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Christopher Dale Kontos

Professor of Medicine
Medicine, Cardiology
Duke Box 102148, Durham, NC 27710
180A CARL Bldg, 213 Research Dr., Durham, NC 27710

Selected Grants


Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2028

Staphylococcus aureus Cardiac Device Infections - From the Vascular Viewpoint (K23)

ResearchMentor · Awarded by National Institutes of Health · 2022 - 2027

Medical Scientist Training Program

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2022 - 2027

Genetic Dissection of Angiogenesis in the Tuberculous Granuloma

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Stimulating Access to Research in Residency (StARR) - NHLBI

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2018 - 2028

Staphylococcus aureus Cardiac Device Infections - From the Vascular Viewpoint (K23)

ResearchMentor · Awarded by National Institutes of Health · 2022 - 2027

Medical Scientist Training Program

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2022 - 2027

Genetic Dissection of Angiogenesis in the Tuberculous Granuloma

ResearchCo Investigator · Awarded by National Institute of Allergy and Infectious Diseases · 2022 - 2027

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Integrated Training in Anesthesiology Research

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1996 - 2026

Mechanisms Regulating Vascular Homeostasis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2025

Duke CTSA (TL1) Year 5

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024

Macrophage-Satellite Cell Interactions in the Ischemic Limb

ResearchMentor · Awarded by Vascular Cures · 2021 - 2024

Gertrude B. Elion Mentored Medical Student Award

FellowshipPrincipal Investigator · Awarded by Triangle Community Foundation · 2023 - 2024

Investigating the Metabolic Reprogramming of Ovarian Tumors During Omental Metastasis

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2021 - 2024

Variant Determinants of African American Limb Pathology in Peripheral Arterial Disease

ResearchPrincipal Investigator · Awarded by East Carolina University · 2021 - 2024

Printed Electronic Biosensors for Point-of-Care Testing of Cardiovascular Biomarkers

ResearchCo Investigator · Awarded by National Institutes of Health · 2019 - 2024

The Anti-angiogenic VEGF165b and VEGFR1 Signaling in Peripheral Artery Disease

ResearchPrincipal Investigator · Awarded by Augusta University · 2019 - 2023

Duke Training Grant in Nephrology

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1995 - 2023

Multidisciplinary Heart and Vascular Diseases

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2023

Gertrude B. Elion Mentored Medical Student Award

FellowshipPrincipal Investigator · Awarded by Triangle Community Foundation · 2021 - 2023

Gertrude B. Elion Mentored Medical Student Award

FellowshipPrincipal Investigator · Awarded by Triangle Community Foundation · 2021 - 2022

U01 RPPR: Mitigators of Radiation-Induced Endovascular Injury: Targeting Tie2 and Thrombocytopenia

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2017 - 2022

Medical Scientist Training Program

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 2022

Gertrude B. Elion Mentored Medical Student Award

FellowshipPrincipal Investigator · Awarded by Triangle Community Foundation · 2019 - 2021

TIE2 Activation for the Treatment of Chemical-Induced Acute Lung Injury

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2020

Organization and Function of Cellular Structure

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 1975 - 2020

Pharmacology Industry Internships for Ph.D. Students

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by American Society for Pharmacology and Experimental Therapeutics · 2017 - 2019

Support for A Physician-Scientist Training Summit for MD-PhD and Post-Graduate Physician-Scientist Training Program Directors

ConferencePrincipal Investigator · Awarded by Burroughs Wellcome Fund · 2019 - 2019

The Anti-angiogenic VEGF165b and VEGFR1 Signaling in Peripheral Artery Disease

ResearchPrincipal Investigator · Awarded by University of Virginia - Charlottesville · 2018 - 2019

A Novel Molecular Regulator of Vascular Homeostasis

ResearchPrincipal Investigator · Awarded by American Heart Association · 2016 - 2019

The role of muscle progenitor cells in muscle and vascular regeneration in PAD

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2017 - 2019

Gertrude Elion Mentored Medical Research Award

FellowshipPrincipal Investigator · Awarded by Triangle Community Foundation · 2018 - 2019

Macrophages and Treatment-Resistant NVAMD

ResearchAdvisor · Awarded by National Institutes of Health · 2015 - 2019

Skeletal Muscle and Vascular Remodeling in Peripheral Artery Disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2018

Seahorse XFe96 Extracellular Flux Analyzer

EquipmentMajor User · Awarded by North Carolina Biotechnology Center · 2017 - 2018

Enhancing dendritic cell migration to drive potent anti-tumor immune responses

FellowshipMentor · Awarded by National Institutes of Health · 2013 - 2017

Tie2 Activation for the Treatment of Chemical-Induced Acute Lung Injury

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2016

Muscle-Resident Stem Cells for Angiogenesis and Vascular Maturation in PAD

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2016

Cancer Biology Training Grant

Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 1993 - 2016

Institutional Training Grant in Pediatric Cardiology

Inst. Training Prgm or CMEFaculty Member · Awarded by National Institutes of Health · 2009 - 2015

Novel pathways modulating Raf-mediated cardiac hypertrophy

ResearchCollaborator · Awarded by National Institutes of Health · 2013 - 2015

The role of satellite cells in adult skeletal muscle growth and maintenance

ResearchPrincipal Investigator · Awarded by University of Kentucky · 2013 - 2014

Peripheral endothelial and muscle cell pathology in cardiovascular disease

ResearchMentor · Awarded by National Institutes of Health · 2010 - 2013

PTEN Gene Therapy for Vein Graft Disease

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2012

The Role of PTEN in Endothelial Biology

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2012

The Role of ADAM15 in sTie@ Shedding and Ischemic Angiogenesis

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2010

Systems Biology of Angiogenesis

ResearchInvestigator · Awarded by National Institutes of Health · 2006 - 2009

Endothelial Cell Molecular Alterations in Cancer

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2002 - 2008

Therapeutic Angiogenesis for Erectile Dysfunction

ResearchCo Investigator · Awarded by National Institutes of Health · 2004 - 2008

The Role of Tie2 and the Angiopoietins in EPC Biology

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2005 - 2007

Downregulation of Tie2

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2004 - 2007

The Angiopoietins in Vascular Maintenance and Remodeling

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2002 - 2007

TIE2-Associated Molecular Targets in Tumor Vasculature

ResearchCo Investigator · Awarded by National Institutes of Health · 2002 - 2005

Endothelial signal transduction by tek and tie

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 2002

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ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1996 - 2002

Endothelial Signal Transduction By Tek And Tie

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1997 - 1999

Tek Signaling And Endothelial Biology

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1996 - 1999

External Relationships


  • ICON Clinical Research Limited

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.