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Serum electrolyte patterns in end-stage renal disease.

Publication ,  Journal Article
Wallia, R; Greenberg, A; Piraino, B; Mitro, R; Puschett, JB
Published in: Am J Kidney Dis
August 1986

The charts of 70 successive patients presenting for dialysis therapy for end-stage renal disease (ESRD) were evaluated for their serum electrolyte values. The "classical" pattern of low total CO2 (tCO2), elevated anion gap ("delta"), and normal chloride was found in a minority of patients (14 of 70, or 20%). Hyperchloremia was noted in 46%; in 21 patients (30%), this was associated with a normal delta and in 11 (16%), hyperchloremia was accompanied by an elevated delta. Fourteen patients (20%), most with diabetic nephropathy, had normal serum electrolytes. Patients with chronic glomerulonephritis had a hyperchloremic pattern as often as not, and two of four patients with interstitial nephritis demonstrated hyperchloremia without an elevated delta. We conclude that the previously held thesis that hyperchloremia is a rare or absent finding by the time renal failure progresses to ESRD is no longer tenable. Furthermore, a significant minority of ESRD patients may require the initiation of dialysis at a time when their serum electrolytes are still normal.

Duke Scholars

Published In

Am J Kidney Dis

DOI

ISSN

0272-6386

Publication Date

August 1986

Volume

8

Issue

2

Start / End Page

98 / 104

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Sodium
  • Potassium
  • Middle Aged
  • Male
  • Kidney Failure, Chronic
  • Humans
  • Glomerulonephritis
  • Female
  • Electrolytes
 

Citation

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Wallia, R., Greenberg, A., Piraino, B., Mitro, R., & Puschett, J. B. (1986). Serum electrolyte patterns in end-stage renal disease. Am J Kidney Dis, 8(2), 98–104. https://doi.org/10.1016/s0272-6386(86)80119-6
Wallia, R., A. Greenberg, B. Piraino, R. Mitro, and J. B. Puschett. “Serum electrolyte patterns in end-stage renal disease.Am J Kidney Dis 8, no. 2 (August 1986): 98–104. https://doi.org/10.1016/s0272-6386(86)80119-6.
Wallia R, Greenberg A, Piraino B, Mitro R, Puschett JB. Serum electrolyte patterns in end-stage renal disease. Am J Kidney Dis. 1986 Aug;8(2):98–104.
Wallia, R., et al. “Serum electrolyte patterns in end-stage renal disease.Am J Kidney Dis, vol. 8, no. 2, Aug. 1986, pp. 98–104. Pubmed, doi:10.1016/s0272-6386(86)80119-6.
Wallia R, Greenberg A, Piraino B, Mitro R, Puschett JB. Serum electrolyte patterns in end-stage renal disease. Am J Kidney Dis. 1986 Aug;8(2):98–104.
Journal cover image

Published In

Am J Kidney Dis

DOI

ISSN

0272-6386

Publication Date

August 1986

Volume

8

Issue

2

Start / End Page

98 / 104

Location

United States

Related Subject Headings

  • Urology & Nephrology
  • Sodium
  • Potassium
  • Middle Aged
  • Male
  • Kidney Failure, Chronic
  • Humans
  • Glomerulonephritis
  • Female
  • Electrolytes