Current Duke Appointments & Affiliations
Associate Professor Emeritus
·
2021 - Present
Surgery, Surgical Sciences,
Surgery
Recent Scholarly Works
Functional Convergence of Genetically Diverse B-Cell Receptors in Simian-HIV Infected Rhesus Macaques.
Preprint · January 12, 2026 Germline-targeting or lineage-design vaccine strategies are being used to induce HIV broadly neutralizing antibody (bnAb) responses. These strategies assume that genetically diverse individuals respond similarly to the same immunogen by mobilizing comparab ... Full text Link to item CiteImmunization with germ line-targeting SOSIP trimers elicits broadly neutralizing antibody precursors in infant macaques.
Journal article Sci Immunol · August 30, 2024 Adolescents are a growing population of people living with HIV. The period between weaning and sexual debut presents a low-risk window for HIV acquisition, making early childhood an ideal time for implementing an immunization regimen. Because the elicitati ... Full text Link to item CiteInnate protection against intrarectal SIV acquisition by a live SHIV vaccine.
Journal article JCI Insight · May 21, 2024 Identifying immune correlates of protection is a major challenge in AIDS vaccine development. Anti-Envelope antibodies have been considered critical for protection against SIV/HIV (SHIV) acquisition. Here, we evaluated the efficacy of an SHIV vaccine again ... Full text Link to item CiteRecent Grants
Primate Contract Expansion for Covid-19
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2021Nonhuman Primate Option 9
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2018 - 2021HVTN Laboratory Center: HVTN 704
ResearchInvestigator · Awarded by Fred Hutchinson Cancer Research Center · 2015 - 2020View All Grants
Education
University of Pennsylvania ·
1994
Ph.D.