Scholars@Duke
Brenna L Hughes

Brenna L Hughes

Edwin Crowell Hamblen Distinguished Professor of Reproductive Biology and Family Planning
Obstetrics and Gynecology, Maternal Fetal Medicine

Current Appointments & Affiliations

Edwin Crowell Hamblen Distinguished Professor of Reproductive Biology and Family Planning · 2025 - Present Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology
Professor of Obstetrics and Gynecology · 2023 - Present Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology
Interim Chair, Department of Obstetrics and Gynecology · 2025 - Present Obstetrics and Gynecology, Clinical Science Departments

In the News

Published March 25, 2025
Duke Honors 31 New Distinguished Professors
Published August 23, 2023
A Multifaceted Effort to Reduce Maternal Mortality
Published February 17, 2023
Further Restricting Abortions in NC Will Have ‘Chilling’ Effect, Doctors Say

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Recent Publications

Outcomes of extremely preterm infants exposed to prolonged prelabor rupture of membranes before 24 weeks of gestation.

Journal Article Am J Obstet Gynecol · August 2025 BACKGROUND: Preterm prelabor rupture of membranes before or around the limit of fetal viability is associated with serious maternal and neonatal complications, including chorioamnionitis, extremely preterm birth, and pulmonary hypoplasia. OBJECTIVE: This s ... Full text Link to item Cite

The association of cytomegalovirus hyperimmune globulin with adverse pregnancy outcomes.

Journal Article Am J Obstet Gynecol · August 2025 OBJECTIVE:: Because a prior randomized trial suggested that cytomegalovirus (CMV) hyperimmune globulin (HIG) might increase the frequency of adverse pregnancy outcomes, we assessed whether there was such an association in our more recent and larger trial. ... Full text Link to item Cite
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Recent Grants

Duke Women's Reproductive Health Research Scholars

Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2020 - 2030

Duke MFMU Capitation Record (GOALPOST)

Clinical TrialPrincipal Investigator · Awarded by The George Washington University · 2025 - 2030

Duke University Maternal-Fetal Medicine Units (MFMU) Network Clinical Center

ResearchPrincipal Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2023 - 2030

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Education, Training & Certifications

Brown University · 1999 M.D.

External Links

Duke Health Profile