect Control Hosp Epidemiol · October 2014 Hospitals must report cases of methicillin-resistant Staphylococcus aureus bloodstream infection (BSI) using a new laboratory-identified (LabID) event reporting module. BSI rates obtained using LabID differ from rates of BSI obtained from traditional surve ... Full text Link to item Cite

Surveying the surveillance: surgical site infections excluded by the January 2013 updated surveillance definitions.

Journal Article Infect Control Hosp Epidemiol · May 2014 The updated 2013 Centers for Disease Control and Prevention/National Healthcare Safety Network definitions for surgical site infections (SSIs) reduced the duration of prolonged surveillance from 1 year to 90 days and defined which procedure types require p ... Full text Link to item Cite

Local influenza-like illness surveillance at a university health system during the 2009 H1N1 influenza pandemic.

Journal Article Am J Infect Control · September 2012 BACKGROUND: The 2009 novel H1N1 influenza epidemic generated interest in regional and national influenza surveillance methods. Some systems revamped traditional syndromic and laboratory surveillance techniques, whereas others tracked influenza by Internet- ... Full text Link to item Cite