Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., McGill University (Canada) 1991
• 

  Duke Appointment History

  • Assistant Professor in Medicine, Neurology, Clinical Science Departments 2006 - 2013
  • Assistant Research Professor of Medicine, Neurology, Clinical Science Departments 2004 - 2006
  • Assistant Research Professor in Pathology, Pathology, Clinical Science Departments 1999 - 2004
  • Instructor, Temporary of Pathology, Pathology, Clinical Science Departments 1999
• Publications & Artistic Works
• 

  Selected Publications

  • Book Sections

    • Bennett, ER, Reuter-Rice, K, and Laskowitz, DT. "Genetic influences in traumatic brain injury." In Translational Research in Traumatic Brain Injury, 179-218. April 21, 2016.

  • Conference Papers

    • Terrell, TR, Bostick, R, Rogers, GL, Langston, MA, Barth, J, Bennett, E, Sloane, R, Galloway, L, Cantu, RC, and Mihelic, FM. "Association of APOE and other genetic polymorphisms with prospective concussion risk in a prospective cohort study of college athletes." January 1, 2014.  Full Text

  • Journal Articles

    • Reuter-Rice, K, Regier, M, Bennett, E, and Laskowitz, D. "The Effect of the Relationship of APOE Polymorphisms and Cerebral Vasospasm on Functional Outcomes in Children With Traumatic Brain Injury." Biological Research for Nursing 20, no. 5 (October 2018): 566-576.  Full Text
    • Laskowitz, DT, Bennett, ER, Durham, RJ, Volpi, JJ, Wiese, JR, Frankel, M, Shpall, E, Wilson, JM, Troy, J, and Kurtzberg, J. "Allogeneic Umbilical Cord Blood Infusion for Adults with Ischemic Stroke: Clinical Outcomes from a Phase I Safety Study." Stem Cells Translational Medicine 7, no. 7 (July 2018): 521-529.  Full Text
    • Xie, Y, Li, Y-J, Lei, B, Kernagis, D, Liu, W-W, Bennett, ER, Venkatraman, T, Lascola, CD, Laskowitz, DT, Warner, DS, and James, ML. "Sex Differences in Gene and Protein Expression After Intracerebral Hemorrhage in Mice." Translational stroke research (May 13, 2018).  Full Text
    • Terrell, TR, Abramson, R, Barth, JT, Bennett, E, Cantu, RC, Sloane, R, Laskowitz, DT, Erlanger, DM, McKeag, D, Nichols, G, Valentine, V, and Galloway, L. "Genetic polymorphisms associated with the risk of concussion in 1056 college athletes: a multicentre prospective cohort study." British journal of sports medicine 52, no. 3 (February 2018): 192-198.  Full Text
    • El Husseini, N, Hoffman, BM, Bennett, ER, Li, Y-W, Williamson Taylor, RA, Hailey, CE, Richardson, K, Li, Y-J, Laskowitz, DT, and James, ML. "Association of IL6ST (gp130) Polymorphism with Functional Outcome Following Spontaneous Intracerebral Hemorrhage." Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 27, no. 1 (January 2018): 125-131.  Full Text
    • Sharma, R, Rosenberg, A, Bennett, ER, Laskowitz, DT, and Acheson, SK. "A blood-based biomarker panel to risk-stratify mild traumatic brain injury." PloS one 12, no. 3 (January 2017): e0173798-.  Full Text
    • Terrell, TR, Bostick, R, Barth, J, Sloane, R, Cantu, RC, Bennett, E, Galloway, L, Laskowitz, D, Erlanger, D, McKeag, D, Valentine, V, and Nichols, G. "Multicenter cohort study on association of genotypes with prospective sports concussion: methods, lessons learned, and recommendations." The Journal of sports medicine and physical fitness 57, no. 1-2 (January 2017): 77-89.  Full Text
    • Berger, M, Nadler, JW, Friedman, A, McDonagh, DL, Bennett, ER, Cooter, M, Qi, W, Laskowitz, DT, Ponnusamy, V, Newman, MF, Shaw, LM, Warner, DS, Mathew, JP, James, ML, and MAD-PIA trial team, . "The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial." Journal of Alzheimer'S Disease : Jad 52, no. 4 (April 2016): 1299-1310.  Full Text  Open Access Copy
    • Reuter-Rice, K, Eads, JK, Berndt, SB, and Bennett, E. "Chapter 6 state of the science of pediatric traumatic brain injury: biomarkers and gene association studies." Annual Review of Nursing Research 33 (January 2015): 185-217. (Review)  Full Text
    • Lindsey, BD, Nicoletto, HA, Bennett, ER, Laskowitz, DT, and Smith, SW. "3-D transcranial ultrasound imaging with bilateral phase aberration correction of multiple isoplanatic patches: a pilot human study with microbubble contrast enhancement." Ultrasound Med Biol 40, no. 1 (January 2014): 90-101.  Full Text  Link to Item
    • Lindsey, BD, Nicoletto, HA, Bennett, ER, Laskowitz, DT, and Smith, SW. "Simultaneous bilateral real-time 3-d transcranial ultrasound imaging at 1 MHz through poor acoustic windows." Ultrasound Med Biol 39, no. 4 (April 2013): 721-734.  Full Text  Link to Item
    • Wang, H, Anderson, LG, Lascola, CD, James, ML, Venkatraman, TN, Bennett, ER, Acheson, SK, Vitek, MP, and Laskowitz, DT. "ApolipoproteinE mimetic peptides improve outcome after focal ischemia." Exp Neurol 241 (March 2013): 67-74.  Full Text  Link to Item
    • Lindsey, BD, Light, ED, Nicoletto, HA, Bennett, ER, Laskowitz, DT, and Smith, SW. "The ultrasound brain helmet: new transducers and volume registration for in vivo simultaneous multi-transducer 3-D transcranial imaging." Ieee Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 58, no. 6 (June 2011): 1189-1202.  Full Text
    • Swaminathan, M, Nicoara, A, Phillips-Bute, BG, Aeschlimann, N, Milano, CA, Mackensen, GB, Podgoreanu, MV, Velazquez, EJ, Stafford-Smith, M, Mathew, JP, and Cardiothoracic Anesthesia Research Endeavors (CARE) Group, . "Utility of a simple algorithm to grade diastolic dysfunction and predict outcome after coronary artery bypass graft surgery." Ann Thorac Surg 91, no. 6 (June 2011): 1844-1850.  Full Text  Link to Item
    • Lindsey, BD, Light, ED, Smith, SW, Nicoletto, HA, Bennett, ER, and Laskowitz, DT. "Dual matrix arrays integrated into scanner for increased SNR of ultrasound brain helmet." Proceedings - IEEE Ultrasonics Symposium (2010): 1100-1103.  Full Text
    • James, ML, Blessing, R, Phillips-Bute, BG, Bennett, E, and Laskowitz, DT. "S100B and brain natriuretic peptide predict functional neurological outcome after intracerebral haemorrhage." Biomarkers 14, no. 6 (September 2009): 388-394.  Full Text  Link to Item
    • James, ML, Blessing, R, Bennett, E, and Laskowitz, DT. "Apolipoprotein E modifies neurological outcome by affecting cerebral edema but not hematoma size after intracerebral hemorrhage in humans." J Stroke Cerebrovasc Dis 18, no. 2 (March 2009): 144-149.  Full Text  Link to Item
    • Lindsey, BD, Ivancevich, NM, Light, ED, Smith, SW, Nicoletto, HA, Bennett, E, and Laskowitz, DT. "The ultrasound brain helmet for 3D transcranial Doppler imaging." Proceedings - IEEE Ultrasonics Symposium (2009).  Full Text
    • Ivancevich, NM, Pinton, GF, Nicoletto, HA, Bennett, E, Laskowitz, DT, and Smith, SW. "Real-time 3-D contrast-enhanced transcranial ultrasound and aberration correction." Ultrasound Med Biol 34, no. 9 (September 2008): 1387-1395.  Full Text  Link to Item
    • Ivancevich, NM, Pinton, GF, Smith, SW, Nicoletto, HA, Seism, M, Bennett, E, and Laskowitz, DT. "Real-time 3D contrast-enhanced transcranial ultrasound." Proceedings - IEEE Ultrasonics Symposium (2007): 550-553.  Full Text
    • Moretti, EW, Morris, RW, Podgoreanu, M, Schwinn, DA, Newman, MF, Bennett, E, Moulin, VG, Mba, UU, Laskowitz, DT, and Perioperative Genetics and Safety Outcomes Study (PEGASUS) Investigative Team, . "APOE polymorphism is associated with risk of severe sepsis in surgical patients." Crit Care Med 33, no. 11 (November 2005): 2521-2526.  Link to Item
    • Lynch, JR, Wang, H, Mace, B, Leinenweber, S, Warner, DS, Bennett, ER, Vitek, MP, McKenna, S, and Laskowitz, DT. "A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury." Exp Neurol 192, no. 1 (March 2005): 109-116.  Full Text  Link to Item
    • Lynch, JR, Tang, W, Wang, H, Vitek, MP, Bennett, ER, Sullivan, PM, Warner, DS, and Laskowitz, DT. "APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response." J Biol Chem 278, no. 49 (December 5, 2003): 48529-48533.  Full Text  Link to Item
    • Gong, JZ, Stenzel, TT, Bennett, ER, Lagoo, AS, Dunphy, CH, Moore, JO, Rizzieri, DA, Tepperberg, JH, Papenhausen, P, and Buckley, PJ. "Burkitt lymphoma arising in organ transplant recipients: a clinicopathologic study of five cases." Am J Surg Pathol 27, no. 6 (June 2003): 818-827.  Link to Item
    • Aono, M, Bennett, ER, Kim, KS, Lynch, JR, Myers, J, Pearlstein, RD, Warner, DS, and Laskowitz, DT. "Protective effect of apolipoprotein E-mimetic peptides on N-methyl-D-aspartate excitotoxicity in primary rat neuronal-glial cell cultures." Neuroscience 116, no. 2 (2003): 437-445.  Link to Item
    • Aono, M, Lee, Y, Grant, ER, Zivin, RA, Pearlstein, RD, Warner, DS, Bennett, ER, and Laskowitz, DT. "Apolipoprotein E protects against NMDA excitotoxicity." Neurobiol Dis 11, no. 1 (October 2002): 214-220.  Link to Item
    • Sato, Y, Laskowitz, DT, Bennett, ER, Newman, MF, Warner, DS, and Grocott, HP. "Differential cerebral gene expression during cardiopulmonary bypass in the rat: evidence for apoptosis?." Anesthesia and Analgesia 94, no. 6 (June 2002): 1389-1394.  Full Text
    • Laskowitz, DT, Thekdi, AD, Thekdi, SD, Han, SK, Myers, JK, Pizzo, SV, and Bennett, ER. "Downregulation of microglial activation by apolipoprotein E and apoE-mimetic peptides." Exp Neurol 167, no. 1 (January 2001): 74-85.  Full Text  Link to Item
    • Laskowitz, DT, Matthew, WD, Bennett, ER, Schmechel, D, Herbstreith, MH, Goel, S, and McMillian, MK. "Endogenous apolipoprotein E suppresses LPS-stimulated microglial nitric oxide production." Neuroreport 9, no. 4 (March 9, 1998): 615-618.  Link to Item
    • Laskowitz, DT, Goel, S, Bennett, ER, and Matthew, WD. "Apolipoprotein E suppresses glial cell secretion of TNF alpha." J Neuroimmunol 76, no. 1-2 (June 1997): 70-74.  Link to Item

  • Other Articles

    • Mackensen, GB, Ti, LK, Phillips-Bute, BG, Mathew, JP, Newman, MF, Grocott, HP, and Neurologic Outcome Research Group (NORG), . "Cerebral embolization during cardiac surgery: impact of aortic atheroma burden." Bja: British Journal of Anaesthesia 91, no. 5 (November 2003): 656-661.  Full Text
    • Swaminathan, M, McCreath, BJ, Phillips-Bute, BG, Newman, MF, Mathew, JP, Smith, PK, Blumenthal, JA, Stafford-Smith, M, and Perioperative Outcomes Research Group, . "Serum creatinine patterns in coronary bypass surgery patients with and without postoperative cognitive dysfunction." Anesth Analg 95, no. 1 (July 2002): 1-8.  Link to Item

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