Brenna L Hughes | Scholars@Duke

Brenna L Hughes
Associate Professor of Obstetrics and Gynecology

Current Appointments & Affiliations

Associate Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology 2018

Contact Information

Background
Education, Training, & Certifications
- M.D., Brown University 1999
Medical Licensure
- 2016-02015. North Carolina. 2019
Duke Appointment History
- Associate Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology 2017 - 2018
- Instructor, Temporary in the Department of Obstetrics and Gynecology, Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology 2016 - 2017
Leadership & Clinical Positions at Duke
- - Fellowship Director, Maternal-Fetal Medicine
Academic Positions Outside Duke
- Fellowship Director, Warren Alpert Medical School of Brown University. 2015 - 2016
- Director, Women and Infants Hospital. 2014 - 2016
- Associate Professor, Warren Alpert Medical School of Brown University. 2012 - 2016
- Assistant Professor, Warren Alpert Medical School of Brown University. 2006 - 2012
Recognition
Awards & Honors
Research
Selected Grants
- Population Health Research Support IDIQ Base awarded by National Institutes of Health 2018 - 2025
- Duke CTSA (KL2) awarded by National Institutes of Health 2018 - 2023
- Duke CTSA (TL1) awarded by National Institutes of Health 2018 - 2023
- Chronic Hypertension and Pregnancy (CHAP) NHLBI Multi-Site RCT awarded by University of Alabama at Birmingham 2014 - 2020
- Clinical and viral characteristics of maternal cytomegalovirus infection among seropositive pregnant women in the United States awarded by National Institutes of Health 2018 - 2020
- PTN_TO51_BMS01 awarded by Duke Clinical Research Institute 2018 - 2019
- Rapid, Near Patient Nucleic Acid Testing for Infant Cytomegalovirus (CMV) Infection awarded by Baebies, Inc 2017 - 2019
- MFMU Network Clinical Center Participation awarded by University of North Carolina - Chapel Hill 2016 - 2018
- VTEU 12-0021 Task C - Base awarded by National Institutes of Health 2016 - 2018
- VTEU 12-0021 - Task C Option 1 awarded by National Institutes of Health 2017 - 2018
- Effect of Latrogenic Delivery at 34-38 Weeks Gestation on Pregnancy Outcome awarded by Women & Infants Hospital 2016 - 2017
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Lantos, PM, Maradiaga-Panayotti, G, Barber, X, Raynor, E, Tucci, D, Hoffman, K, Permar, SR, Jackson, P, Hughes, BL, Kind, A, and Swamy, GK. "Geographic and Racial Disparities in Infant Hearing Loss." Otolaryngology Head and Neck Surgery : Official Journal of American Academy of Otolaryngology Head and Neck Surgery (October 9, 2018): 194599818803305-null. Full Text Open Access Copy
  - Hughes, BL. "Group A Streptococcus puerperal sepsis: an emerging obstetric infection?." Bjog : an International Journal of Obstetrics and Gynaecology (October 3, 2018). Full Text
  - Blackwell, SC, Gyamfi-Bannerman, C, Biggio, JR, Chauhan, SP, Hughes, BL, Louis, JM, Manuck, T, Miller, HS, Das, AF, Birch, R, and Jozwiakowski, MJ. "PROLONG Clinical Study Protocol: Hydroxyprogesterone Caproate to Reduce Recurrent Preterm Birth." American Journal of Perinatology 35, no. 12 (October 2018): 1228-1234. Full Text
  - Froehlich, RJ, Maggio, L, Has, P, Vrees, R, and Hughes, BL. "Improving Obstetric Hypertensive Emergency Treatment in a Tertiary Care Women's Emergency Department." Obstetrics and Gynecology 132, no. 4 (October 2018): 850-858. Full Text
  - Wood, AM, Dotters-Katz, SK, and Hughes, BL. "Cervical Cerclage versus Vaginal Progesterone for Management of Short Cervix in Low-Risk Women." American Journal of Perinatology (August 15, 2018). Full Text
  - Lantos, PM, Hoffman, K, Permar, SR, Jackson, P, Hughes, BL, Kind, A, and Swamy, G. "Neighborhood Disadvantage is Associated with High Cytomegalovirus Seroprevalence in Pregnancy." Journal of Racial and Ethnic Health Disparities 5, no. 4 (August 2018): 782-786. Full Text Open Access Copy
  - Datkhaeva, I, Has, P, Fitzgerald, K, and Hughes, BL. "Outcomes of a Negative Rapid Influenza Diagnostic Test in Pregnant Women." American Journal of Perinatology (July 9, 2018). Full Text
  - Sudhof, LS, Has, P, Rouse, DJ, and Hughes, BL. "Choice of Trial of Labor after Cesarean and Association with Likelihood of Success." American Journal of Perinatology 35, no. 9 (July 2018): 892-897. Full Text
  - Wood, AM, and Hughes, BL. "Detection and Prevention of Perinatal Infection: Cytomegalovirus and Zika Virus." Clinics in Perinatology 45, no. 2 (June 2018): 307-323. (Review) Full Text
  - Wood, AM, Livingston, EG, Hughes, BL, and Kuller, JA. "Intrahepatic Cholestasis of Pregnancy: A Review of Diagnosis and Management." Obstetrical & Gynecological Survey 73, no. 2 (February 2018): 103-109. (Review) Full Text
  - Society for Maternal-Fetal Medicine (SMFM). Electronic address: pubs@smfm.org, , Hughes, BL, Page, CM, and Kuller, JA. "Hepatitis C in pregnancy: screening, treatment, and management." American Journal of Obstetrics and Gynecology 217, no. 5 (November 2017): B2-B12. Full Text
  - Albright, CM, Has, P, Rouse, DJ, and Hughes, BL. "Internal Validation of the Sepsis in Obstetrics Score to Identify Risk of Morbidity From Sepsis in Pregnancy." Obstetrics and Gynecology 130, no. 4 (October 2017): 747-755. Full Text
  - Hughes, BL, Gans, KM, Raker, C, Hipolito, ER, and Rouse, DJ. "A Brief Prenatal Intervention of Behavioral Change to Reduce the Risk of Maternal Cytomegalovirus: A Randomized Controlled Trial." Obstetrics and Gynecology 130, no. 4 (October 2017): 726-734. Full Text
  - Lantos, PM, Hoffman, K, Permar, SR, Jackson, P, Hughes, BL, and Swamy, GK. "Geographic Disparities in Cytomegalovirus Infection During Pregnancy." Journal of the Pediatric Infectious Diseases Society 6, no. 3 (September 2017): e55-e61. Full Text
  - Albright, CM, Hughes, BL, and Werner, EF. "In Reply." Obstetrics and gynecology 130, no. 1 (July 2017): 217-218. Full Text
  - Albright, CM, Hughes, BL, and Werner, EF. "Group B Streptococci Screening Before Repeat Cesarean Delivery: A Cost-Effectiveness Analysis Reply." OBSTETRICS AND GYNECOLOGY 130, no. 1 (July 2017): 217-218. Full Text Link to Item
  - Grupper, M, Kuti, JL, Swank, ML, Maggio, L, Hughes, BL, and Nicolau, DP. "Population Pharmacokinetics of Cefazolin in Serum and Adipose Tissue From Overweight and Obese Women Undergoing Cesarean Delivery." Journal of Clinical Pharmacology 57, no. 6 (June 2017): 712-719. Full Text
  - Page, CM, Hughes, BL, Rhee, EHJ, and Kuller, JA. "Hepatitis C in Pregnancy: Review of Current Knowledge and Updated Recommendations for Management." Obstetrical & gynecological survey 72, no. 6 (June 2017): 347-355. (Review) Full Text
  - Datkhaeva, I, Dray, D, Has, P, Stifani, B, Hughes, BL, and Rouse, DJ. "Uptake of a Guideline for the Administration of a Rescue Course of Antenatal Corticosteroids." Obstetrics and Gynecology 129, no. 4 (April 2017): 720-726. Full Text
  - Hughes, BL, Clifton, RG, Hauth, JC, Leveno, KJ, Myatt, L, Reddy, UM, Varner, MW, Wapner, RJ, Mercer, BM, Peaceman, AM, Ramin, SM, Tolosa, JE, Saade, G, Sorokin, Y, and Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, . "Is Mid-trimester Insulin Resistance Predictive of Subsequent Puerperal Infection? A Secondary Analysis of Randomized Trial Data." American Journal of Perinatology 33, no. 10 (August 2016): 983-990. Full Text
  - Society for Maternal-Fetal Medicine (SMFM), , Hughes, BL, and Gyamfi-Bannerman, C. "Diagnosis and antenatal management of congenital cytomegalovirus infection." American Journal of Obstetrics and Gynecology 214, no. 6 (June 2016): B5-B11. (Review) Full Text
  - Hughes, BL. "Antibiotic prophylaxis in pregnancy-benefit without harm?." Bjog : an International Journal of Obstetrics and Gynaecology 123, no. 6 (May 2016): 994-null. Full Text
  - Albright, CM, Mehta, ND, Rouse, DJ, and Hughes, BL. "Sepsis in Pregnancy: Identification and Management." The Journal of Perinatal & Neonatal Nursing 30, no. 2 (April 2016): 95-105. Full Text
  - Briody, VA, Albright, CM, Has, P, and Hughes, BL. "Use of Cefazolin for Group B Streptococci Prophylaxis in Women Reporting a Penicillin Allergy Without Anaphylaxis." Obstetrics and Gynecology 127, no. 3 (March 2016): 577-583. Full Text
  - Ward, NS, Hughes, BL, and Mermel, LA. "Enterovirus D68 Infection in an Adult." American Journal of Critical Care : an Official Publication, American Association of Critical Care Nurses 25, no. 2 (March 2016): 178-180. Full Text
  - Hamel, MS, and Hughes, BL. "Zika infection in pregnancy: Pregnant women are worried, and their concern is warranted. here is what we know now and what’s being done about this health crisis." Contemporary Ob/Gyn 61, no. 8 (January 1, 2016). (Review)
  - Mainiero, AD, Rouse, DJ, Lopes, V, and Hughes, BL. "Association of 17α-Hydroxyprogesterone Caproate and Risk of Infection." Obstetrics and Gynecology 126, no. 1 (July 2015): 103-108. Full Text
  - Hamel, MS, Hughes, BL, and Rouse, DJ. "Whither oxygen for intrauterine resuscitation?." American Journal of Obstetrics and Gynecology 212, no. 4 (April 2015): 461-2. 461.e1-null. Full Text
  - Hamel, MS, Hughes, BL, and Rouse, DJ. "Reply: To PMID 24412117." American Journal of Obstetrics and Gynecology 212, no. 3 (March 2015): 410-null. (Letter) Full Text
- Book Sections
  - Hughes, BL. "Cytomegalovirus, Genital Herpes, Rubella, Syphilis, and Toxoplasmosis." In Protocols for High-Risk Pregnancies: An Evidence-Based Approach: Sixth Edition, 213-221. January 1, 2015. Full Text
- Conference Papers
  - Froehlich, RJ, Maggio, L, Has, P, Vrees, R, and Hughes, BL. "Improving the Treatment of Obstetric Hypertensive Emergency." 38th Annual Meeting and Pregnancy Meeting of the Society-for-Maternal-Fetal-Medicine. Dallas, TX. January 29, 2018 - February 3, 2018.: MOSBY-ELSEVIER, January 1, 2018. Link to Item
  - Hamel, M, Has, P, Datkhaeva, I, Delacy, K, Ciofli, D, and Hughes, BL. "The effect of intrapartum vancomycin on vaginal Group B streptococcus colony counts." December 2017. Full Text
  - Post, A, Raker, C, Gans, K, and Hughes, BL. "Patient perceptions of educational interventions for prevention of perinatal cytomegalovirus infection." December 2017. Link to Item
  - Reiff, ES, Grotegut, CA, Werner, EF, and Hughes, BL. "A cost analysis of adjunctive azithromycin prophylaxis for women undergoing non-elective cesarean delivery." December 2017. Link to Item
  - Wood, AM, Hughes, BL, Heine, RP, and Villers, MS. "Group B strep and associated complications in cesarean delivery." December 2017. Link to Item
  - Albright, CM, MacGregor, C, Sutton, D, Theva, M, Hughes, BL, and Werner, EF. "Group B Streptococci Screening Before Repeat Cesarean Delivery: A Cost-Effectiveness Analysis." January 2017. Full Text
  - Hughes, BL, Dutt, R, Raker, C, Barthelemy, M, Rossoll, RM, Ramratnam, B, Wira, CR, and Cu-Uvin, S. "The impact of pregnancy on anti-HIV activity of cervicovaginal secretions." December 2016. Full Text
  - Albright, CM, Emerson, JB, Werner, EF, and Hughes, BL. "Third-Trimester Prenatal Syphilis Screening: A Cost-Effectiveness Analysis." September 2015. Full Text
  - Maggio, L, Nicolau, DP, DaCosta, M, Rouse, DJ, and Hughes, BL. "Cefazolin prophylaxis in obese women undergoing cesarean delivery: a randomized controlled trial." May 2015. Full Text
Scholarly, Clinical, & Service Activities
Presentations & Appearances

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.

Education, Training, & Certifications

Medical Licensure

Duke Appointment History

Leadership & Clinical Positions at Duke

Academic Positions Outside Duke

Awards & Honors

Selected Grants

Selected Publications

Academic Articles

Book Sections

Conference Papers

Presentations & Appearances