Current Appointments & Affiliations
Professor of Medicine
·
2020 - Present
Medicine, Medical Oncology,
Medicine
Chief, Division of Medical Oncology
·
2021 - Present
Medicine, Medical Oncology,
Medicine
Member of the Duke Cancer Institute
·
2019 - Present
Duke Cancer Institute,
Institutes and Centers
Recent Publications
Triple Negative Breast Cancer and Brain Metastases.
Journal Article Clin Breast Cancer · December 2023 The treatment of metastatic breast cancer (MBC) has improved over the past decade, however prognosis continues to be mitigated by the fact that about 1 in 5 patients with MBC will develop brain metastases (BrM) during their metastatic disease course. 1 Thi ... Full text Link to item CiteSystemic Therapy Approaches for Breast Cancer Brain and Leptomeningeal Metastases.
Journal Article Curr Treat Options Oncol · October 2022 Brain metastasis arising from breast cancer is associated with a poor prognosis. Various systemic chemotherapy and targeted therapies which are effective against breast cancer often fail to provide benefits against brain metastasis. This is mainly due to l ... Full text Link to item CiteExamination and prognostic implications of the unique microenvironment of breast cancer brain metastases.
Journal Article Breast Cancer Res Treat · July 2019 PURPOSE: Brain metastases (BM) are a complication of advanced breast cancer (BC). Histology of melanoma BM offers prognostic value; however, understanding the microenvironment of breast cancer brain metastases (BCBM) is less characterized. This study repor ... Full text Link to item CiteRecent Grants
DATO-BASE: A phase 2 trial of DATOpotamab-deruxtecan for breast cancer Brain metAstaSEs
Clinical TrialPrincipal Investigator · Awarded by Dana-Farber Cancer Institute · 2024 - 2029BGB-43395-101 (CDK-4) - A Phase 1a/1b Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of the CDK4 Inhibitor BGB-43395
Clinical TrialPrincipal Investigator · Awarded by BeiGene USA, Inc. · 2024 - 2029A single shot therapy will accelerate the elimination of breast cancer
ResearchCo Investigator · Awarded by United States Army Medical Research Acquisition Activity · 2024 - 2028View All Grants
Education, Training & Certifications
East Carolina University, Brody School of Medicine ·
2002
M.D.