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Connie Watkins Bales

Professor Emeritus in Medicine
Medicine, Geriatrics and Palliative Care
Duke Box 3003, Durham, NC 27710
2508 Busse Bldg, Durham, NC 27710

Overview


Research in our laboratory focuses on the role of nutrition (particularly vitamins and minerals) in the prevention and management of chronic diseases in older adults. Previous studies have concerned trace elements and cardiovascular disease, calcium and osteoporosis, and renal synthesis of vitamin D as it relates to bone health. Some of our newest work emphasizes the role of micronutrients as antioxidants and their interaction with the aging process. We are also working on various aspects of energy balance in older adults, ranging from failure to thrive in stroke patients with dysphagia to exercise and nutrition effects in overweight subjects who begin physical training. Thus we have a number of clinical and epidemiological projects on-going, many of which include a strong emphasis on nutrition assessment techniques in middle-aged and elderly subjects.

Current Duke Appointments & Affiliations


Professor Emeritus in Medicine · 2024 - Present Medicine, Geriatrics and Palliative Care, Medicine
Senior Fellow in the Center for the Study of Aging and Human Development · 1988 - Present Center for the Study of Aging and Human Development, Institutes and Centers

Recent Scholarly Works


Influence of Protein Intake during Obesity Reduction on Physical Function and Body Habitus in Older Males with Prediabetes: A Pilot Study.

Journal article Curr Dev Nutr · September 2026 BACKGROUND: Weight loss can improve health and function in older adults with obesity but may also accelerate loss of fat-free mass. Older men are underrepresented in obesity intervention trials; thus we tested higher protein intake plus exercise to help pr ... Full text Link to item Cite

Inflammation hinders anabolic potential of nutritional support in cancer: findings from the Protein Recommendation to Increase Muscle (PRIMe) trial.

Journal article Am J Clin Nutr · August 10, 2026 BACKGROUND: Our recent Protein Recommendation to Increase Muscle (PRIMe) trial suggested that increasing daily protein intake via nutrition counseling in patients with colorectal cancer positively impacts muscle mass. OBJECTIVES: This post hoc analysis inv ... Full text Link to item Cite

Nutrition for Older Adults: Perspectives on Dietary Guidance for Healthy Aging.

Journal article Curr Dev Nutr · March 2026 The world is rapidly aging. It is projected that the "young old" (i.e., 60+ y) population will double by 2050 and the "older old" (i.e., 80+ y) will nearly triple. Greater life expectancy has been accompanied by more chronic health conditions and disabilit ... Full text Link to item Cite
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Recent Grants


Obesity, cartilage mechanics, and joint health

ResearchCo Investigator · Awarded by National Institutes of Health · 2026 - 2031

Weight loss, in vivo cartilage mechanics, and joint health

ResearchCo Investigator · Awarded by National Institutes of Health · 2019 - 2025

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Education


University of Tennessee, Knoxville · 1981 Ph.D.