Overview
My research interest is clinical nephrology. Study types include retrospective reviews of patients with various clinical disorders as well as interventional trials.
I was the Principal Investigator at Duke for the Dialysis Access Consortium trials that attempted to identify pharmacologic interventions which could improve hemodialysis access outcomes.
Other interests include management of clinical renal disorders, treatment of hyponatremia and other electrolyte disorders, and use of vasopressin receptor antagonists. I serve as Editor of the National Kidney Foundation Primer on Kidney Diseases.
I was the Principal Investigator at Duke for the Dialysis Access Consortium trials that attempted to identify pharmacologic interventions which could improve hemodialysis access outcomes.
Other interests include management of clinical renal disorders, treatment of hyponatremia and other electrolyte disorders, and use of vasopressin receptor antagonists. I serve as Editor of the National Kidney Foundation Primer on Kidney Diseases.
Current Appointments & Affiliations
Professor Emeritus of Medicine
·
2014 - Present
Medicine, Nephrology,
Medicine
Recent Publications
Diagnosis and Management of Disorders of Body Tonicity-Hyponatremia and Hypernatremia: Core Curriculum 2020.
Journal Article Am J Kidney Dis · February 2020 Overall body fluid concentration is regulated within a narrow range by the concerted action of the hypothalamic-pituitary axis to influence water intake through thirst and water excretion via the effect of vasopressin, or antidiuretic hormone, on renal col ... Full text Link to item CiteDysnatremias
Chapter · January 1, 2019 Full text CiteHypovolemic Hyponatremia.
Journal Article Front Horm Res · 2019 The etiology of hyponatremia is often multifactorial. The most common causes include hypovolemia from gastrointestinal (GI) or other fluid losses, thiazide diuretics, and SIAD [1]. In this chapter, we will discuss hypovolemic ... Full text Link to item CiteRecent Grants
Nocturnal Deterusor Overactivity In Overactive Bladder Syndrome
ResearchCo Investigator · Awarded by National Institutes of Health · 2010 - 2014Pharmacologic Prevention of Arteriovenous Graft Thrombosis
ResearchMentor · Awarded by National Institutes of Health · 2007 - 2009Hemodialysis Vascular Access Clinical Trials Consortium
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2009View All Grants
Education, Training & Certifications
Washington University in St. Louis ·
1975
M.D.