Overview
Dr. Andrew Berchuck is Director of the Duke Division of Gynecologic Oncology and holds the James M. Ingram Distinguished Professorship. He is a practicing oncologist who is actively involved in the surgical and chemotherapy management of women with ovarian, endometrial and lower genital tract cancers. This includes minimally invasive laparoscopic surgical approaches. He also has developed a research program that focuses on the molecular-genetic alterations involved in malignant transformation of the ovarian and endometrial epithelium. He has published over 300 peer-reviewed papers in these areas. The objectives of his research include 1) identification of ovarian cancer susceptibility polymorphisms through a population-based case-control molecular epidemiologic study, and 2) use of genomic approaches to elucidate the molecular heterogenetity of ovarian cancer. Thirty fellows and residents have worked in his lab, several of whom are now funded investigators. His research efforts have been recognized nationally and he has received awards for best oral presentation at the annual meetings of both the Society of Gynecologic Oncology and the International Gynecologic Cancer Society. Dr. Berchuck was awarded the Barbara Thomason Ovarian Cancer Research Professorship by the American Cancer Society in 2006. He has served as editor of several books in the field including Principles and Practice of Gynecologic Oncology. Dr. Berchuck also has a major commitment to national activities, and was President of the Society of Gynecologic Oncology in 2008. He served as chair of the scientific advisory committee of the Ovarian Cancer Research Fund (http://www.ocrf.org) in New York City. Finally, he is also head of the steering committee of the international Ovarian Cancer Association Consortium (OCAC), a group of 50 case-control studies that are working together to identify ovarian cancer susceptibility polymorphisms (www.srl.cam.ac.uk/consortia/ocac/index.html).
Current Appointments & Affiliations
James M. Ingram Distinguished Professor of Gynecologic Oncology
·
2013 - Present
Obstetrics and Gynecology, Gynecologic Oncology,
Obstetrics and Gynecology
Professor of Obstetrics and Gynecology
·
1997 - Present
Obstetrics and Gynecology, Gynecologic Oncology,
Obstetrics and Gynecology
Chief of Gynecologic Oncology
·
2006 - Present
Obstetrics and Gynecology, Gynecologic Oncology,
Obstetrics and Gynecology
Member of the Duke Cancer Institute
·
1987 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Homologous Recombination Deficiency and Survival in Ovarian High-Grade Serous Carcinoma by Self-Reported Race.
Journal Article Cancer Epidemiol Biomarkers Prev · November 3, 2025 BACKGROUND: Half of ovarian high-grade serous carcinomas (HGSC) have homologous recombination deficiency (HRD). However, HRD is not well characterized in Black individuals who experience worse survival after a diagnosis of HGSC. The objective of this study ... Full text Link to item CiteAuthor Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.
Journal Article Nat Commun · September 8, 2025 Full text Link to item CiteHuman papillomavirus infection among patients with cervical cancer in Cambodia.
Journal Article BMC Womens Health · August 29, 2025 BACKGROUND: Cervical cancer is the second-most common cancer among Cambodian women, with an estimated 1274 new cases and 670 deaths annually. On October 5, 2023, the Cambodian government introduced HPV vaccination for 9-year-old girls into the country's na ... Full text Link to item CiteRecent Grants
Duke Women's Reproductive Health Research Scholars
Inst. Training Prgm or CMEAdvisor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2020 - 2030Experiences of Discrimination, Dysbiosis, and Racial Disparities in Ovarian Cancer
ResearchCo-Mentor · Awarded by National Cancer Institute · 2023 - 2028Elucidating racial and ethnic differences in functional effects of the vaginal microbiome in ovarian cancer
ResearchAdvisor · Awarded by National Cancer Institute · 2024 - 2027View All Grants
Education, Training & Certifications
Case Western Reserve University ·
1980
M.D.