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Barbara D Lipes

Assistant Professor in Medicine
Medicine, Cardiology
Box 102143 Med Ctr, Durham, NC 27710
198A CARL Building, Durham, NC 27710

Current Duke Appointments & Affiliations


Assistant Professor in Medicine · 2021 - Present Medicine, Cardiology, Medicine

Recent Scholarly Works


Abstract 5191: Multiscale engineering of PTPRZ1 CAR T cells through affinity-tuned binders and modular architecture optimization

Conference Cancer Research · April 3, 2026 AbstractGlioblastoma remains universally lethal, with rapid recurrence and a median survival of less than two years. Current CAR T approaches in glioblastoma have been limited by a lack of uniformly expre ... Full text Cite

EXTH-68. Targeting Tumor Heterogeneity And Plasticity in Glioblastoma With Novel CAR T Cells Targeting PTPRZ1

Conference Neuro-Oncology · November 11, 2025 AbstractGlioblastoma (GBM) remains among the most aggressive and intractable human cancers, driven by profound intratumoral heterogeneity, dynamic cellular plasticity, and robust mechanisms of immune esca ... Full text Cite
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Recent Grants


Development of Diagnostic Antibodies for Acute and Chronic Chagas Disease

ResearchCo Investigator · Awarded by National Institutes of Health · 2025 - 2028

Harnessing B Cells after Stem Cell Transplant to Produce Novel CAR-Ts

ResearchResearch Associate · Awarded by National Institutes of Health · 2025 - 2027

Development of point-of-care testing for Lassa and other hemorrhagic fever arenaviruses

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

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Education


University of North Carolina, Chapel Hill · 1995 Ph.D.