Celia Crane LaBranche | Scholars@Duke

Celia Crane LaBranche
Associate Professor in Surgery

Current Appointments & Affiliations

Associate Professor in Surgery, Surgery, Surgical Sciences, Surgery 2017

Contact Information

205 Surg Oncol Res Fac, 915 S. Lasalle Street, Durham, NC 27710
Box 2926 Med Ctr, Durham, NC 27710
celia.labranche@duke.edu (919) 684-9986

Background
Education, Training, & Certifications
- Ph.D., University of Pennsylvania 1994
Duke Appointment History
- Assistant Professor of Surgery, Surgery, Surgical Sciences, Surgery 2013 - 2017
- Assistant Professor of Surgery, Surgery, Surgical Sciences, Surgery 2010 - 2013
- Adjunct Assistant Professor in the Department of Surgery, Surgery, Surgical Sciences, Surgery 2003 - 2010
- Assistant Research Professor in Surgery, Surgery, Surgical Sciences, Surgery 1999 - 2003
Research
Selected Grants
- Nonhuman Primate Core awarded by National Institutes of Health 2018 - 2019
- HIV Vaccine Trials Network: LC P5 PF awarded by Fred Hutchinson Cancer Research Center 2015 - 2018
- Nonhuman Primate Core-Option 6 awarded by National Institutes of Health 2012 - 2018
- LC: HIV Vaccine Trials Network: Phase 1 PF awarded by Fred Hutchinson Cancer Research Center 2015 - 2017
- LC: HIV Vaccine Trials Network awarded by Fred Hutchinson Cancer Research Center 2006 - 2017
- HIV Vaccine Trials Network: LC P5 PF awarded by Fred Hutchinson Cancer Research Center 2014 - 2015
- LC: HIV Vaccine Trials Network: Phase 1 PF awarded by Fred Hutchinson Cancer Research Center 2014 - 2015
- TM-SU Interaction in the Native HIV/SIV Env awarded by National Institutes of Health 2001 - 2008
- Host Virus Interactions During Acute Infection awarded by National Institutes of Health 1997 - 2002
- Analysis Of A Cd4-Independent Hiv-1/Iiib Envelope awarded by National Institutes of Health 1998 - 2001
- Peptides Models of Two Helical Regions in GP41 Ectodomain awarded by National Institutes of Health 1990 - 2000
Publications & Artistic Works
Selected Publications
- Book Sections
  - Hoxie, JA, LaBranche, CC, Endres, MJ, Turner, JD, Berson, JF, Doms, RW, and Matthews, TJ. "CD4(-) independent utilization of chemokine receptors by HIV-1 and HIV-2." 93-104. 1998. Link to Item
- Conference Papers
  - Reddy, PBJ, Gangadhara, S, Legere, T, Wehrle, B, Kovalenkov, Y, Spicer, LM, Kaja, M, Kasturi, SP, Labranche, CC, Kozlowski, PA, Wrammert, J, Derdeyn, CA, Montefiori, DC, Haynes, BF, Villinger, F, Pulendran, B, Hunter, E, and Amara, RR. "Effects of gp140 Protein Booster Immunizations to DNA/MVA SHIV Vaccine on Immunogenicity and Protection against Intravaginal Tier-2 SHIV Challenges." October 2016. Link to Item
  - Asbach, B, Koestler, J, Perdiguero, B, Esteban, M, Jacobs, BL, Montefiori, DC, LaBranche, CC, Yates, NL, Tomaras, GD, Ferrari, G, Foulds, KE, Roederer, M, Landucci, G, Forthal, DN, Seaman, MS, Hawkins, N, Self, SG, Phogat, S, Tartaglia, J, Barnett, SW, Burke, B, Cristillo, AD, Ding, S, Heeney, JL, Pantaleo, G, and Wagner, R. "Priming with a potent HIV-1 DNA vaccine frames the quality of T cell and antibody responses prior to a poxvirus and protein boost." September 26, 2016. Link to Item
  - Gautam, R, Nishimura, Y, Lee, WR, Donau, O, Buckler-White, A, Shingai, M, Sadjadpour, R, Schmidt, SD, LaBranche, CC, Keele, BF, Montefiori, D, Mascola, JR, and Martin, MA. "PATHOGENICITY AND MUCOSAL TRANSMISSIBILITY OF R5-TROPIC SIMIAN/HUMAN IMMUNODEFICIENCY VIRUSES SHIVAD8 IN RHESUS MACAQUES: IMPLICATIONS FOR THEIR USE IN VACCINE STUDIES." October 2013. Link to Item
  - Shingai, M, Donau, OK, Schmidt, SD, Gautam, R, Plishka, RJ, Buckler-White, A, Sadjadpour, R, Lee, W, LaBranche, CC, Montefiori, D, Mascola, JR, Nishimura, Y, and Martin, MA. "THE VAST MAJORITY OF RHESUS MACAQUES INFECTED WITH THE R5-TROPIC SHIVAD8 GENERATE CROSS-REACTIVE ANTIBODIES THAT NEUTRALIZE MULTIPLE HIV-1 STRAINS." October 2013. Link to Item
  - Alexander, J, Gurwith, M, Mendy, J, Vang, L, Manayani, D, Avanzini, J, Guenther, B, Farness, P, Haynes, BF, Liao, H, Montefiori, DC, LaBranche, CC, and Mayall, T. "Development of a HIV-1 vaccine using an orally-administered, replication-competent adenovirus serotype 4 vector expressing Env clade C glycoprotein." September 13, 2012. Link to Item
  - Sarzotti-Kelsoe, M, Daniell, X, Todd, CA, Bilska, M, LaBranche, C, Perez, LG, Ochsenbauer, C, Kappes, J, Rountree, W, Ozaki, DA, Kim, JH, McLinden, R, Denny, T, and Montefiori, DC. "Optimization and validation of the HIV-1 neutralizing antibody assay in A3R5 cells." September 13, 2012. Full Text Open Access Copy Link to Item
  - Kitrinos, KM, Irlbeck, DM, LaBranche, CC, Madsen, HA, and Demarest, JF. "Virological characterization of treatment naive subjects failing an aplaviroc-based regimen with either lamivudine/zidovudine or lopinavir/ritonavir." 2006. Link to Item
  - LaBranche, CC, Davison, D, Ferris, RG, Koszalka, GW, Demarest, JF, Boone, LR, and Greenberg, ML. "Studies with 873140, a novel CCR5 antagonist, demonstrate synergy with enfuvirtide and potent inhibition of enfuvirtide-resistant R5-tropic HIV-1." 2005. Link to Item
  - LaBranche, CC, Davison, D, Ferris, RG, Koszalka, GW, Demarest, JF, Boone, LR, and Greenberg, ML. "Studies with 873140, a novel CCR5 antagonist, demonstrate synergy with enfuvirtide and potent inhibition of enfuvirtide-resistant R5-tropic HIV-1." 2005. Link to Item
  - LABRANCHE, CC, HART, TK, BUGELSKI, PJ, JAMESON, BA, VARNUM, J, and HOXIE, JA. "ALTERATIONS IN THE CYTOPLASMIC TAIL OF SIV TRANSMEMBRANE MOLECULE ASSOCIATED WITH INCREASED INFECTIVITY AND SURFACE ENV EXPRESSION." March 29, 1993. Link to Item
  - LABRANCHE, CC, HART, TK, BUGELSKI, PJ, and HOXIE, JA. "CHANGES IN THE ENVELOPE GLYCOPROTEINS ARE ASSOCIATED WITH INFECTIVITY OF SIV AND DOWN-MODULATION OF CD4." May 1992. Link to Item
- Journal Articles
  - Jones, AT, Chamcha, V, Kesavardhana, S, Shen, X, Beaumont, D, Das, R, Wyatt, LS, LaBranche, CC, Stanfield-Oakley, S, Ferrari, G, Montefiori, DC, Moss, B, Tomaras, GD, Varadarajan, R, and Amara, RR. "A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques." Journal of virology 92, no. 5 (March 2018). Full Text
  - Klasse, PJ, Ketas, TJ, Cottrell, CA, Ozorowski, G, Debnath, G, Camara, D, Francomano, E, Pugach, P, Ringe, RP, LaBranche, CC, van Gils, MJ, Bricault, CA, Barouch, DH, Crotty, S, Silvestri, G, Kasturi, S, Pulendran, B, Wilson, IA, Montefiori, DC, Sanders, RW, Ward, AB, and Moore, JP. "Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques." PLoS pathogens 14, no. 2 (February 23, 2018): e1006913-. Full Text
  - de Taeye, SW, de la Peña, AT, Vecchione, A, Scutigliani, E, Sliepen, K, Burger, JA, van der Woude, P, Schorcht, A, Schermer, EE, van Gils, MJ, LaBranche, CC, Montefiori, DC, Wilson, IA, Moore, JP, Ward, AB, and Sanders, RW. "Stabilization of the gp120 V3 loop through hydrophobic interactions reduces the immunodominant V3-directed non-neutralizing response to HIV-1 envelope trimers." The Journal of biological chemistry 293, no. 5 (February 2018): 1688-1701. Full Text
  - Torrents de la Peña, A, de Taeye, SW, Sliepen, K, LaBranche, CC, Burger, JA, Schermer, EE, Montefiori, DC, Moore, JP, Klasse, PJ, and Sanders, RW. "Immunogenicity in rabbits of SOSIP trimers from clades A, B and C, given individually, sequentially or in combinations." Journal of virology (January 24, 2018). Full Text
  - Hogan, MJ, Conde-Motter, A, Jordan, APO, Yang, L, Cleveland, B, Guo, W, Romano, J, Ni, H, Pardi, N, LaBranche, CC, Montefiori, DC, Hu, S-L, Hoxie, JA, and Weissman, D. "Increased surface expression of HIV-1 envelope is associated with improved antibody response in vaccinia prime/protein boost immunization." Virology 514 (January 2018): 106-117. Full Text
  - Hraber, P, Rademeyer, C, Williamson, C, Seaman, MS, Gottardo, R, Tang, H, Greene, K, Gao, H, LaBranche, C, Mascola, JR, Morris, L, Montefiori, DC, and Korber, B. "Correction for Hraber et al., "Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments"." Journal of virology 92, no. 1 (January 2018). Full Text
  - Malherbe, DC, Mendy, J, Vang, L, Barnette, PT, Reed, J, Lakhashe, SK, Owuor, J, Gach, JS, Legasse, AW, Axthelm, MK, LaBranche, CC, Montefiori, D, Forthal, DN, Park, B, Wilson, JM, McLinden, JH, Xiang, J, Stapleton, JT, Sacha, JB, Haynes, BF, Liao, H-X, Ruprecht, RM, Smith, J, Gurwith, M, Haigwood, NL, and Alexander, J. "Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge." Journal of virology 92, no. 2 (January 2018). Full Text
  - Brocca-Cofano, E, Kuhrt, D, Siewe, B, Xu, C, Haret-Richter, GS, Craigo, J, Labranche, C, Montefiori, DC, Landay, A, Apetrei, C, and Pandrea, I. "Pathogenic Correlates of Simian Immunodeficiency Virus-Associated B Cell Dysfunction." Journal of virology 91, no. 23 (December 2017). Full Text
  - Cai, H, Orwenyo, J, Giddens, JP, Yang, Q, Zhang, R, LaBranche, CC, Montefiori, DC, and Wang, L-X. "Synthetic Three-Component HIV-1 V3 Glycopeptide Immunogens Induce Glycan-Dependent Antibody Responses." Cell chemical biology 24, no. 12 (December 2017): 1513-1522.e4. Full Text
  - Shen, X, Basu, R, Sawant, S, Beaumont, D, Kwa, SF, LaBranche, C, Seaton, KE, Yates, NL, Montefiori, DC, Ferrari, G, Wyatt, LS, Moss, B, Alam, SM, Haynes, BF, Tomaras, GD, and Robinson, HL. "HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine." Journal of virology 91, no. 24 (December 2017). Full Text
  - Hraber, P, Rademeyer, C, Williamson, C, Seaman, MS, Gottardo, R, Tang, H, Greene, K, Gao, H, LaBranche, C, Mascola, JR, Morris, L, Montefiori, DC, and Korber, B. "Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments." Journal of virology 91, no. 19 (October 2017). Full Text
  - Shen, X, Bogers, WM, Yates, NL, Ferrari, G, Dey, AK, Williams, WT, Jaeger, FH, Wiehe, K, Sawant, S, Alam, SM, LaBranche, CC, Montefiori, DC, Martin, L, Srivastava, I, Heeney, J, Barnett, SW, and Tomaras, GD. "Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques." Journal of virology 91, no. 19 (October 2017). Full Text
  - Del Prete, GQ, Keele, BF, Fode, J, Thummar, K, Swanstrom, AE, Rodriguez, A, Raymond, A, Estes, JD, LaBranche, CC, Montefiori, DC, KewalRamani, VN, Lifson, JD, Bieniasz, PD, and Hatziioannou, T. "A single gp120 residue can affect HIV-1 tropism in macaques." PLoS pathogens 13, no. 9 (September 25, 2017): e1006572-. Full Text
  - Menon, V, Ayala, VI, Rangaswamy, SP, Kalisz, I, Whitney, S, Galmin, L, Ashraf, A, LaBranche, C, Montefiori, D, Petrovsky, N, Kalyanaraman, VS, and Pal, R. "DNA prime/protein boost vaccination elicits robust humoral response in rhesus macaques using oligomeric simian immunodeficiency virus envelope and Advax delta inulin adjuvant." The Journal of general virology 98, no. 8 (August 2017): 2143-2155. Full Text
  - Parsons, MS, Lloyd, SB, Lee, WS, Kristensen, AB, Amarasena, T, Center, RJ, Keele, BF, Lifson, JD, LaBranche, CC, Montefiori, D, Wines, BD, Hogarth, PM, Swiderek, KM, Venturi, V, Davenport, MP, and Kent, SJ. "Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection." Science translational medicine 9, no. 402 (August 2017). Full Text
  - Ringe, RP, Ozorowski, G, Rantalainen, K, Struwe, WB, Matthews, K, Torres, JL, Yasmeen, A, Cottrell, CA, Ketas, TJ, LaBranche, CC, Montefiori, DC, Cupo, A, Crispin, M, Wilson, IA, Ward, AB, Sanders, RW, Klasse, PJ, and Moore, JP. "Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers." Journal of virology 91, no. 15 (August 2017). Full Text
  - Torrents de la Peña, A, Julien, J-P, de Taeye, SW, Garces, F, Guttman, M, Ozorowski, G, Pritchard, LK, Behrens, A-J, Go, EP, Burger, JA, Schermer, EE, Sliepen, K, Ketas, TJ, Pugach, P, Yasmeen, A, Cottrell, CA, Torres, JL, Vavourakis, CD, van Gils, MJ, LaBranche, C, Montefiori, DC, Desaire, H, Crispin, M, Klasse, PJ, Lee, KK, Moore, JP, Ward, AB, Wilson, IA, and Sanders, RW. "Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization." Cell reports 20, no. 8 (August 2017): 1805-1817. Full Text
  - Wang, C, Jiang, C, Gao, N, Zhang, K, Liu, D, Wang, W, Cong, Z, Qin, C, Ganusov, VV, Ferrari, G, LaBranche, C, Montefiori, DC, Kong, W, Yu, X, and Gao, F. "Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine." Viruses 9, no. 6 (June 2, 2017). Full Text
  - Pauthner, M, Havenar-Daughton, C, Sok, D, Nkolola, JP, Bastidas, R, Boopathy, AV, Carnathan, DG, Chandrashekar, A, Cirelli, KM, Cottrell, CA, Eroshkin, AM, Guenaga, J, Kaushik, K, Kulp, DW, Liu, J, McCoy, LE, Oom, AL, Ozorowski, G, Post, KW, Sharma, SK, Steichen, JM, de Taeye, SW, Tokatlian, T, Torrents de la Peña, A, Butera, ST, LaBranche, CC, Montefiori, DC, Silvestri, G, Wilson, IA, Irvine, DJ, Sanders, RW, Schief, WR, Ward, AB, Wyatt, RT, Barouch, DH, Crotty, S, and Burton, DR. "Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches." Immunity 46, no. 6 (June 2017): 1073-1088.e6. Full Text
  - Shubin, Z, Li, W, Poonia, B, Ferrari, G, LaBranche, C, Montefiori, D, Zhu, X, and Pauza, CD. "An HIV Envelope gp120-Fc Fusion Protein Elicits Effector Antibody Responses in Rhesus Macaques." Clinical and vaccine immunology : CVI 24, no. 6 (June 2017). Full Text
  - Zurawski, G, Shen, X, Zurawski, S, Tomaras, GD, Montefiori, DC, Roederer, M, Ferrari, G, Lacabaratz, C, Klucar, P, Wang, Z, Foulds, KE, Kao, S-F, Yu, X, Sato, A, Yates, NL, LaBranche, C, Stanfield-Oakley, S, Kibler, K, Jacobs, B, Salazar, A, Self, S, Fulp, W, Gottardo, R, Galmin, L, Weiss, D, Cristillo, A, Pantaleo, G, and Levy, Y. "Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses." Journal of virology 91, no. 9 (May 2017). Full Text
  - Capucci, S, Wee, EG, Schiffner, T, LaBranche, CC, Borthwick, N, Cupo, A, Dodd, J, Dean, H, Sattentau, Q, Montefiori, D, Klasse, PJ, Sanders, RW, Moore, JP, and Hanke, T. "HIV-1-neutralizing antibody induced by simian adenovirus- and poxvirus MVA-vectored BG505 native-like envelope trimers." PloS one 12, no. 8 (January 2017): e0181886-. Full Text
  - Kesavardhana, S, Das, R, Citron, M, Datta, R, Ecto, L, Srilatha, NS, DiStefano, D, Swoyer, R, Joyce, JG, Dutta, S, LaBranche, CC, Montefiori, DC, Flynn, JA, and Varadarajan, R. "Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies." The Journal of biological chemistry 292, no. 1 (January 2017): 278-291. Full Text
  - McCurley, NP, Domi, A, Basu, R, Saunders, KO, LaBranche, CC, Montefiori, DC, Haynes, BF, and Robinson, HL. "HIV transmitted/founder vaccines elicit autologous tier 2 neutralizing antibodies for the CD4 binding site." PloS one 12, no. 10 (January 2017): e0177863-. Full Text
  - Pahar, B, Kenway-Lynch, CS, Marx, P, Srivastav, SK, LaBranche, C, Montefiori, DC, and Das, A. "Breadth and magnitude of antigen-specific antibody responses in the control of plasma viremia in simian immunodeficiency virus infected macaques." Virology journal 13, no. 1 (December 2016): 200-. Full Text
  - Kannanganat, S, Wyatt, LS, Gangadhara, S, Chamcha, V, Chea, LS, Kozlowski, PA, LaBranche, CC, Chennareddi, L, Lawson, B, Reddy, PBJ, Styles, TM, Vanderford, TH, Montefiori, DC, Moss, B, Robinson, HL, and Amara, RR. "High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques." Journal of immunology (Baltimore, Md. : 1950) 197, no. 9 (November 2016): 3586-3596. Full Text
  - Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." Molecular therapy : the journal of the American Society of Gene Therapy 24, no. 11 (November 2016): 2021-2032. Full Text Open Access Copy
  - Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." MOLECULAR THERAPY 24, no. 11 (November 2016): 2021-2032. Full Text Open Access Copy Link to Item
  - Poteet, E, Lewis, P, Chen, C, Ho, SO, Do, T, Chiang, S, Labranche, C, Montefiori, D, Fujii, G, and Yao, Q. "Toll-like receptor 3 adjuvant in combination with virus-like particles elicit a humoral response against HIV." Vaccine 34, no. 48 (November 2016): 5886-5894. Full Text
  - Andersson, A-MC, Ragonnaud, E, Seaton, KE, Sawant, S, Folgori, A, Colloca, S, Labranche, C, Montefiori, DC, Tomaras, GD, and Holst, PJ. "Effect of HIV-1 envelope cytoplasmic tail on adenovirus primed virus encoded virus-like particle immunizations." Vaccine 34, no. 44 (October 2016): 5344-5351. Full Text
  - Iyer, SS, Gangadhara, S, Victor, B, Shen, X, Chen, X, Nabi, R, Kasturi, SP, Sabula, MJ, Labranche, CC, Reddy, PBJ, Tomaras, GD, Montefiori, DC, Moss, B, Spearman, P, Pulendran, B, Kozlowski, PA, and Amara, RR. "Virus-Like Particles Displaying Trimeric Simian Immunodeficiency Virus (SIV) Envelope gp160 Enhance the Breadth of DNA/Modified Vaccinia Virus Ankara SIV Vaccine-Induced Antibody Responses in Rhesus Macaques." Journal of virology 90, no. 19 (October 2016): 8842-8854. Full Text
  - Townsley, S, Mohamed, Z, Guo, W, McKenna, J, Cleveland, B, LaBranche, C, Beaumont, D, Shen, X, Yates, NL, Pinter, A, Tomaras, GD, Ferrari, G, Montefiori, DC, and Hu, S-L. "Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization." Journal of virology 90, no. 19 (October 2016): 8644-8660. Full Text
  - Klasse, PJ, LaBranche, CC, Ketas, TJ, Ozorowski, G, Cupo, A, Pugach, P, Ringe, RP, Golabek, M, van Gils, MJ, Guttman, M, Lee, KK, Wilson, IA, Butera, ST, Ward, AB, Montefiori, DC, Sanders, RW, and Moore, JP. "Sequential and Simultaneous Immunization of Rabbits with HIV-1 Envelope Glycoprotein SOSIP.664 Trimers from Clades A, B and C." PLoS pathogens 12, no. 9 (September 14, 2016): e1005864-. Full Text
  - Boehme, KW, Ikizler, M, Iskarpatyoti, JA, Wetzel, JD, Willis, J, Crowe, JE, LaBranche, CC, Montefiori, DC, Wilson, GJ, and Dermody, TS. "Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1." mSphere 1, no. 3 (May 18, 2016). Full Text
  - Swanstrom, AE, Haggarty, B, Jordan, APO, Romano, J, Leslie, GJ, Aye, PP, Marx, PA, Lackner, AA, Del Prete, GQ, Robinson, JE, Betts, MR, Montefiori, DC, LaBranche, CC, and Hoxie, JA. "Derivation and Characterization of a CD4-Independent, Non-CD4-Tropic Simian Immunodeficiency Virus." Journal of virology 90, no. 10 (May 2016): 4966-4980. Full Text
  - Willis, JR, Finn, JA, Briney, B, Sapparapu, G, Singh, V, King, H, LaBranche, CC, Montefiori, DC, Meiler, J, and Crowe, JE. "Long antibody HCDR3s from HIV-naïve donors presented on a PG9 neutralizing antibody background mediate HIV neutralization." Proceedings of the National Academy of Sciences of the United States of America 113, no. 16 (April 4, 2016): 4446-4451. Full Text
  - Asbach, B, Kliche, A, Köstler, J, Perdiguero, B, Esteban, M, Jacobs, BL, Montefiori, DC, LaBranche, CC, Yates, NL, Tomaras, GD, Ferrari, G, Foulds, KE, Roederer, M, Landucci, G, Forthal, DN, Seaman, MS, Hawkins, N, Self, SG, Sato, A, Gottardo, R, Phogat, S, Tartaglia, J, Barnett, SW, Burke, B, Cristillo, AD, Weiss, DE, Francis, J, Galmin, L, Ding, S, Heeney, JL, Pantaleo, G, and Wagner, R. "Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens." Journal of virology 90, no. 8 (April 2016): 4133-4149. Full Text Open Access Copy
  - Hessell, AJ, Malherbe, DC, Pissani, F, McBurney, S, Krebs, SJ, Gomes, M, Pandey, S, Sutton, WF, Burwitz, BJ, Gray, M, Robins, H, Park, BS, Sacha, JB, LaBranche, CC, Fuller, DH, Montefiori, DC, Stamatatos, L, Sather, DN, and Haigwood, NL. "Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens." Journal of immunology (Baltimore, Md. : 1950) 196, no. 7 (April 2016): 3064-3078. Full Text
  - Jeffries, TL, Sacha, CR, Pollara, J, Himes, J, Jaeger, FH, Dennison, SM, McGuire, E, Kunz, E, Eudailey, JA, Trama, AM, LaBranche, C, Fouda, GG, Wiehe, K, Montefiori, DC, Haynes, BF, Liao, H-X, Ferrari, G, Alam, SM, Moody, MA, and Permar, SR. "The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells." Mucosal immunology 9, no. 2 (March 2016): 414-427. Full Text
  - Khattar, SK, DeVico, AL, LaBranche, CC, Panda, A, Montefiori, DC, and Samal, SK. "Enhanced Immune Responses to HIV-1 Envelope Elicited by a Vaccine Regimen Consisting of Priming with Newcastle Disease Virus Expressing HIV gp160 and Boosting with gp120 and SOSIP gp140 Proteins." Journal of virology 90, no. 3 (February 2016): 1682-1686. Full Text
  - Chamcha, V, Kannanganat, S, Gangadhara, S, Nabi, R, Kozlowski, PA, Montefiori, DC, LaBranche, CC, Wrammert, J, Keele, BF, Balachandran, H, Sahu, S, Lifton, M, Santra, S, Basu, R, Moss, B, Robinson, HL, and Amara, RR. "Strong, but Age-Dependent, Protection Elicited by a Deoxyribonucleic Acid/Modified Vaccinia Ankara Simian Immunodeficiency Virus Vaccine." Open forum infectious diseases 3, no. 1 (January 2016): ofw034-. Full Text
  - Khattar, SK, Palaniyandi, S, Samal, S, LaBranche, CC, Montefiori, DC, Zhu, X, and Samal, SK. "Evaluation of humoral, mucosal, and cellular immune responses following co-immunization of HIV-1 Gag and Env proteins expressed by Newcastle disease virus (vol 11, pg 504, 2015)." HUMAN VACCINES & IMMUNOTHERAPEUTICS 12, no. 4 (2016): 1087-1087. Full Text Link to Item
  - Rosenberg, YJ, Montefiori, DC, LaBranche, CC, Lewis, MG, Sack, M, Lees, JP, and Jiang, X. "Protection against SHIV Challenge by Subcutaneous Administration of the Plant-Derived PGT121 Broadly Neutralizing Antibody in Macaques." PloS one 11, no. 3 (January 2016): e0152760-. Full Text
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  - Bhattacharyya, S, Singh, P, Rathore, U, Purwar, M, Wagner, D, Arendt, H, DeStefano, J, LaBranche, CC, Montefiori, DC, Phogat, S, and Varadarajan, R. "Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies." J Biol Chem 288, no. 14 (April 5, 2013): 9815-9825. Full Text Link to Item
  - Alexander, J, Mendy, J, Vang, L, Avanzini, JB, Garduno, F, Manayani, DJ, Ishioka, G, Farness, P, Ping, L-H, Swanstrom, R, Parks, R, Liao, H-X, Haynes, BF, Montefiori, DC, LaBranche, C, Smith, J, Gurwith, M, and Mayall, T. "Pre-clinical development of a recombinant, replication-competent adenovirus serotype 4 vector vaccine expressing HIV-1 envelope 1086 clade C." PloS one 8, no. 12 (January 2013): e82380-. Full Text
  - Kassa, A, Dey, AK, Sarkar, P, Labranche, C, Go, EP, Clark, DF, Sun, Y, Nandi, A, Hartog, K, Desaire, H, and al, E. "Stabilizing Exposure of Conserved Epitopes by Structure Guided Insertion of Disulfide Bond in HIV-1 Envelope Glycoprotein." PLoS ONE 8, no. 10 (2013). Full Text
  - Khattar, SK, Samal, S, LaBranche, CC, Montefiori, DC, Collins, PL, and Samal, SK. "Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector. (Published online)" PLoS One 8, no. 10 (2013): e78521-. Full Text Link to Item
  - McLinden, RJ, Labranche, CC, Chenine, A-L, Polonis, VR, Eller, MA, Wieczorek, L, Ochsenbauer, C, Kappes, JC, Perfetto, S, Montefiori, DC, Michael, NL, and Kim, JH. "Detection of HIV-1 neutralizing antibodies in a human CD4⁺/CXCR4⁺/CCR5⁺ T-lymphoblastoid cell assay system. (Published online)" PLoS One 8, no. 11 (2013): e77756-. Full Text Link to Item
  - Shytaj, IL, Chirullo, B, Wagner, W, Ferrari, MG, Sgarbanti, R, Corte, AD, LaBranche, C, Lopalco, L, Palamara, AT, Montefiori, D, Lewis, MG, Garaci, E, and Savarino, A. "Investigational treatment suspension and enhanced cell-mediated immunity at rebound followed by drug-free remission of simian AIDS." Retrovirology 10, no. 1 (2013). Full Text
  - Shingai, M, Donau, OK, Schmidt, SD, Gautam, R, Plishka, RJ, Buckler-White, A, Sadjadpour, R, Lee, WR, LaBranche, CC, Montefiori, DC, Mascola, JR, Nishimura, Y, and Martin, MA. "Most rhesus macaques infected with the CCR5-tropic SHIV(AD8) generate cross-reactive antibodies that neutralize multiple HIV-1 strains." Proc Natl Acad Sci U S A 109, no. 48 (November 27, 2012): 19769-19774. Full Text Link to Item
  - Jalah, R, Patel, V, Kulkarni, V, Rosati, M, Alicea, C, Ganneru, B, von Gegerfelt, A, Huang, W, Guan, Y, Broderick, KE, Sardesai, NY, LaBranche, C, Montefiori, DC, Pavlakis, GN, and Felber, BK. "IL-12 DNA as molecular vaccine adjuvant increases the cytotoxic T cell responses and breadth of humoral immune responses in SIV DNA vaccinated macaques." Hum Vaccin Immunother 8, no. 11 (November 1, 2012): 1620-1629. Full Text Link to Item
  - Gautam, R, Nishimura, Y, Lee, WR, Donau, O, Buckler-White, A, Shingai, M, Sadjadpour, R, Schmidt, SD, LaBranche, CC, Keele, BF, Montefiori, D, Mascola, JR, and Martin, MA. "Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies." J Virol 86, no. 16 (August 2012): 8516-8526. Full Text Link to Item
  - Montefiori, DC, Karnasuta, C, Huang, Y, Ahmed, H, Gilbert, P, de Souza, MS, McLinden, R, Tovanabutra, S, Laurence-Chenine, A, Sanders-Buell, E, Moody, MA, Bonsignori, M, Ochsenbauer, C, Kappes, J, Tang, H, Greene, K, Gao, H, LaBranche, CC, Andrews, C, Polonis, VR, Rerks-Ngarm, S, Pitisuttithum, P, Nitayaphan, S, Kaewkungwal, J, Self, SG, Berman, PW, Francis, D, Sinangil, F, Lee, C, Tartaglia, J, Robb, ML, Haynes, BF, Michael, NL, and Kim, JH. "Magnitude and breadth of the neutralizing antibody response in the RV144 and Vax003 HIV-1 vaccine efficacy trials." J Infect Dis 206, no. 3 (August 1, 2012): 431-441. Full Text Link to Item
  - Van Rompay, KKA, Trott, KA, Jayashankar, K, Geng, Y, LaBranche, CC, Johnson, JA, Landucci, G, Lipscomb, J, Tarara, RP, Canfield, DR, Heneine, W, Forthal, DN, Montefiori, D, and Abel, K. "Prolonged tenofovir treatment of macaques infected with K65R reverse transcriptase mutants of SIV results in the development of antiviral immune responses that control virus replication after drug withdrawal. (Published online)" Retrovirology 9 (July 17, 2012): 57-. Full Text Link to Item
  - Schell, JB, Bahl, K, Rose, NF, Buonocore, L, Hunter, M, Marx, PA, LaBranche, CC, Montefiori, DC, and Rose, JK. "Viral vectored granulocyte-macrophage colony stimulating factor inhibits vaccine protection in an SIV challenge model: protection correlates with neutralizing antibody." Vaccine 30, no. 28 (June 13, 2012): 4233-4239. Full Text Link to Item
  - Kobie, JJ, Alcena, DC, Zheng, B, Bryk, P, Mattiacio, JL, Brewer, M, Labranche, C, Young, FM, Dewhurst, S, Montefiori, DC, Rosenberg, AF, Feng, C, Jin, X, Keefer, MC, and Sanz, I. "9G4 autoreactivity is increased in HIV-infected patients and correlates with HIV broadly neutralizing serum activity." PLoS One 7, no. 4 (2012): e35356-. Full Text Link to Item
  - Lai, RPJ, Seaman, MS, Tonks, P, Wegmann, F, Seilly, DJ, Frost, SDW, LaBranche, CC, Montefiori, DC, Dey, AK, Srivastava, IK, Sattentau, Q, Barnett, SW, and Heeney, JL. "Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants." PLoS One 7, no. 4 (2012): e35083-. Full Text Link to Item
  - Clayton, R, Hardman, J, LaBranche, CC, and McReynolds, KD. "Evaluation of the synthesis of sialic acid-PAMAM glycodendrimers without the use of sugar protecting groups, and the anti-HIV-1 properties of these compounds." Bioconjug Chem 22, no. 10 (October 19, 2011): 2186-2197. Full Text Link to Item
  - Tang, H, Robinson, JE, Gnanakaran, S, Li, M, Rosenberg, ES, Perez, LG, Haynes, BF, Liao, H-X, Labranche, CC, Korber, BT, and Montefiori, DC. "epitopes immediately below the base of the V3 loop of gp120 as targets for the initial autologous neutralizing antibody response in two HIV-1 subtype B-infected individuals." J Virol 85, no. 18 (September 2011): 9286-9299. Full Text Link to Item
  - Tilton, JC, Amrine-Madsen, H, Miamidian, JL, Kitrinos, KM, Pfaff, J, Demarest, JF, Ray, N, Jeffrey, JL, Labranche, CC, and Doms, RW. "HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry." AIDS Res Hum Retroviruses 26, no. 1 (January 2010): 13-24. Full Text Link to Item
  - Irlbeck, DM, Amrine-Madsen, H, Kitrinos, KM, Labranche, CC, and Demarest, JF. "Chemokine (C-C motif) receptor 5-using envelopes predominate in dual/mixed-tropic HIV from the plasma of drug-naive individuals." AIDS 22, no. 12 (July 31, 2008): 1425-1431. Full Text Link to Item
  - Yuan, X, Huang, L, Ho, P, Labranche, C, and Chen, CH. "Conformation of gp120 determines the sensitivity of HIV-1 DH012 to the entry inhibitor IC9564." Virology 324, no. 2 (July 1, 2004): 525-530. Full Text Link to Item
  - Liu, J, Wang, S, Hoxie, JA, LaBranche, CC, and Lu, M. "Mutations that destabilize the gp41 core are determinants for stabilizing the simian immunodeficiency virus-CPmac envelope glycoprotein complex." J Biol Chem 277, no. 15 (April 12, 2002): 12891-12900. Full Text Link to Item
  - Edwards, TG, Hoffman, TL, Baribaud, F, Wyss, S, LaBranche, CC, Romano, J, Adkinson, J, Sharron, M, Hoxie, JA, and Doms, RW. "Relationships between CD4 independence, neutralization sensitivity, and exposure of a CD4-induced epitope in a human immunodeficiency virus type 1 envelope protein." J Virol 75, no. 11 (June 2001): 5230-5239. Full Text Link to Item
  - LaBranche, CC, Galasso, G, Moore, JP, Bolognesi, DP, Hirsch, MS, and Hammer, SM. "HIV fusion and its inhibition." Antiviral Res 50, no. 2 (May 2001): 95-115. (Review) Link to Item
  - Martín, J, LaBranche, CC, and González-Scarano, F. "Differential CD4/CCR5 utilization, gp120 conformation, and neutralization sensitivity between envelopes from a microglia-adapted human immunodeficiency virus type 1 and its parental isolate." J Virol 75, no. 8 (April 2001): 3568-3580. Full Text Link to Item
  - LaBranche, CC, Hoffman, TL, Romano, J, Haggarty, BS, Edwards, TG, Matthews, TJ, Doms, RW, and Hoxie, JA. "Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity." J Virol 73, no. 12 (December 1999): 10310-10319. Link to Item
  - Hoffman, TL, LaBranche, CC, Zhang, W, Canziani, G, Robinson, J, Chaiken, I, Hoxie, JA, and Doms, RW. "Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein." Proc Natl Acad Sci U S A 96, no. 11 (May 25, 1999): 6359-6364. Link to Item
  - Hoxie, JA, LaBranche, CC, Endres, MJ, Turner, JD, Berson, JF, Doms, RW, and Matthews, TJ. "CD4-independent utilization of the CXCR4 chemokine receptor by HIV-1 and HIV-2." J Reprod Immunol 41, no. 1-2 (December 1998): 197-211. (Review) Link to Item
  - Sauter, MM, Pelchen-Matthews, A, Bron, R, Marsh, M, LaBranche, CC, Vance, PJ, Romano, J, Haggarty, BS, Hart, TK, Lee, WM, and Hoxie, JA. "An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface." J Cell Biol 132, no. 5 (March 1996): 795-811. Link to Item
  - LaBranche, CC, Sauter, MM, Haggarty, BS, Vance, PJ, Romano, J, Hart, TK, Bugelski, PJ, Marsh, M, and Hoxie, JA. "A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells." J Virol 69, no. 9 (September 1995): 5217-5227. Link to Item
  - LaBranche, CC, Sauter, MM, Haggarty, BS, Vance, PJ, Romano, J, Hart, TK, Bugelski, PJ, and Hoxie, JA. "Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus." J Virol 68, no. 9 (September 1994): 5509-5522. Link to Item
  - LaBranche, CC, Clark, SC, Johnson, GD, Ornstein, D, Sabath, DE, Tushinski, R, Paetkau, V, and Prystowsky, MB. "Deletion of carboxy-terminal residues of murine granulocyte-macrophage colony-stimulating factor results in a loss of biologic activity and altered glycosylation." Arch Biochem Biophys 276, no. 1 (January 1990): 153-159. Link to Item
- Other Articles
  - Fouts, TR, Bagley, K, Prado, IJ, Bobb, KL, Schwartz, JA, Xu, R, Zagursky, RJ, Egan, MA, Eldridge, JH, LaBranche, CC, Montefiori, DC, Le Buanec, H, Zagury, D, Pal, R, Pavlakis, GN, Felber, BK, Franchini, G, Gordon, S, Vaccari, M, Lewis, GK, DeVico, AL, and Gallo, RC. "Correction: Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection (Proceedings National Academy Sciences USA (2015) 112 (E992-E999) DOI: 10.1073/pnas.1423669112)." Proceedings of the National Academy of Sciences of the United States of America 112, no. 18 (May 5, 2015): E2413-. Full Text
  - Chakrabarti, BK, Feng, Y, Sharma, SK, McKee, K, Karlsson Hedestam, GB, LaBranche, CC, Montefiori, DC, Mascola, JR, and Wyatt, RT. "Correction for Chakrabarti et al., Robust Neutralizing Antibodies Elicited by HIV-1 JRFL Envelope Glycoprotein Trimers in Nonhuman Primates." Journal of virology 89, no. 1 (January 2015): 887-. Full Text
  - Han, D, Habte, H, Qin, Y, Takamoto, K, LaBranche, C, Montefiori, D, and Cho, M. "Retraction: eliciting broadly neutralizing antibodies against HIV-1 that target gp41 MPER." Retrovirology 11, no. 1 (2014): 16-16. Full Text
  - Khattar, SK, Samal, S, Labranche, CC, Montefiori, DC, Collins, PL, and Samal, SK. "Correction: Comparative Immunogenicity of HIV-1 gp160, gp140 and gp120 Expressed by Live Attenuated Newcastle Disease Virus Vector." PloS one 9, no. 1 (2014). Full Text
  - LaBranche, CC, Sauter, MM, Haggarty, BS, Vance, PJ, Romano, J, Hart, TK, Bugelski, PJ, and Hoxie, JA. "Biological, molecular, and structural analysis of a cytopathic variant from a molecularly cloned simian immunodeficiency virus." J Virol 68, no. 11 (November 1994): 7665-7667. Link to Item

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