Scholars@Duke
Michael Scott Berkoben

Michael Scott Berkoben

Professor of Medicine
Medicine, Nephrology
berko004@mc.duke.edu
Duke Box 2747, Durham, NC 27710
2424 Erwin Road - Suite 605, Durham, NC 27705

Selected Publications

The Treatment of Metabolic Acidosis: An Interactive Case-Based Learning Activity.

Journal Article MedEdPORTAL · September 27, 2019 INTRODUCTION: Metabolic acidosis is a dangerous and potentially life-threatening condition encountered in the inpatient and emergency department setting. Metabolic acidoses due to renal failure, bicarbonate losses, or lactic acidosis are common conditions, ... Full text Link to item Cite

Volume disorders and assessment

Chapter · January 1, 2019 Full text Cite

Digital chalk-talk videos improve knowledge and satisfaction in renal physiology.

Journal Article Adv Physiol Educ · March 1, 2018 The authors began a curriculum reform project to improve the experience in a Renal Physiology course for first-year medical students. Taking into account both the variety of learning preferences among students and the benefits of student autonomy, the auth ... Full text Open Access Link to item Cite

The effect of location and configuration on forearm and upper arm hemodialysis arteriovenous grafts.

Conference J Vasc Surg · November 2015 OBJECTIVE: The arteriovenous graft (AVG) is most often used in hemodialysis patients when an autogenous fistula is not feasible. The optimal location (forearm or upper arm) and configuration (loop or straight) of AVGs are not known. To evaluate relationshi ... Full text Link to item Cite

Cardiac diseases in maintenance hemodialysis patients: results of the HEMO Study.

Journal Article Kidney Int · June 2004 BACKGROUND: Cardiac disease is a common cause of death in chronic hemodialysis patients. A subanalysis of the data on cardiac diseases in the Hemodialysis (HEMO) Study was performed. The specific objectives were: (1) to analyze the prevalence of cardiac di ... Full text Link to item Cite

Infections in the dialysis patient

Chapter · January 1, 2003 Fever, chills, and rigors are the typical presenting symptoms of the hemodialysis patient who has graft-related bacteremia. Chills and rigors typically precede fever. These phenomena often occur during the hemodialysis treatment or shortly thereafter. Phys ... Cite

Patient mortality in chronic dialysis: comparisons between hemodialysis and peritoneal dialysis.

Journal Article Curr Opin Nephrol Hypertens · November 1999 Patients with approaching end-stage renal disease often must choose between hemodialysis or peritoneal dialysis as the initial form of renal replacement therapy. Should nephrologists recommend one form of dialysis as superior to the other? This review focu ... Full text Link to item Cite

Dialysis or transplantation: fitting the treatment to the patient.

Journal Article Annu Rev Med · 1999 Early referral of the patient with chronic renal failure will give the nephrologist time to fit the treatment to the patient. Planning for dialysis and transplantation should be undertaken concurrently. If the patient is not of advanced age and is not affl ... Full text Link to item Cite

A clustering of epidural abscesses in chronic hemodialysis patients: risks of salvaging access catheters in cases of infection.

Journal Article J Am Soc Nephrol · October 1996 The objective of this study was to investigate factors that might increase the risk of epidural abscesses in hemodialysis patients. The charts of all hemodialysis patients presenting with an epidural abscess over a period of 5 yr at Duke University Hospita ... Full text Link to item Cite

Medullary sponge kidney associated with congenital hemihypertrophy.

Journal Article J Am Soc Nephrol · August 1996 Medullary sponge kidney is a developmental disorder characterized by ectatic and cystic malformation of the collecting ducts and tubules. Clinical manifestations include urinary tract infections, renal stones, and hematuria. It can be associated with other ... Full text Link to item Cite

A hemodialysis patient with excruciating back pain

Journal Article Seminars in Dialysis · January 1, 1996 Full text Cite

Maintenance of permanent hemodialysis vascular access patency.

Journal Article ANNA J · February 1995 The morbidity and mortality of maintenance hemodialysis patients are in large part determined by the ability of the nephrologist, dialysis staff, and vascular surgeon to establish and maintain adequate vascular access. Primary arteriovenous fistulae are th ... Link to item Cite

Metabolism of 22-oxacalcitriol by a vitamin D-inducible pathway in cultured parathyroid cells.

Journal Article Biochem Biophys Res Commun · December 15, 1992 Catabolism of 22-oxacalcitriol (OCT) in parathyroid cells was compared to that of the parent hormone, 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]. Catabolism of both compounds was greatly accelerated by pretreatment of the cells with 1,25-(OH)2D3 or OCT. The r ... Full text Link to item Cite

Binding and metabolism of 1,25-dihydroxyvitamin D3 in cultured bovine parathyroid cells.

Journal Article Endocrinology · January 1992 Several laboratories, including ours, have reported that receptors for 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] are decreased in parathyroid glands of uremic animals and patients. To elucidate the factors involved in receptor regulation in this tissue, we h ... Full text Link to item Cite

Binding and metabolism of 1,25-dihydroxyvitamin D3 in cultured bovine parathyroid cells

Journal Article Endocrinology · 1992 Several laboratories, including ours, have reported that receptors for 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3] are decreased in parathyroid glands of uremic animals and patients. To elucidate the factors involved in receptor regulation in this tissue, we h ... Cite