Caitlin Paisley

Journal Article Dev Biol · October 2021 Throughout the central nervous system, astrocytes adopt precisely ordered spatial arrangements of their somata and arbors, which facilitate their many important functions. Astrocyte pattern formation is particularly important in the retina, where astrocyte ... Full text Link to item Cite

Endogenous opioid peptides and brain development: Endomorphin‐1 and Nociceptin play a sex‐specific role in the control of oligodendrocyte maturation and brain myelination

Journal Article Glia · July 2020 AbstractThe generation of fully functional oligodendrocytes, the myelinating cells of the central nervous system, is preceded by a complex maturational process. We previously showed that the timing of ... Full text Cite

Large-scale death of retinal astrocytes during normal development is non-apoptotic and implemented by microglia.

Journal Article PLoS Biol · October 2019 Naturally occurring cell death is a fundamental developmental mechanism for regulating cell numbers and sculpting developing organs. This is particularly true in the nervous system, where large numbers of neurons and oligodendrocytes are eliminated via apo ... Full text Link to item Cite

Novel role of the nociceptin system as a regulator of glutamate transporter expression in developing astrocytes.

Journal Article Glia · December 2017 Our previous results showed that oligodendrocyte development is regulated by both nociceptin and its G-protein coupled receptor, the nociceptin/orphanin FQ receptor (NOR). The present in vitro and in vivo findings show that nociceptin plays a crucial conse ... Full text Cite