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Brenna L Hughes

Edwin Crowell Hamblen Distinguished Professor of Reproductive Biology and Family Planning
Obstetrics and Gynecology, Maternal Fetal Medicine

Current Duke Appointments & Affiliations


Edwin Crowell Hamblen Distinguished Professor of Reproductive Biology and Family Planning · 2025 - Present Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology
Professor of Obstetrics and Gynecology · 2023 - Present Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology
Interim Chair, Department of Obstetrics and Gynecology · 2025 - Present Obstetrics and Gynecology, Clinical Science Departments

Recent News Items


Published March 25, 2025
Duke Honors 31 New Distinguished Professors
Published August 23, 2023
A Multifaceted Effort to Reduce Maternal Mortality
Published February 17, 2023
Further Restricting Abortions in NC Will Have ‘Chilling’ Effect, Doctors Say

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Recent Scholarly Works


The Impact of a Protocol on Equitable Labor and Delivery Substance Use Screening: A Retrospective Cohort Study.

Journal article Am J Perinatol · July 2026 OBJECTIVE: The Society for Maternal-Fetal Medicine (SMFM), the American College of Obstetricians and Gynecologists (ACOG), and the American Society of Addiction Medicine (ASAM) jointly recommend universal substance use screening in pregnancy with a validat ... Full text Link to item Cite

Neonatal Inflammatory Profiles Associated With Perinatally Acquired Hepatitis C Viral Infection.

Journal article Pediatr Infect Dis J · May 5, 2026 In this nested case-control study of infants with in utero hepatitis C exposure, we assessed 21 plasma cytokines/chemokines at age 2 months in 11 infants with perinatal transmission and 11 negative controls. Of 6 detectable biomarkers, cases exhibited high ... Full text Link to item Cite

The association between postpartum aspirin use and NT-proBNP levels as a marker for maternal cardiac health: a randomized controlled trial.

Journal article Am J Obstet Gynecol · May 2026 BACKGROUND: During pregnancy, administration of low-dose aspirin 81 mg (LDA) has been demonstrated to decrease the incidence of preeclampsia in at-risk individuals. However, the role of continuation of LDA in the postpartum period and its association with ... Full text Link to item Cite
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Recent Grants


Duke Women's Reproductive Health Research Scholars

Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2020 - 2030

Duke MFMU Capitation Record (GOALPOST)

Clinical TrialPrincipal Investigator · Awarded by The George Washington University · 2025 - 2030

Duke MFMU Capitation Record

Clinical TrialPrincipal Investigator · Awarded by The George Washington University · 2023 - 2030

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Education


Brown University · 1999 M.D.

External Links


Duke Health Profile