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Cassio Mendes Fontes

Assistant Research Professor in the Department of Biomedical Engineering
Biomedical Engineering

Current Appointments & Affiliations


Assistant Research Professor in the Department of Biomedical Engineering · 2023 - Present Biomedical Engineering, Pratt School of Engineering

Recent Publications


Synthetic biomolecular condensates enhance translation from a target mRNA in living cells.

Journal Article Nat Chem · March 2025 Biomolecular condensates composed of proteins and RNA are one approach by which cells regulate post-transcriptional gene expression. Their formation typically involves the phase separation of intrinsically disordered proteins with a target mRNA, sequesteri ... Full text Link to item Cite

Environmentally Resilient Microfluidic Point-of-Care Immunoassay Enables Rapid Diagnosis of Talaromycosis.

Journal Article ACS Sens · June 23, 2023 Point-of-care tests (POCTs) are increasingly being used in field settings, particularly outdoors. The performance of current POCTs─most commonly the lateral flow immunoassay─can be adversely affected by ambient temperature and humidity. We developed a self ... Full text Link to item Cite

COVID-19 Diagnosis and SARS-CoV-2 Strain Identification by a Rapid, Multiplexed, Point-of-Care Antibody Microarray.

Journal Article Anal Chem · April 4, 2023 Antigen tests to detect SARS-CoV-2 have emerged as a promising rapid diagnostic method for COVID-19, but they are unable to differentiate between variants of concern (VOCs). Here, we report a rapid point-of-care test (POC-T), termed CoVariant-SPOT, that us ... Full text Open Access Link to item Cite
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Recent Grants


Development of point-of-care testing for Lassa and other hemorrhagic fever arenaviruses

ResearchResearch Scientist · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

A Fully Integrated Point-of-Care Test for Ebola

ResearchResearch Scientist · Awarded by National Institutes of Health · 2020 - 2025

Generation of antibodies specific for optimal non-HRP2 malaria diagnostic antigens

ResearchGraduate Student · Awarded by National Institutes of Health · 2020 - 2023

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Education, Training & Certifications


Duke University · 2020 Ph.D.