Scholars@Duke
Arthur Greenberg

Arthur Greenberg

Professor Emeritus of Medicine
Medicine, Nephrology
Duke Box 2747, Durham, NC 27710
2424 Erwin Road, Suite 605, Durham, NC 27705

Selected Publications

Diagnosis and Management of Disorders of Body Tonicity-Hyponatremia and Hypernatremia: Core Curriculum 2020.

Journal Article Am J Kidney Dis · February 2020 Overall body fluid concentration is regulated within a narrow range by the concerted action of the hypothalamic-pituitary axis to influence water intake through thirst and water excretion via the effect of vasopressin, or antidiuretic hormone, on renal col ... Full text Link to item Cite

Dysnatremias

Chapter · January 1, 2019 Full text Cite

Hypovolemic Hyponatremia.

Journal Article Front Horm Res · 2019 The etiology of hyponatremia is often multifactorial. The most common causes include hypovolemia from gastrointestinal (GI) or other fluid losses, thiazide diuretics, and SIAD [1]. In this chapter, we will discuss hypovolemic ... Full text Link to item Cite

Use of Diuretics in Chronic Kidney Disease Patients

Chapter · January 1, 2019 Diuretics are commonly prescribed to treat the sodium retention, volume expansion, and hypertension characteristic of chronic kidney disease (CKD). With reduced renal function, delivery of the drugs to their renal tubular sites of action is impaired, poten ... Full text Cite

Euvolemic hyponatremia in cancer patients. Report of the Hyponatremia Registry: an observational multicenter international study.

Journal Article Support Care Cancer · July 2017 PURPOSE: Hyponatremia secondary to SIADH is frequent in cancer patients and potentially deleterious. The aim of this sub-analysis of the Hyponatremia Registry database is to analyze current diagnostic and therapeutic management practices in cancer patients ... Full text Link to item Cite

Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study.

Journal Article Am J Nephrol · 2017 BACKGROUND: Hyponatremia is a frequent and potentially life-threatening adverse side effect of thiazide diuretics. This sub-analysis of the Hyponatremia Registry database focuses on current management practices of thiazide-associated hyponatremia (TAH) and ... Full text Link to item Cite

Urinalysis and Urine Microscopy

Chapter · January 1, 2017 The urinalysis is an essential component of the evaluation of patients with suspected parenchymal kidney disease and helps distinguish among the various causes of glomerular disease and acute or chronic kidney injury. It can be performed rapidly and at lit ... Full text Cite

Diagnosing and Treating the Syndrome of Inappropriate Antidiuretic Hormone Secretion.

Journal Article Am J Med · May 2016 BACKGROUND: The syndrome of inappropriate antidiuretic hormone secretion is the most common cause of hyponatremia in clinical practice, but current management of hyponatremia and outcomes in patients with syndrome of inappropriate antidiuretic hormone secr ... Full text Link to item Cite

The effect of location and configuration on forearm and upper arm hemodialysis arteriovenous grafts.

Conference J Vasc Surg · November 2015 OBJECTIVE: The arteriovenous graft (AVG) is most often used in hemodialysis patients when an autogenous fistula is not feasible. The optimal location (forearm or upper arm) and configuration (loop or straight) of AVGs are not known. To evaluate relationshi ... Full text Link to item Cite

Current treatment practice and outcomes. Report of the hyponatremia registry.

Journal Article Kidney Int · July 2015 Current management practices for hyponatremia (HN) are incompletely understood. The HN Registry has recorded diagnostic measures, utilization, efficacy, and outcomes of therapy for eu- or hypervolemic HN. To better understand current practices, we analyzed ... Full text Link to item Cite

Use of Diuretics in Chronic Kidney Disease Patients

Chapter · January 1, 2015 Diuretics are commonly prescribed to treat the sodium retention, volume expansion, and hypertension characteristic of CKD. With reduced renal function, delivery of the drugs to their renal tubular sites of action is impaired, potentially leading to diminis ... Full text Cite

The reply.

Journal Article Am J Med · July 2014 Full text Link to item Cite

Diagnosis, evaluation, and treatment of hyponatremia: expert panel recommendations.

Journal Article Am J Med · October 2013 Hyponatremia is a serious, but often overlooked, electrolyte imbalance that has been independently associated with a wide range of deleterious changes involving many different body systems. Untreated acute hyponatremia can cause substantial morbidity and m ... Full text Link to item Cite

Role of vaptans in the management of hyponatremia.

Journal Article Am J Kidney Dis · August 2013 Hyponatremia, the most commonly encountered electrolyte abnormality, affects as many as 30% of hospitalized patients. It is a powerful predictor of poor outcomes, especially in patients with congestive heart failure or cirrhosis. The failure to excrete ele ... Full text Link to item Cite

Vasopressin receptor antagonists

Chapter · January 1, 2013 Arginine vasopressin is the hormone principally responsible for the genesis of most hyponatremic disorders. The persistent inappropriate or maladaptive secretion of this hormone, also known as antidiuretic hormone, prevents excretion of electrolyte-free wa ... Full text Cite

Urinalysis and urine microscopy

Chapter · January 1, 2013 Full text Cite

Design of a prospective, multinational registry to evaluate patients hospitalized with hyponatremia: The HN Registry

Journal Article Open Access Journal of Clinical Trials · January 1, 2012 Background: Hyponatremia is a prevalent condition in patients hospitalized across a broad range of conditions, including heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone (SIADH) secretion. Whether present on admission or dev ... Full text Cite

Hyponatremia and the use of vasopressin receptor antagonists in critically ill patients.

Journal Article J Intensive Care Med · 2012 Hyponatremia in critically ill patients is a common and challenging problem. Increased levels of arginine vasopressin almost always contribute to the etiology. Inhibition of the vasopressin receptor with a vasopressin receptor antagonist (vaptan) is a nove ... Full text Link to item Cite

Use of aspirin associates with longer primary patency of hemodialysis grafts.

Journal Article J Am Soc Nephrol · April 2011 Extended-release dipyridamole plus low-dose aspirin (ERDP/ASA) prolongs primary unassisted graft patency of newly created hemodialysis arteriovenous grafts, but the individual contributions of each component are unknown. Here, we analyzed whether use of as ... Full text Link to item Cite

Treatment of chronic hyponatremia: now we know how, but do we know when or if?

Journal Article J Am Soc Nephrol · April 2010 Featured Publication Full text Link to item Cite

Effect of dipyridamole plus aspirin on hemodialysis graft patency.

Journal Article N Engl J Med · May 21, 2009 Featured Publication BACKGROUND: Arteriovenous graft stenosis leading to thrombosis is a major cause of complications in patients undergoing hemodialysis. Procedural interventions may restore patency but are costly. Although there is no proven pharmacologic therapy, dipyridamo ... Full text Link to item Cite

Primer on Kidney Diseases

Book · January 1, 2009 This official publication of the National Kidney Foundation (NKF) covers all aspects of adult and pediatric kidney diseases and is ideal for nephrologists and non-nephrologists alike. The full-color design, high-quality photographs, and outstanding graphs ... Cite

Urinalysis

Chapter · January 1, 2009 Full text Cite

When is it appropriate to use vasopressin receptor antagonists?

Journal Article J Am Soc Nephrol · June 2008 Featured Publication Hyponatremia is a common and challenging disorder. The mainstays of treatment until recently were water restriction and hypertonic saline. The first nonpeptide vasopressin receptor antagonist (VRA) is now approved by the US Food and Drug Administration for ... Full text Link to item Cite

Effect of clopidogrel on early failure of arteriovenous fistulas for hemodialysis: a randomized controlled trial.

Journal Article JAMA · May 14, 2008 Featured Publication CONTEXT: The arteriovenous fistula is the preferred type of vascular access for hemodialysis because of lower thrombosis and infection rates and lower health care expenditures compared with synthetic grafts or central venous catheters. Early failure of fis ... Full text Link to item Cite

Tolvaptan, an oral vasopressin V2 receptor antagonist for heart failure?

Journal Article Am J Kidney Dis · December 2007 Featured Publication Full text Link to item Cite

Hyponatremia treatment guidelines 2007: expert panel recommendations.

Journal Article Am J Med · November 2007 Featured Publication Although hyponatremia is a common, usually mild, and relatively asymptomatic disorder of electrolytes, acute severe hyponatremia can cause substantial morbidity and mortality, particularly in patients with concomitant disease. In addition, overly rapid cor ... Full text Link to item Cite

Familial hypocalciuric hypercalcemia in the donor and recipient of a living related donor kidney transplant.

Journal Article Am J Transplant · March 2007 Featured Publication Familial hypocalciuric hypercalcemia (FHH) is caused by heterozygous inactivation of the calcium-sensing receptor, which is notably expressed in parathyroid and kidney. FHH is characterized by asymptomatic hypercalcemia and hypophosphatemia and confers min ... Full text Link to item Cite

Postinfectious glomerulonephritis in renal allograft recipients.

Journal Article Transplantation · November 15, 2006 Featured Publication Postinfectious glomerulonephritis (PIGN) is a rare etiology of de novo glomerulonephritis following kidney transplantation. To date, there have only been eight cases reported in the literature. We report an additional three patients transplanted at our ins ... Full text Link to item Cite

Vasopressin receptor antagonists.

Journal Article Kidney Int · June 2006 Featured Publication The first non-peptide vasopressin receptor antagonist (VRA) was recently approved by the United States Food and Drug Administration, and several others are now in late stages of clinical development. Phase 3 trials indicate that these agents predictably re ... Full text Link to item Cite

Kidney disease other than renal crisis in patients with diffuse scleroderma.

Journal Article J Rheumatol · April 2005 Featured Publication OBJECTIVE: To determine the frequency and severity of kidney abnormalities in patients with diffuse scleroderma. METHODS: All patients with diffuse scleroderma seen at the University of Pittsburgh between 1972 and 1993 were included in the study. Kidney fu ... Link to item Cite

Intravenous immunoglobulin and plasmapheresis in acute humoral rejection: experience in renal allograft transplantation.

Journal Article Hum Immunol · April 2005 Featured Publication Acute humoral rejection (AHR) in kidney transplantation is associated with higher rates of allograft loss when compared with acute cellular rejection (ACR). Treatment with intravenous immunoglobulin (IVIG) combined with plasmapheresis (PP) has been used re ... Full text Link to item Cite

Hyperkalemia: a review.

Journal Article J Intensive Care Med · 2005 Featured Publication Potassium is the principal intracellular cation, and maintenance of the distribution of potassium between the intracellular and the extracellular compartments relies on several homeostatic mechanisms. When these mechanisms are perturbed, hypokalemia or hyp ... Full text Link to item Cite

Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejection.

Journal Article Transplantation · May 15, 2003 BACKGROUND: Acute humoral rejection (AHR) has been associated with enhanced graft loss. Our study compared the renal allograft survival of patients with AHR treated with plasmapheresis (PP) and intravenous immunoglobulin (IVIG) with allograft survival in p ... Full text Link to item Cite

Effect of home monitoring on blood pressure and left ventricular hypertrophy in a hemodialysis cohort.

Journal Article JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY · September 1, 2002 Link to item Cite

Thyroid hormone in the treatment of post-transplant acute tubular necrosis (ATN).

Journal Article American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · January 2002 Delayed graft function (DGF) in cadaver kidney transplants is a common problem and is often due to acute tubular necrosis (ATN). DGF in transplants may have a deleterious effect on long-term graft survival. Since thyroid hormone has been shown to hasten re ... Full text Cite

Viral infections after renal transplantation.

Journal Article Am J Kidney Dis · April 2001 Viral infections are a leading cause of posttransplantation morbidity and mortality. A number of recent developments have altered our understanding and management of these disorders. The pathogenetic roles of several viruses, including human herpesviruses ... Full text Link to item Cite

Factors influencing function of temporary dialysis catheters.

Journal Article Clin Nephrol · March 2000 AIM: To determine risk factors for failure of temporary dialysis catheters, we prospectively studied the outcome of 178 non-tunneled dual lumen catheters placed in 126 consecutive patients requiring treatment of acute renal failure (ARF) or end-stage renal ... Link to item Cite

Factors affecting system clotting in continuous renal replacement therapy: results of a randomized, controlled trial.

Journal Article Clin Nephrol · January 2000 BACKGROUND: System clotting and the anticoagulation techniques employed to prevent it are important causes of morbidity in continuous renal replacement therapy (CRRT). Different means have been employed in attempts to prolong system lifespan while minimizi ... Link to item Cite

A trial of thyroxine in acute renal failure.

Journal Article Kidney Int · January 2000 UNLABELLED: A trial of thyroxine in acute renal failure. BACKGROUND: Acute renal failure (ARF) remains a serious medical problem with a high mortality rate. Efforts to shorten the course of ARF might reduce this mortality. Since thyroxine has been shown in ... Full text Link to item Cite

Diuretic complications.

Journal Article Am J Med Sci · January 2000 Featured Publication BACKGROUND: Diuretics are widely used and generally safe, but like any therapeutic agents, they may cause side effects. METHODS: A review of recent literature pertaining to diuretic usage was performed, with emphasis on specific reports of side effects. Re ... Link to item Cite

Case 24-1998: cholesterol atheroembolism.

Journal Article N Engl J Med · December 17, 1998 Full text Link to item Cite

Hyperkalemia in hospitalized patients: causes, adequacy of treatment, and results of an attempt to improve physician compliance with published therapy guidelines.

Journal Article Arch Intern Med · April 27, 1998 Featured Publication BACKGROUND: Hyperkalemia is a common, potentially life-threatening disorder. Electrocardiograms are considered to be sensitive indicators of the presence of hyperkalemia. Since the treatment of hyperkalemia involves relatively few maneuvers and because its ... Full text Link to item Cite

Hyperkalemia: treatment options.

Journal Article Semin Nephrol · January 1998 Although extracellular potassium accounts for only 1% to 2% of total body potassium, its concentration, [K+], is critical because it affects the depolarization of electrically excitable tissues such as heart and skeletal muscle. Renal failure is a predispo ... Link to item Cite

Acute renal failure in recipients of organ transplantation and nontransplantation patients: comparison of characteristics and mortality.

Journal Article Ren Fail · May 1997 Mortality from acute renal failure in critically ill patients remains in excess of 50% despite decades of improvement in supportive care. It is not known whether replacement of other failing organs by non-renal organ transplantation affects mortality in ac ... Full text Link to item Cite

Focal segmental glomerulosclerosis associated with nephrotic syndrome in cholesterol atheroembolism: clinicopathological correlations.

Journal Article Am J Kidney Dis · March 1997 To better characterize the heavy proteinuria occasionally described in cholesterol atheroembolic renal disease (CAE), we reviewed the clinical features and histological findings of 24 patients found at renal biopsy to have CAE. Twelve (50%) had a typical c ... Full text Link to item Cite

Pregnancy outcomes in a prospective matched control study of pregnancy and renal disease.

Journal Article Clin Nephrol · February 1996 OBJECTIVE: Assessment and comparison of pregnancy outcomes in women with renal disease and women with high risk pregnancies due to medical illness without renal disease. DESIGN: A prospective, matched controlled study. SETTING: The High Risk Obstetrical Cl ... Link to item Cite

Hypernatremia in hospitalized patients.

Journal Article Ann Intern Med · January 15, 1996 Featured Publication OBJECTIVE: To determine the incidence, clinical characteristics, and outcome for general medical-surgical hospital patients with hypernatremia. DESIGN: A prospective cohort study. SETTING: A 942-bed urban university hospital. PATIENTS: All patients who dev ... Full text Link to item Cite

Failure of low molecular weight dextran to prevent clotting during continuous renal replacement therapy.

Journal Article ASAIO J · 1995 Clotting of the extracorporeal circuit during continuous renal replacement therapy results in decreased ultrafiltration rates, impaired solute clearance and, ultimately, occlusion of the extracorporeal circuit. The authors conducted an open-label randomize ... Link to item Cite

Assessment of renal function during pregnancy using a random urine protein to creatinine ratio and Cockcroft-Gault formula.

Journal Article Am J Kidney Dis · September 1994 The current standard for assessment of renal function in pregnant women is a 24-hour urine collection to determine creatinine clearance and proteinuria. It is easier to use the random urine protein to creatinine (P:C) ratio and the Cockcroft-Gault (CG) for ... Full text Link to item Cite

Hemoperitoneum complicating chronic peritoneal dialysis: single-center experience and literature review.

Journal Article Am J Kidney Dis · March 1992 Featured Publication Hemoperitoneum is a well-recognized, if uncommon, complication of chronic peritoneal dialysis. In this review of 424 patients maintained on peritoneal dialysis at a single center during an 11-year period, 26 patients (6.1%) developed one or more episodes o ... Full text Link to item Cite

Dialysate and blood flow dependence of diffusive solute clearance during CVVHD.

Journal Article ASAIO J · 1992 To define the flow dependence of diffusive solute clearance (Kd) during continuous venovenous hemodiafiltration (CVVHD), urea, creatinine, and phosphate clearance were measured during CVVHD, while ultrafiltration was minimized. Studies were performed using ... Full text Link to item Cite

Resolution of cirrhotic glomerulonephritis following successful liver transplantation

Journal Article Clinical Nephrology · 1991 A 38-year-old man with liver failure due to Laennec's cirrhosis developed nephrotic range proteinuria and hematuria. Renal biopsy showed membranoproliferative glomerulonephritis with 2+ staining for IgA and complement consistent with cirrhotic glomerulonep ... Cite

Cyclosporine nephrotoxicity in cardiac allograft patients--a seven-year follow-up.

Journal Article Transplantation · October 1990 Featured Publication Renal function was observed retrospectively in a population of 228 adults who underwent a cardiac allograft at the University of Pittsburgh from June 1980 through June 1987, survived a minimum of one year, and received cyclosporine. Renal function was dete ... Full text Link to item Cite

Biological monitoring for occupational cadmium exposure: the urinary metallothionein.

Journal Article Toxicology · July 1990 The relationship between urinary metallothionein and kidney and liver cadmium levels was examined in 68 active and retired smelter workers. Metallothionein was analyzed by a radioimmunoassay and liver and kidney cadmium levels were determined by in vivo ne ... Full text Link to item Cite

Hyperkalemia associated with intravenous labetalol therapy for acute hypertension in renal transplant recipients.

Journal Article Clin Nephrol · June 1990 Three renal transplant recipients developed potentially life-threatening hyperkalemia after receiving intravenous labetalol for postoperative hypertension. Even as beta-adrenergic agonists find increasing use in the therapy of acute hyperkalemia, physician ... Link to item Cite

Renal failure in cardiac transplantation.

Journal Article Cardiovasc Clin · 1990 Link to item Cite

Atheroembolic involvement of renal allografts.

Journal Article Am J Kidney Dis · April 1989 Renal atheroembolism is a well-recognized cause of renal insufficiency. Two renal allograft recipients with cholesterol atheroemboli in their allograft biopsies are described. In one patient, the origin of the atheroemboli was the recipient aorta while in ... Full text Link to item Cite

Hypercalcemia in patients with advanced chronic renal failure not yet requiring dialysis.

Journal Article Am J Nephrol · 1989 Six patients with progressive chronic renal failure not yet requiring dialysis and not consuming supplemental calcium or vitamin D developed hypercalcemia. Three had proven and 1 suspected tertiary hyperparathyroidism, 1 parathyroid carcinoma and 1 aplasti ... Full text Link to item Cite

Hyperparathyroidism and 1,25-dihydroxyvitamin D deficiency in mild, moderate, and severe renal failure.

Journal Article J Clin Endocrinol Metab · November 1988 It has been postulated that hyperparathyroidism in chronic renal failure results from hypocalcemia, occurring, in part, from phosphate retention and/or deficient 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] synthesis. However, many studies have failed to demons ... Full text Link to item Cite

Chronic effects of nitrendipine on renal hemodynamics and tubular transport.

Journal Article Clin Pharmacol Ther · January 1988 The effects of nitrendipine (10 mg, during acute clearance experiments) given both acutely and after 2 weeks of administration were examined in normal and hypertensive subjects. At the initiation of therapy, nitrendipine caused an increase in glomerular fi ... Full text Link to item Cite

Variant of Bartter's syndrome with a distal tubular rather than loop of Henle defect.

Journal Article Nephron · 1988 Featured Publication A 19-year-old normotensive patient had all of the clinical features of Bartter's syndrome: hypokalemia, elevated renin and aldosterone levels and increased excretion of prostaglandin E. In contrast to the patients described by Bartter, the patient had a no ... Full text Link to item Cite

Hypercalcemia. A complication of advanced chronic liver disease.

Journal Article Arch Intern Med · February 1987 Hypercalcemia has not previously been recognized as a complication of advanced chronic liver disease without hepatoma. During a five-year period, 16 patients evaluated in the liver transplantation program at the University of Pittsburgh developed hypercalc ... Full text Link to item Cite

Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.

Journal Article Am J Kidney Dis · January 1987 Featured Publication To characterize the two forms of cyclosporine nephrotoxicity, we examined renal function in the immediate and late postoperative periods after cardiac transplantation. Moderate azotemia occurred during the first postoperative week in 58% of 43 cyclosporine ... Full text Link to item Cite

Acute renal failure due to high-grade obstruction following therapy with epsilon-aminocaproic acid.

Journal Article Am J Kidney Dis · December 1986 An 18-year-old man with mild factor VIII deficiency developed hematuria and, subsequently, acute renal failure due to high-grade urinary obstruction by clots during therapy with cryoprecipitate, epsilon-aminocaproic acid, and acetazolamide administered for ... Full text Link to item Cite

Serum electrolyte patterns in end-stage renal disease.

Journal Article Am J Kidney Dis · August 1986 The charts of 70 successive patients presenting for dialysis therapy for end-stage renal disease (ESRD) were evaluated for their serum electrolyte values. The "classical" pattern of low total CO2 (tCO2), elevated anion gap ("delta"), and normal chloride wa ... Full text Link to item Cite

What's new in diuretic therapy.

Journal Article Am Fam Physician · May 1986 Link to item Cite

Spontaneous hypercalcemia in patients undergoing dialysis. Etiologic and therapeutic considerations.

Journal Article Am J Med · April 1986 Ten dialysis-treated patients with hypercalcemia (11.5 +/- 0.3 mg/dl, mean +/- SE) due to renal osteodystrophy were compared with 30 control dialysis-treated patients who were not hypercalcemic (9.5 +/- 0.1 mg/dl). The hypercalcemic patients were more disa ... Full text Link to item Cite

In vivo bone lead measurements: a rapid monitoring method for cumulative lead exposure.

Journal Article Am J Ind Med · 1986 Lead concentrations (microgram/g wet weight) in human bone (tibia) were measured noninvasively in vivo employing an X-ray fluorescence technique. Forty-five workers who had been subjected to chronic industrial exposure were found to have a mean bone lead c ... Full text Link to item Cite

Cholesterol atheroembolic renal disease. Report of 3 cases with emphasis on diagnosis by skin biopsy and extended survival.

Journal Article Am J Nephrol · 1986 Because antemortem diagnosis is difficult, renal failure due to cholesterol atheroembolism has, until recently, been regarded as a uniformly irreversible and generally fatal disease. Of late, recovery of renal function in several patients in whom the diagn ... Full text Link to item Cite

Effects of elevated lead and cadmium burdens on renal function and calcium metabolism.

Journal Article Arch Environ Health · 1986 To assess the pathophysiologic significance of increased body burdens of lead and cadmium, detailed renal function studies and evaluation of calcium, phosphorus, and vitamin D metabolism were carried out in 38 industrial workers exposed to lead and cadmium ... Full text Link to item Cite

Renal hemodynamic and tubular transport effects of nitrendipine.

Journal Article J Lab Clin Med · April 1985 Nitrendipine, a 1,4-dihydropyridine derivative, is a new calcium entry blocker with marked antihypertensive effects. Because relatively few data are available regarding its renal effects, we studied the drug's action on renal hemodynamics and electrolyte e ... Link to item Cite

Combined effect of bumetanide and metolazone in normal volunteers.

Journal Article J Clin Pharmacol · 1985 Bumetanide 1 to 2 mg or metolazone 2.5 mg were administered by mouth separately and then in combination to eight normal men and women in order to determine whether a sequential blockade of sodium reabsorption with diuretic agents that act at different site ... Full text Link to item Cite

Renal hemodynamic and tubular transport effects of nitrendipine

Journal Article The Journal of Laboratory and Clinical Medicine · 1985 Nitrendipine, a 1,4-dihydropyridine derivative, is a new calcium entry blocker with marked antihypertensive effects. Because relatively few data are available regarding its renal effects, we studied the drug's action on renal hemodynamics and electrolyte e ... Cite

Acute renal failure due to perirenal hematoma complicating open renal biopsy.

Journal Article J Urol · November 1984 Diminished renal concentration and excretion of intravenous radiographic contrast medium are cardinal findings in perirenal hematoma. However, despite a high incidence of perirenal hematoma after renal biopsy acute renal failure has not been described in t ... Full text Link to item Cite

Severe theophylline toxicity. Role of conservative measures, antiarrhythmic agents, and charcoal hemoperfusion.

Journal Article Am J Med · May 1984 The presenting symptoms, course, and treatment of 10 patients with severe theophylline toxicity (heart rate above 120, multifocal atrial tachycardia or premature ventricular contractions, hypotension, seizures) are described. Theophylline levels at present ... Full text Link to item Cite

Renal failure in heart transplant patients receiving cyclosporine

Journal Article Transplantation Proceedings · 1983 Cite

Effects of two models of hypercalcemia on renal acid base metabolism.

Journal Article Kidney Int · April 1982 The effects of two models of chronic hypercalcemia on renal acid-base metabolism were studied in rats. In the first series of experiments, rats were rendered hyperparathyroid by the autologous grafting of 20 to 24 parathyroid glands into a single recipient ... Full text Link to item Cite

Effects of two nonsteroidal anti-inflammatory drugs, indomethacin and oxaprozin, on the kidney.

Journal Article Clin Pharmacol Ther · November 1980 Nonsteroidal anti-inflammatory drugs (NSAIDs) have been found to cause sodium retention and to decrease glomerular filtration rate (GFR). We studied the effects of two such drugs, indomethacin and oxaprozin, a new propionic acid derivative, on renal functi ... Full text Link to item Cite