Cecil Orm Borel III

My long term career interests center around anesthesia and critical care for patients with life-threatening neurological illnesses. I am particularly interested in respiratory dysfunction as the result of neurocritical illness. Recently I have been involved with projects to explore the pathophysiology of cerebral vasospasm following subarachnoid hemorrhage in vivo and in vitro models, the role of magnesium in cerebral vasospasm, and technical aspects of neuroanesthesia related to awake craniotomy and endovascular cerebrovascular surgery.

Current Appointments & Affiliations

Professor Emeritus · 2012 - Present Anesthesiology, Neuroanesthesia, Anesthesiology

Chief, Division of Neuroanesthesia · 2006 - Present Anesthesiology, Neuroanesthesia, Anesthesiology

Recent Publications

A novel application for bolus remifentanil: blunting the hemodynamic response to Mayfield skull clamp placement.

Journal Article Curr Med Res Opin · February 2014 OBJECTIVE: Neurosurgery often requires skull immobilization with a Mayfield clamp, which often causes brief intense nociceptive stimulation, hypertension and tachycardia. Blunting this response may help prevent increased intracranial pressure, cerebral ane ... Full text Link to item Cite

Neuroprotective effect of curcumin in an experimental rat model of subarachnoid hemorrhage.

Journal Article Anesthesiology · December 2011 BACKGROUND: Subarachnoid hemorrhage (SAH) causes a high mortality rate and morbidity. It was suggested that oxidant stress plays an important role in neuronal injury after SAH. Therefore, we assessed the effect of curcumin on reducing cerebral vasospasm an ... Full text Link to item Cite

A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy.

Journal Article Anesth Analg · April 2011 BACKGROUND: Postoperative nausea and vomiting (PONV) occur commonly after craniotomy. In patients receiving prophylaxis with ondansetron and dexamethasone, vomiting occurred in 45% of patients at 48 hours. In addition to causing patient discomfort, the phy ... Full text Link to item Cite

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Education, Training & Certifications

Drexel University · 1977 M.D.