Current Appointments & Affiliations
Associate Professor Emeritus
·
2021 - Present
Surgery, Surgical Sciences,
Surgery
Recent Publications
Immunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques.
Journal Article Sci Immunol · August 30, 2024 Adolescents are a growing population of people living with HIV. The period between weaning and sexual debut presents a low-risk window for HIV acquisition, making early childhood an ideal time for implementing an immunization regimen. Because the elicitati ... Full text Link to item CiteInnate protection against intrarectal SIV acquisition by a live SHIV vaccine.
Journal Article JCI Insight · May 21, 2024 Identifying immune correlates of protection is a major challenge in AIDS vaccine development. Anti-Envelope antibodies have been considered critical for protection against SIV/HIV (SHIV) acquisition. Here, we evaluated the efficacy of an SHIV vaccine again ... Full text Link to item CiteIntradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques.
Journal Article Nat Commun · August 8, 2023 Route of immunization can markedly influence the quality of immune response. Here, we show that intradermal (ID) but not intramuscular (IM) modified vaccinia Ankara (MVA) vaccinations provide protection from acquisition of intravaginal tier2 simian-human i ... Full text Link to item CiteRecent Grants
Primate Contract Expansion for Covid-19
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2021Nonhuman Primate Option 9
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2021HVTN Laboratory Center: HVTN 704
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Research Center · 2015 - 2020View All Grants
Education, Training & Certifications
University of Pennsylvania ·
1994
Ph.D.