Barry W. Allen

Employing the techniques of analytical electrochemistry, in vitro and in vivo, to elucidate the physiological roles of diffusible signaling molecules in brain, in other excitable tissues, and in blood. Such molecules include Ca++, NO·, and CO.

Current Appointments & Affiliations

Adjunct Assistant Professor in the Department of Anesthesiology · 2017 - Present Anesthesiology, Clinical Science Departments

Recent Publications

Nonfunctional Missense Mutants in Two Well Characterized Cytosolic Enzymes Reveal Important Information About Protein Structure and Function.

Journal Article Protein J · October 2018 The isolation and characterization of 42 unique nonfunctional missense mutants in the bacterial cytosolic β-galactosidase and catechol 2,3-dioxygenase enzymes allowed us to examine some of the basic general trends regarding protein structure and function. ... Full text Link to item Cite

Engineered cardiac tissue patch maintains structural and electrical properties after epicardial implantation.

Journal Article Biomaterials · March 2018 Functional cardiac tissue engineering holds promise as a candidate therapy for myocardial infarction and heart failure. Generation of "strong-contracting and fast-conducting" cardiac tissue patches capable of electromechanical coupling with host myocardium ... Full text Link to item Cite

Cardiopatch platform enables maturation and scale-up of human pluripotent stem cell-derived engineered heart tissues.

Journal Article Nat Commun · November 28, 2017 Despite increased use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) for drug development and disease modeling studies, methods to generate large, functional heart tissues for human therapy are lacking. Here we present a "Cardiop ... Full text Link to item Cite

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Recent Grants

Critical Molecular Targets for the Toxic Effects of Hyperbaric Oxygen and a Novel Pharmacological Approach for Preventing Acute Toxicity

ResearchAdjunct Investigator · Awarded by Office of Naval Research · 2011 - 2019

Neurogenic Mechanisms in CNS and Pulmonary Oxygen Toxicity

ResearchAdjunct Investigator · Awarded by Office of Naval Research · 2003 - 2010

Nitric Oxide and CNS-Pulmonary Interactions in 02 Toxicity

ResearchAdjunct Investigator · Awarded by Office of Naval Research · 2003 - 2007

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Education, Training & Certifications

Duke University · 1984 Ph.D.