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Brenna L Hughes

Edwin Crowell Hamblen Distinguished Professor of Reproductive Biology and Family Planning
Obstetrics and Gynecology, Maternal Fetal Medicine

Current Appointments & Affiliations


Edwin Crowell Hamblen Distinguished Professor of Reproductive Biology and Family Planning · 2025 - Present Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology
Professor of Obstetrics and Gynecology · 2023 - Present Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology
Interim Chair, Department of Obstetrics and Gynecology · 2025 - Present Obstetrics and Gynecology, Clinical Science Departments

In the News


Published March 25, 2025
Duke Honors 31 New Distinguished Professors
Published August 23, 2023
A Multifaceted Effort to Reduce Maternal Mortality
Published February 17, 2023
Further Restricting Abortions in NC Will Have ‘Chilling’ Effect, Doctors Say

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Recent Publications


Long COVID After Acquisition of the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) During Pregnancy Compared With Outside of Pregnancy.

Journal Article Obstet Gynecol · March 1, 2026 OBJECTIVE: To evaluate whether the risk of long COVID among individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) during pregnancy differs from that of individuals who were not pregnant at time of virus acquisition. METHODS ... Full text Link to item Cite

Early Postnatal Polymerase Chain Reaction Testing in the Identification of Perinatal Transmission of Hepatitis C Virus.

Journal Article Clin Infect Dis · February 4, 2026 In this study, a single hepatitis C virus (HCV) RNA at 2-6 months was sensitive and specific (86.7% and 95% confidence interval [CI], 62.1%-96.3% and 100% and 95% CI, 98.8%-100%, respectively) in identifying perinatal transmission of HCV. No cases of perin ... Full text Link to item Cite

Intrauterine SARS-CoV-2 Exposure and Infant Neurodevelopment through 18 Months of Age: Findings from the Researching COVID to Enhance Recovery (RECOVER) Pregnancy Study.

Journal Article J Pediatr · January 19, 2026 OBJECTIVE: To assess associations between exposure to intrauterine SARS-CoV-2 and subsequent child neurodevelopment in a large, diverse cohort with confirmation of maternal SARS-CoV-2 status. STUDY DESIGN: The Researching COVID to Enhance Recovery (RECOVER ... Full text Link to item Cite
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Recent Grants


Duke Women's Reproductive Health Research Scholars

Inst. Training Prgm or CMEMentor · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2020 - 2030

Duke MFMU Capitation Record (GOALPOST)

Clinical TrialPrincipal Investigator · Awarded by The George Washington University · 2025 - 2030

Duke University Maternal-Fetal Medicine Units (MFMU) Network Clinical Center

ResearchPrincipal Investigator · Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development · 2023 - 2030

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Education


Brown University · 1999 M.D.

External Links


Duke Health Profile