Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Post-Doctoral Associate, Biochemistry, Duke University 2007 - 2010
  • Ph.D., Duke University 2007
• 

  Duke Appointment History

  • Assistant Research Professor in Biology, Biology, Trinity College of Arts & Sciences 2015 - 2016
  • Instructor, Temporary in the Department of Biochemistry, Biochemistry, Basic Science Departments 2010
• Recognition
• 

  In the News

  • OCT 8, 2013

    Durham Herald-Sun

    The organists: Behind the sounds of Duke Chapel
• Research
• 

  External Relationships

  • PhD Posters, LLC
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Wu, Qinglin, Brian E. Coggins, and Pei Zhou. “Unbiased measurements of reconstruction fidelity of sparsely sampled magnetic resonance spectra.” Nat Commun 7 (July 27, 2016): 12281. https://doi.org/10.1038/ncomms12281.
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    • Reardon, P. N., C. L. Marean-Reardon, M. A. Bukovec, B. E. Coggins, and N. G. Isern. “3D TOCSY-HSQC NMR for Metabolic Flux Analysis Using Non-Uniform Sampling.” Anal Chem 88, no. 5 (March 1, 2016): 2825–31. https://doi.org/10.1021/acs.analchem.5b04535.
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    • Coggins, Brian E., Jonathan W. Werner-Allen, Anthony Yan, and Pei Zhou. “Rapid protein global fold determination using ultrasparse sampling, high-dynamic range artifact suppression, and time-shared NOESY.” J Am Chem Soc 134, no. 45 (November 14, 2012): 18619–30. https://doi.org/10.1021/ja307445y.
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    • Coggins, Brian E., Ronald A. Venters, and Pei Zhou. “Radial sampling for fast NMR: Concepts and practices over three decades.” Prog Nucl Magn Reson Spectrosc 57, no. 4 (November 2010): 381–419. https://doi.org/10.1016/j.pnmrs.2010.07.001.
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    • Werner-Allen, Jon W., Brian E. Coggins, and Pei Zhou. “Fast acquisition of high resolution 4-D amide-amide NOESY with diagonal suppression, sparse sampling and FFT-CLEAN.” J Magn Reson 204, no. 1 (May 2010): 173–78. https://doi.org/10.1016/j.jmr.2010.02.017.
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    • Coggins, Brian E., and Pei Zhou. “High resolution 4-D spectroscopy with sparse concentric shell sampling and FFT-CLEAN.” J Biomol Nmr 42, no. 4 (December 2008): 225–39. https://doi.org/10.1007/s10858-008-9275-x.
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    • Coggins, Brian E., and Pei Zhou. “Sampling of the NMR time domain along concentric rings.” J Magn Reson 184, no. 2 (February 2007): 207–21. https://doi.org/10.1016/j.jmr.2006.10.002.
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    • Coggins, Brian E., and Pei Zhou. “Polar Fourier transforms of radially sampled NMR data.” J Magn Reson 182, no. 1 (September 2006): 84–95. https://doi.org/10.1016/j.jmr.2006.06.016.
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    • Coggins, Brian E., and Pei Zhou. “PR-CALC: a program for the reconstruction of NMR spectra from projections.” J Biomol Nmr 34, no. 3 (March 2006): 179–95. https://doi.org/10.1007/s10858-006-0020-z.
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    • Coggins, Brian E., Ronald A. Venters, and Pei Zhou. “Filtered backprojection for the reconstruction of a high-resolution (4,2)D CH3-NH NOESY spectrum on a 29 kDa protein.” J Am Chem Soc 127, no. 33 (August 24, 2005): 11562–63. https://doi.org/10.1021/ja053110k.
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    • Jiang, Ling, Brian E. Coggins, and Pei Zhou. “Rapid assignment of protein side chain resonances using projection-reconstruction of (4,3)D HC(CCO)NH and intra-HC(C)NH experiments.” J Magn Reson 175, no. 1 (July 2005): 170–76. https://doi.org/10.1016/j.jmr.2005.03.014.
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    • Venters, Ronald A., Brian E. Coggins, Doug Kojetin, John Cavanagh, and Pei Zhou. “(4,2)D Projection--reconstruction experiments for protein backbone assignment: application to human carbonic anhydrase II and calbindin D(28K).” J Am Chem Soc 127, no. 24 (June 22, 2005): 8785–95. https://doi.org/10.1021/ja0509580.
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    • Coggins, Brian E., Amanda L. McClerren, Ling Jiang, Xuechen Li, Johannes Rudolph, Ole Hindsgaul, Christian R. H. Raetz, and Pei Zhou. “Refined solution structure of the LpxC-TU-514 complex and pKa analysis of an active site histidine: insights into the mechanism and inhibitor design.” Biochemistry 44, no. 4 (February 1, 2005): 1114–26. https://doi.org/10.1021/bi047820z.
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    • Coggins, Brian E., Ronald A. Venters, and Pei Zhou. “Generalized reconstruction of n-D NMR spectra from multiple projections: application to the 5-D HACACONH spectrum of protein G B1 domain.” J Am Chem Soc 126, no. 4 (February 4, 2004): 1000–1001. https://doi.org/10.1021/ja039430q.
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    • Coggins, Brian E., Xuechen Li, Ole Hindsgaul, Christian R. H. Raetz, and Pei Zhou. “Assignment of the 1H, 13C and 15N resonances of the LpxC deacetylase from Aquifex aeolicus in complex with the substrate-analog inhibitor TU-514.” J Biomol Nmr 28, no. 2 (February 2004): 201–2. https://doi.org/10.1023/B:JNMR.0000013817.29493.87.
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    • Coggins, Brian E., Xuechen Li, Amanda L. McClerren, Ole Hindsgaul, Christian R. H. Raetz, and Pei Zhou. “Structure of the LpxC deacetylase with a bound substrate-analog inhibitor.” Nat Struct Biol 10, no. 8 (August 2003): 645–51. https://doi.org/10.1038/nsb948.
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    • Coggins, Brian E., and Pei Zhou. “PACES: Protein sequential assignment by computer-assisted exhaustive search.” J Biomol Nmr 26, no. 2 (June 2003): 93–111. https://doi.org/10.1023/a:1023589029301.
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  • Book Sections

    • Coggins, B. E., and P. Zhou. “CLEAN.” In New Developments in NMR, 2017-January:169–219, 2017. https://doi.org/10.1039/9781782628361-00169.
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    • Coggins, B. E., and P. Zhou. “Backprojection and Related Methods.” In New Developments in NMR, 2017-January:119–68, 2017. https://doi.org/10.1039/9781782628361-00119.
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• Teaching & Mentoring
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  Recent Courses

  • BIOCHEM 301: Introductory Biochemistry I: Intermediary Metabolism 2021
  • BIOCHEM 593: Research Independent Study 2021
  • BIOCHEM 301: Introductory Biochemistry I: Intermediary Metabolism 2020
  • BIOCHEM 593: Research Independent Study 2020
  • BIOCHEM 301: Introductory Biochemistry I: Intermediary Metabolism 2019
  • BIOCHEM 593: Research Independent Study 2019

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