Journal ArticleInt J Clin Oncol · October 2025
PURPOSE: To describe real-world characteristics and clinical outcomes among patients with HER2+ MBC receiving tucatinib-based treatments. METHODS: This retrospective study included patients diagnosed with HER2+ MBC between January 2017 and December 2022 fr ...
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Journal ArticleActa neuropathologica communications · May 2025
BackgroundBrain metastases (BrM) arising from breast cancer (BC) are an increasing consequence of advanced disease, with up to half of patients with metastatic HER2 + or triple negative BC experiencing central nervous system (CNS) recurrence. The ...
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Journal ArticleClin Breast Cancer · December 2023
The treatment of metastatic breast cancer (MBC) has improved over the past decade, however prognosis continues to be mitigated by the fact that about 1 in 5 patients with MBC will develop brain metastases (BrM) during their metastatic disease course. 1 Thi ...
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Journal ArticleCurr Treat Options Oncol · October 2022
Brain metastasis arising from breast cancer is associated with a poor prognosis. Various systemic chemotherapy and targeted therapies which are effective against breast cancer often fail to provide benefits against brain metastasis. This is mainly due to l ...
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Journal ArticleBreast Cancer Res Treat · July 2019
PURPOSE: Brain metastases (BM) are a complication of advanced breast cancer (BC). Histology of melanoma BM offers prognostic value; however, understanding the microenvironment of breast cancer brain metastases (BCBM) is less characterized. This study repor ...
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