Overview
Dr. Birgit Frauscher is a clinician scientist whose career is dedicated to improve diagnosis and prognosis of people with epilepsy by developing new methods based on advanced electroencephalography techniques to better localize the epileptic focus in order to improve epilepsy treatment outcomes and ultimately achieve the best possible quality of life. She is currently holding the position of Director of the Duke Comprehensive Epilepsy Center and holds a secondary appointment with the Department of Biomedical Engineering at the Duke Pratt School of Engineering.
Her academic journey started at the Medical University of Innsbruck in Austria, where she accomplished her medical training, residency in neurology, and subspecialty training in electroencephalography, epilepsy and sleep medicine. Early in her career during Medical School she became fascinated by the technique of electroencephalography and how it allows to draw important conclusions on brain function. After completion of her clinical training in 2008, she underwent subsequent research training resulting in the successful completion of her habilitation degree in 2011. To specialize on intracranial EEG and signal analysis, she spent a visiting professorship at the Montreal Neurological Institute and Hospital, McGill University in Canada between 2013 – 2015. Subsequently, she served at the Montreal Neurological Institute and Hospital as an Attending Epileptologist and later as Group Leader of Epilepsy and Professor of Neurology.
Her research interests include i) the development of novel seizure-independent EEG markers for the epileptogenic zone in order to achieve a more accurate diagnosis of epilepsy, ii) the investigation of the important interactions between sleep and epilepsy, and iii) the use of the unique possibility of invasive intracranial EEG for studying brain physiology during wakefulness and sleep in order to better delineate normal from abnormal intracranial EEG activity.
Dr. Frauscher’s publication record holds over 170 peer-reviewed papers dedicated to epilepsy and sleep with a H-index of 62. Her scholarly endeavors have earned her several prestigious awards, including Clinician-Scientist awards of the FRSQ (2018-2023), the Michael Prize of the International League against Epilepsy (2019) and the Ernst Niedermeyer Prize from the Austrian Epilepsy Society (2015). Dr. Frauscher's dedication to pushing the boundaries of epilepsy and sleep research highlights her standing in the field and her significant contributions to advancing clinical knowledge.
Current Appointments & Affiliations
Recent Publications
Inroads into epilepsy through high-frequency oscillations: Achievements and benchmark areas for improvement.
Journal Article Epilepsia · January 28, 2026 High-frequency oscillations (HFOs) were discovered more than 20 years ago, and since then they have been studied intensively in the context of epilepsy. HFOs encompass a broad spectrum of oscillations, typically ranging from 80 Hz to several kHz, that incl ... Full text Link to item CiteFast Ripples Measured From Overnight SEEG Recordings as Markers of the Epileptogenic Zone: A Multicenter Validation Study.
Journal Article Neurology · January 27, 2026 BACKGROUND AND OBJECTIVES: Epilepsy surgery outcomes after intracranial EEG remain suboptimal necessitating the discovery of additional biomarkers to define the epileptogenic zone. Fast ripples (FRs) are a promising, new interictal epilepsy biomarker. By a ... Full text Link to item CiteRhythms and Background (RnB): The Spectroscopy of Sleep Recordings.
Journal Article eNeuro · January 13, 2026 Non-rapid eye movement (NREM) sleep is characterized by the interaction of multiple oscillations essential for memory consolidation, alongside a dynamic arrhythmic 1/f scale-free background that may also contribute to its functions. Recent spectral paramet ... Full text Link to item CiteRecent Grants
The overlap of speech production and verbal working memory
ResearchCo Investigator · Awarded by National Institute of Neurological Disorders and Stroke · 2023 - 2028Influence of thalamic sleep spindles on epileptic activity
ResearchPrincipal Investigator · Awarded by American Academy of Sleep Medicine Foundation · 2025 - 2026Neurostimulation and Recording of Real World Spatial Navigation in Humans
ResearchInvestigator · Awarded by National Institutes of Health · 2025 - 2026View All Grants