Overview
Education and Training
2009-2015 Ph.D. Vanderbilt University, Department of Molecular Physiology and Biophysics
Major: Molecular Physiology
Advisor: Dr. David H. Wasserman, Department of Molecular Physiology and Biophysics
Dissertation title: Integrin Signaling is a Novel Regulator of Hepatic Insulin Action
2007-2009 M.S. Appalachian State University, Department of Biology
Major: Biology, Minor: Exercise Science
Advisor: Dr. Dru Henson, Department of Biology
Thesis title: Quercetin’s Influence on Exercise Performance and Muscle Mitochondrial
Biogenesis in Untrained Individuals
2000-2005 B.S. Appalachian State University, Department of Biology
Major: Pre-professional Biology
Current Appointments & Affiliations
Research Associate, Senior
Duke Molecular Physiology Institute,
Institutes and Centers
Recent Publications
Ketogenesis protects against MASLD-MASH progression through mechanisms that extend beyond overall fat oxidation rate.
Journal Article bioRxiv · December 21, 2024 The progression of metabolic-dysfunction-associated steatotic liver disease (MASLD) to metabolic-dysfunction-associated steatohepatitis (MASH) involves complex alterations in both liver-autonomous and systemic metabolism that influence the liver's balance ... Full text Link to item CiteKetone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding.
Journal Article Cell Metab · February 6, 2024 Time-restricted feeding (TRF) has gained attention as a dietary regimen that promotes metabolic health. This study questioned if the health benefits of an intermittent TRF (iTRF) schedule require ketone flux specifically in skeletal and cardiac muscles. No ... Full text Link to item CiteCirculating Metabolites Associated with Albuminuria in a Hispanic/Latino Population.
Journal Article Clin J Am Soc Nephrol · February 1, 2023 BACKGROUND: Albuminuria is associated with metabolic abnormalities, but these relationships are not well understood. We studied the association of metabolites with albuminuria in Hispanic/Latino people, a population with high risk for metabolic disease. ME ... Full text Link to item CiteRecent Grants
Mechanisms of lipid-induced bioenergetic stress in muscle
ResearchResearch Associate · Awarded by National Institutes of Health · 2010 - 2028Role of Muscle Ketone Metabolism in Mediating the Metabolic Benefits of Weight Loss
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025Ketone Body Metabolism and Integrated Metabolic Homeostasis
ResearchPostdoctoral Associate · Awarded by University of Minnesota · 2020 - 2025View All Grants