https://orcid.org/0000-0003-1960-8385
Recent Scholarly Works
Radical S-Adenosyl-l-Methionine Oxygenase DarE Forms Ether Bond via a Partially Delocalized Tryptophan Cβ Radical.
Journal article J Am Chem Soc · February 4, 2026 Darobactins are ribosomally synthesized and post-translationally modified peptides (RiPPs) with potent activity against Gram-negative pathogens. Their antibiotic function depends on a distinctive β-strand architecture stabilized by an ether cross-link betw ... Full text Link to item CiteRadical-Mediated Nucleophilic Peptide Cross-Linking in Dynobactin Biosynthesis.
Journal article J Am Chem Soc · November 20, 2024 Dynobactins are recently discovered ribosomally synthesized and post-translationally modified peptide (RiPP) antibiotics that selectively kill Gram-negative pathogens by inhibiting the β-barrel assembly machinery (Bam) located on their outer membranes. Suc ... Full text Link to item CiteRecent Grants
Supporting a highly successful graduate student working on cofactor and natural product biosynthesis
FellowshipPI-Fellow · Awarded by American Chemical Society · 2025 - 2026Radical-mediated biosynthesis and discovery of peptide antibiotics
FellowshipPI-Fellow · Awarded by American Heart Association · 2024 - 2025Mechanism of carbon skeleton formation in molybdenum cofactor biosynthesis
ResearchGraduate Student · Awarded by National Institutes of Health · 2020 - 2025View All Grants