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Carol Anne Colton
Professor in Neurology
Neurology, Behavioral Neurology
carol.colton@duke.edu
Duke Box 2900, Durham, NC 27710
201H Bryan Res Bldg, Durham, NC 27710
Research
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At a Glance
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Credentials
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Academic Experience
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Expertise
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Research
Selected Grants
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Publications
Selected Publications
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Teaching
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Advising & Mentoring
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Recognition
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Selected Grants
Hypoperfusion, Hemodynamic Control Domains and Neurovascular Dysregulation in AD brain pathology
Research
Co Investigator ·
Awarded by National Institute on Aging ·
2023 - 2027
Cardiac photon counting CT and its application in studying interactions between Alzheimer's and heart disease
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2021 - 2027
Extracranial Brain Stimulation Reduces Metabolic Insufficiency Through Enhanced Cerebral Blood Flow in CVN-AD Alzheimer's Model
Research
Investigator ·
Awarded by National Institute on Aging ·
2022 - 2026
Duke Creating ADRD Researchers for the Next Generation - Stimulating Access to Research in Residency Program (CARiNG-StARR)"
Inst. Training Prgm or CME
Preceptor ·
Awarded by National Institutes of Health ·
2020 - 2025
Brain networks in mouse models of aging
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2019 - 2025
Gender and APOE genotype interact to alter immune regulated metabolism in AD
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2019 - 2024
Role of Rab10 in Alzheimer's disease
Research
Advisor ·
Awarded by National Institutes of Health ·
2022 - 2023
Bioelectronic regulation of CNS lymphatic drainage in delirium and AD.
Research
Co Investigator ·
Awarded by Alzheimer's Association ·
2019 - 2023
Interactions between the immune system, genetics and environmental mitochondrial toxicants in models of Parkinson's disease
Research
Co-Mentor ·
Awarded by Department of Defense ·
2020 - 2022
The Effect of Exercise Type, Dose, and Intensity on Plasma Amyloid Beta and Tau in Healthy Adults
Research
Mentor ·
Awarded by Dementia Alliance of North Carolina ·
2019 - 2021
Novel Orally Available Prodrugs for Alzheimer's Disease
Research
Principal Investigator ·
Awarded by RESILIO THERAPEUTICS, LLC ·
2017 - 2020
Immune-based nutrient deprivation and neurodegenerative disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2013 - 2020
Onset of immune pathlogy in AD
Research
Principal Investigator ·
Awarded by Alzheimer's Association ·
2016 - 2019
Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer
Equipment
Major User ·
Awarded by National Institutes of Health ·
2018 - 2019
Gender and APOE genotype interact to alter immune regulated metabolism in AD
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2017 - 2019
Hippocampal Neurovascular Plasticity in CVN-AD Mouse: Fornix-Septal Stimulation
Research
Collaborating Investigator ·
Awarded by National Institutes of Health ·
2016 - 2019
Quantitative MR Microscopy of Phenotypic Biomarkers in Alzheimer's Disease
Research
Co-Mentor ·
Awarded by National Institutes of Health ·
2013 - 2018
Immune regulated amino acid pathways in Alzheimer's Disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2016 - 2018
Immunosuppression in humans with AD
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2016 - 2018
UNIVERSITY HOSPITALS HARRINGTON DISCOVERY INSTITUTE ADDF HARRINGTON SCHOLAR GRANT AGREEMENT
Research
Principal Investigator ·
Awarded by UH Harrington Discovery Institute ·
2015 - 2017
Slowing arginine utilization by inhibiting arginase and ornithine decarboxylase with DFMO
Research
Principal Investigator ·
Awarded by Alzheimer's Drug Discovery Foundation ·
2014 - 2016
Instrumentation for Quantitative Phosphoproteomics and Acetylomics
Equipment
Major User ·
Awarded by National Institutes of Health ·
2014 - 2015
A Mouse Model of Inflammation in Alzheimer's Disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2009 - 2014
The amyloid cascade in a novel mouse model of Alzheimer's disease
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2009 - 2014
Creating a mouse model for neurodegenerative disease by "humanizing" NOS2
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2009 - 2012
Increasing sensitivity to enviromental stress by humanizing NOS2 in mouse
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2009 - 2012
Dysregulation of the neurovascular unit in Alzheimer's Disease
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2007 - 2010
Immune Responsiveness, APOE/Gender in Neurodegeneration
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2004 - 2009
Regulation of neuronal NO by apolipoprotein E
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2002 - 2007
Regulation of microglial activation
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2001 - 2005
Regulation of microglial function by ApoE
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
1998 - 2003
