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Carlos Perez Arques CV

Postdoctoral Associate
Molecular Genetics and Microbiology
Office hours 9:00 AM - 6:00 PM  
CV

Overview


I am a postdoctoral associate working in the Heitman lab as part of the Department of Molecular Genetics and Microbiology of the School of Medicine. I graduated as a Ph. D. in Molecular Biology and Biotechnology from the University of Murcia in Spain, my home country and a wonderful place to visit. I am fascinated by fungal biology and especially, in molecular mechanisms exploited by opportunistic pathogens to cause disease.

In my spare time, I love building themed LEGO sets, the bigger the better, from my favorite movie sagas. I am a big science fiction and fantasy fan, but I also like classic films -particularly film noir and western- and old jidaigeki and chanbara movies. Also, I like to play games, either video or board games, and going out once in a while. Especially, if there is food involved.

Current Appointments & Affiliations


Recent Publications


Heterochromatin and RNAi act independently to ensure genome stability in Mucorales human fungal pathogens.

Journal Article Proc Natl Acad Sci U S A · February 14, 2023 Chromatin modifications play a fundamental role in controlling transcription and genome stability and yet despite their importance, are poorly understood in early-diverging fungi. We present a comprehensive study of histone lysine and DNA methyltransferase ... Full text Link to item Cite

Transformation and CRISPR-Cas9-mediated homologous recombination in the fungus Rhizopus microsporus.

Journal Article STAR protocols · March 2022 Here, we describe a reliable approach for targeted DNA integrations in the genome of R. microsporus, one of the main causal agents of mucormycosis. We provide a strategy for stable, targeted integration of DNA templates by homologous recombination ( ... Full text Cite

Stable and reproducible homologous recombination enables CRISPR-based engineering in the fungus Rhizopus microsporus.

Journal Article Cell reports methods · December 2021 Mucormycosis is a lethal and emerging disease that has lacked a genetic model fulfilling both high virulence and the possibility of performing stable and reproducible gene manipulation by homologous recombination (HR). Here, we developed a new methodology ... Full text Cite
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Recent Grants


RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis

ResearchPostdoctoral Associate · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

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