Scholars@Duke

• Research
• 

  Selected Grants

  • Novel Immunogens to Elicit Broadly Cross-reactive Antibodies That Target the Hemagglutinin Head Trimer Interface awarded by National Institutes of Health 2021 - 2025
  • SHIV/HIV Env-Antibody Coevolution as a Guide to Iterative Vaccine Design awarded by University of Pennsylvania 2017 - 2023
  • Immunity to novel T/F SHIVs: variability in the co-evolution of virus and host immunity awarded by National Institutes of Health 2017 - 2022
  • Modeling affinity maturation at molecular resolution awarded by Boston University 2015 - 2020
  • Testing the Nearest Neighbor Approach to Active Vaccination for HIV-1 awarded by University of Washington 2014 - 2017
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Kuraoka, Masayuki, Chen-Hao Yeh, Goran Bajic, Ryutaro Kotaki, Shengli Song, Ian Windsor, Stephen C. Harrison, and Garnett Kelsoe. “Recall of B cell memory depends on relative locations of prime and boost immunization.” Sci Immunol 7, no. 71 (May 6, 2022): eabn5311. https://doi.org/10.1126/sciimmunol.abn5311.
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    • Yeh, Chen-Hao, Joel Finney, Takaharu Okada, Tomohiro Kurosaki, and Garnett Kelsoe. “Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells.” Immunity 55, no. 2 (February 8, 2022): 272-289.e7. https://doi.org/10.1016/j.immuni.2021.12.015.
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    • Bradley, Todd, Masayuki Kuraoka, Chen-Hao Yeh, Ming Tian, Huan Chen, Derek W. Cain, Xuejun Chen, et al. “Immune checkpoint modulation enhances HIV-1 antibody induction.” Nat Commun 11, no. 1 (February 19, 2020): 948. https://doi.org/10.1038/s41467-020-14670-w.
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    • Finney, Joel, Chen-Hao Yeh, Garnett Kelsoe, and Masayuki Kuraoka. “Germinal center responses to complex antigens.” Immunol Rev 284, no. 1 (July 2018): 42–50. https://doi.org/10.1111/imr.12661.
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    • Yeh, Chen-Hao, Takuya Nojima, Masayuki Kuraoka, and Garnett Kelsoe. “Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density.” Nat Commun 9, no. 1 (March 2, 2018): 928. https://doi.org/10.1038/s41467-018-03382-x.
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    • Wheaton, Joshua D., Chen-Hao Yeh, and Maria Ciofani. “Cutting Edge: c-Maf Is Required for Regulatory T Cells To Adopt RORγt+ and Follicular Phenotypes.” J Immunol 199, no. 12 (December 15, 2017): 3931–36. https://doi.org/10.4049/jimmunol.1701134.
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    • Su, Kuei-Ying, Akiko Watanabe, Chen-Hao Yeh, Garnett Kelsoe, and Masayuki Kuraoka. “Efficient Culture of Human Naive and Memory B Cells for Use as APCs.” J Immunol 197, no. 10 (November 15, 2016): 4163–76. https://doi.org/10.4049/jimmunol.1502193.
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    • Wang, Hsi-Kai, Chen-Hao Yeh, Taku Iwamoto, Hideo Satsu, Makoto Shimizu, and Mamoru Totsuka. “Dietary flavonoid naringenin induces regulatory T cells via an aryl hydrocarbon receptor mediated pathway.” Journal of Agricultural and Food Chemistry 60, no. 9 (March 2012): 2171–78. https://doi.org/10.1021/jf204625y.
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    • Yeh, Chen-Hao, Hsiao-Chin Chen, Jeng-Je Yang, Wen-I Chuang, and Fuu Sheu. “Polysaccharides PS-G and protein LZ-8 from Reishi (Ganoderma lucidum) exhibit diverse functions in regulating murine macrophages and T lymphocytes.” Journal of Agricultural and Food Chemistry 58, no. 15 (August 2010): 8535–44. https://doi.org/10.1021/jf100914m.
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    • Chang, Hui-Hsin, Kuang-Yang Hsieh, Chen-Hao Yeh, Yuan-Ping Tu, and Fuu Sheu. “Oral administration of an Enoki mushroom protein FVE activates innate and adaptive immunity and induces anti-tumor activity against murine hepatocellular carcinoma.” International Immunopharmacology 10, no. 2 (February 2010): 239–46. https://doi.org/10.1016/j.intimp.2009.10.017.
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    • Yeh, C. H., J. K. Hsiao, J. L. Wang, and F. Sheu. “Immunological impact of magnetic nanoparticles (Ferucarbotran) on murine peritoneal macrophages.” Journal of Nanoparticle Research 12, no. 1 (January 1, 2010): 151–60. https://doi.org/10.1007/s11051-009-9589-y.
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    • Chang, Hui-Hsin, Chen-Hao Yeh, and Fuu Sheu. “A novel immunomodulatory protein from Poria cocos induces Toll-like receptor 4-dependent activation within mouse peritoneal macrophages.” Journal of Agricultural and Food Chemistry 57, no. 14 (July 2009): 6129–39. https://doi.org/10.1021/jf9011399.
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    • Yeh, Chen-Hao, Joel Finney, Takaharu Okada, Tomohiro Kurosaki, and Garnett Kelsoe. “Germinal Center Resident T _FH are a Small, Physiologically Distinct Subset of CXCR5 ^hiPD-1 ^hi T _FH (Accepted).” Ssrn Electronic Journal, n.d. https://doi.org/10.2139/ssrn.3737146.
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