Bradley Henry Collins
Associate Professor of Surgery
(1) The laboratory's primary focus is the study of the feasibility of transplanting porcine islets into primates as a treatment for type 1 diabetes mellitus. There is a severe shortage of human cadaveric pancreas donors for the 1 to 2 million type 1 diabetics in the United States. The use of human islets would further exacerbate the problem as 2 or 3 pancreases are required per recipient. In collaboration with Dr. Emmanuel Opara, an islet cell physiologist, we have purified islets from porcine pancreases, placed the islets in microcapsules, and transplanted the islets into diabetic baboons without the use of immunosuppression. Our goal is to demonstrated the utility of this system as a pre-clinical model.
(2) Recently, my laboratory has developed an interest in senescence of the liver. The project is a collaborative effort with hepatologist Dr. Don Rockey. We induce cirrhosis in young and old mice with carbon tetrachloride and then extract the intrahepatic lymphocytes. FACS technology is used to identified the lymphocyte populations and then sort them. The cytokine profile is then elucidated. We plan to use gene chip technology to assess the gene expression.
(2) Recently, my laboratory has developed an interest in senescence of the liver. The project is a collaborative effort with hepatologist Dr. Don Rockey. We induce cirrhosis in young and old mice with carbon tetrachloride and then extract the intrahepatic lymphocytes. FACS technology is used to identified the lymphocyte populations and then sort them. The cytokine profile is then elucidated. We plan to use gene chip technology to assess the gene expression.
Current Appointments & Affiliations
- Associate Professor of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2021
Contact Information
- Box 3512 Med Ctr, Durham, NC 27710
- Hanes House, Trent Drive, Durham, NC 27710
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colli005@mc.duke.edu
(919) 681-3855
- Background
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Education, Training, & Certifications
- Fellow, Surgery, University of Wisconsin - Madison 1997 - 1999
- Chief Resident, Surgery, Duke University 1996 - 1997
- Senior Assistant Resident, Surgery, Duke University 1994 - 1996
- Research Fellow, Surgery, Duke University 1991 - 1994
- Junior Assistant Resident, Surgery, Duke University 1990 - 1991
- Intern, Surgery, Duke University 1989 - 1990
- M.D., Duke University 1989
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Duke Appointment History
- Associate Professor of Surgery, Surgery, Abdominal Transplant Surgery, Surgery 2011 - 2020
- Associate Professor of Surgery, Surgery, Section of Surgical Disciplines 2010 - 2011
- Associate Professor of Surgery, Surgery, Section of Surgical Disciplines 2008 - 2009
- Assistant Professor of Surgery, Surgery, Section of Surgical Disciplines 1999 - 2008
- Instructor, Temporary in the Department of Surgery, Surgery, Section of Surgical Disciplines 1999
- Research
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Selected Grants
- Neonatal porcine islet xenografts for the treatment of type 1 diabetes awarded by National Institutes of Health 2014 - 2025
- Transplant Tolerance in Non-Human Primates awarded by Emory University 2014 - 2017
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Halpern, Samantha E., Dimitrios Moris, Brian I. Shaw, Samuel J. Kesseli, Mariya L. Samoylova, Miriam Manook, Robin Schmitz, et al. “Definition and Analysis of Textbook Outcome: A Novel Quality Measure in Kidney Transplantation.” World J Surg, January 23, 2021. https://doi.org/10.1007/s00268-020-05943-y.Full Text Link to Item
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Schroder, Paul M., Robin Schmitz, Zachary W. Fitch, Brian Ezekian, Janghoon Yoon, Ashley Y. Choi, Miriam Manook, et al. “Preoperative carfilzomib and lulizumab based desensitization prolongs graft survival in a sensitized non-human primate model.” Kidney Int 99, no. 1 (January 2021): 161–72. https://doi.org/10.1016/j.kint.2020.08.020.Full Text Link to Item
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McElroy, Lisa M., Scott L. Sanoff, and Bradley H. Collins. “Kidney transplant in the COVID era: Cautious optimism and continued vigilance.” Am J Transplant 20, no. 11 (November 2020): 2971–72. https://doi.org/10.1111/ajt.16190.Full Text Link to Item
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Ezekian, Brian, Paul M. Schroder, Michael S. Mulvihill, Andrew Barbas, Bradley Collins, Kyle Freischlag, Janghoon Yoon, et al. “Pretransplant Desensitization with Costimulation Blockade and Proteasome Inhibitor Reduces DSA and Delays Antibody-Mediated Rejection in Highly Sensitized Nonhuman Primate Kidney Transplant Recipients.” J Am Soc Nephrol 30, no. 12 (December 2019): 2399–2411. https://doi.org/10.1681/ASN.2019030304.Full Text Link to Item
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Samy, Kannan P., Qimeng Gao, Robert Patrick Davis, Mingqing Song, Zachary W. Fitch, Michael S. Mulvihill, Andrea L. MacDonald, et al. “The role of human CD46 in early xenoislet engraftment in a dual transplant model.” Xenotransplantation 26, no. 6 (November 2019): e12540. https://doi.org/10.1111/xen.12540.Full Text Link to Item
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Aminsharifi, Alireza, Ross Simon, Thomas J. Polascik, Cary N. Robertson, Debra L. Sudan, Bradley H. Collins, and Judd W. Moul. “Evaluation and Active Treatment versus Active Surveillance of Localized Prostate Cancer in Renal Transplant Patients in the Era of Low and Very Low Risk Prostate Cancer.” J Urol 202, no. 3 (September 2019): 469–74. https://doi.org/10.1097/JU.0000000000000207.Full Text Link to Item
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Mulvihill, Michael S., Kannan P. Samy, Qimeng A. Gao, Robin Schmitz, Robert P. Davis, Brian Ezekian, Francis Leopardi, et al. “Secondary lymphoid tissue and costimulation-blockade resistant rejection: A nonhuman primate renal transplant study.” Am J Transplant 19, no. 8 (August 2019): 2350–57. https://doi.org/10.1111/ajt.15365.Full Text Link to Item
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Kwun, Jean, Marie Matignon, Miriam Manook, Soulef Guendouz, Vincent Audard, David Kheav, Elsa Poullot, et al. “Daratumumab in Sensitized Kidney Transplantation: Potentials and Limitations of Experimental and Clinical Use.” J Am Soc Nephrol 30, no. 7 (July 2019): 1206–19. https://doi.org/10.1681/ASN.2018121254.Full Text Link to Item
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Samy, K. P., R. P. Davis, Q. Gao, B. M. Martin, M. Song, J. Cano, A. B. Farris, et al. “Early barriers to neonatal porcine islet engraftment in a dual transplant model.” Am J Transplant 18, no. 4 (April 2018): 998–1006. https://doi.org/10.1111/ajt.14601.Full Text Link to Item
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Song, M., M. S. Mulvihill, K. D. Williams, B. H. Collins, and A. D. Kirk. “Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque.” J Med Primatol 47, no. 1 (February 2018): 81–84. https://doi.org/10.1111/jmp.12285.Full Text Link to Item
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Samy, K. P., D. J. Anderson, D. J. Lo, M. S. Mulvihill, M. Song, A. B. Farris, B. S. Parker, et al. “Selective Targeting of High-Affinity LFA-1 Does Not Augment Costimulation Blockade in a Nonhuman Primate Renal Transplantation Model.” Am J Transplant 17, no. 5 (May 2017): 1193–1203. https://doi.org/10.1111/ajt.14141.Full Text Link to Item
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Davis, Bradley, Daniele Marin, Lynne M. Hurwitz, James Ronald, Matthew J. Ellis, Kadiyala V. Ravindra, Bradley H. Collins, and Charles Y. Kim. “Application of a Novel CT-Based Iliac Artery Calcification Scoring System for Predicting Renal Transplant Outcomes.” Ajr Am J Roentgenol 206, no. 2 (February 2016): 436–41. https://doi.org/10.2214/AJR.15.14794.Full Text Link to Item
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Martin, B. M., K. P. Samy, M. C. Lowe, P. W. Thompson, J. Cano, A. B. Farris, M. Song, et al. “Dual islet transplantation modeling of the instant blood-mediated inflammatory reaction.” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, no. 5 (May 2015): 1241–52. https://doi.org/10.1111/ajt.13098.Full Text
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Yurcisin, Basil M., Tara E. Davison, Syreena M. Bibbs, Bradley H. Collins, Jonathan S. Stamler, and James D. Reynolds. “Repletion of S-nitrosohemoglobin improves organ function and physiological status in swine after brain death.” Annals of Surgery 257, no. 5 (May 2013): 971–77. https://doi.org/10.1097/sla.0b013e3182822c52.Full Text
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Barbas, A. S., A. S. Rege, A. W. Castleberry, J. Gommer, M. J. Ellis, T. V. Brennan, B. H. Collins, et al. “Posterior reversible encephalopathy syndrome independently associated with tacrolimus and sirolimus after multivisceral transplantation.” American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons 13, no. 3 (March 2013): 808–10. https://doi.org/10.1111/ajt.12061.Full Text
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Ravindra, K. V., A. E. Martin, D. S. Vikraman, T. V. Brennan, B. H. Collins, A. S. Rege, S. T. Hollenbeck, et al. “Use of vascularized posterior rectus sheath allograft in pediatric multivisceral transplantation--report of two cases.” Am J Transplant 12, no. 8 (August 2012): 2242–46. https://doi.org/10.1111/j.1600-6143.2012.04088.x.Full Text Link to Item
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Alexander, B. D., W. A. Schell, A. M. Siston, C. Y. Rao, W. A. Bower, S. A. Balajee, D. N. Howell, et al. “Fatal Apophysomyces elegans infection transmitted by deceased donor renal allografts.” Am J Transplant 10, no. 9 (September 2010): 2161–67. https://doi.org/10.1111/j.1600-6143.2010.03216.x.Full Text Link to Item
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Barbas, A. S., T. E. Sweeney, B. H. Collins, P. C. Kuo, J. E. Tuttle-Newhall, D. L. Sudan, and C. E. Marroquin. “Kidney-pancreas transplantation in the setting of donor ethylene glycol poisoning.” Dialysis and Transplantation 39, no. 5 (May 1, 2010): 216–17. https://doi.org/10.1002/dat.20440.Full Text
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Tracy, Elisabeth T., Kyla M. Bennett, Emeline M. Aviki, Theodore N. Pappas, Bradley H. Collins, Janet E. Tuttle-Newhall, Carlos E. Marroquin, Paul C. Kuo, and John E. Scarborough. “Temporal trends in liver transplant centre volume in the USA.” Hpb (Oxford) 11, no. 5 (August 2009): 414–21. https://doi.org/10.1111/j.1477-2574.2009.00075.x.Full Text Link to Item
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Scarborough, John E., Ricardo Pietrobon, Janet E. Tuttle-Newhall, Carlos E. Marroquin, Bradley H. Collins, Dev M. Desai, Paul C. Kuo, and Theodore N. Pappas. “Relationship between provider volume and outcomes for orthotopic liver transplantation.” J Gastrointest Surg 12, no. 9 (September 2008): 1527–33. https://doi.org/10.1007/s11605-008-0589-5.Full Text Link to Item
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Barbas, A. S., T. E. Downing, K. R. Balsara, H. E. Tan, G. J. Rubinstein, Z. E. Holzknecht, B. H. Collins, W. Parker, R. D. Davis, and S. S. Lin. “Chronic aspiration shifts the immune response from Th1 to Th2 in a murine model of asthma.” Eur J Clin Invest 38, no. 8 (August 2008): 596–602. https://doi.org/10.1111/j.1365-2362.2008.01976.x.Full Text Link to Item
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Li, B., M. G. Hartwig, J. Z. Appel, E. L. Bush, K. R. Balsara, Z. E. Holzknecht, B. H. Collins, et al. “Chronic aspiration of gastric fluid induces the development of obliterative bronchiolitis in rat lung transplants.” Am J Transplant 8, no. 8 (August 2008): 1614–21. https://doi.org/10.1111/j.1600-6143.2008.02298.x.Full Text Link to Item
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Scarborough, J. E., J. E. Tuttle-Newhall, R. Pietrobon, C. E. Marroquin, B. H. Collins, D. M. Desai, P. C. Kuo, and T. N. Pappas. “Supply and demand for liver transplant surgery: are we training enough surgeons?” Hpb (Oxford) 10, no. 1 (2008): 25–29. https://doi.org/10.1080/13651820701883098.Full Text Link to Item
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Scarborough, John E., Ricardo Pietrobon, Carlos E. Marroquin, Janet E. Tuttle-Newhall, Paul C. Kuo, Bradley H. Collins, Dev M. Desai, and Theodore N. Pappas. “Temporal trends in early clinical outcomes and health care resource utilization for liver transplantation in the United States.” J Gastrointest Surg 11, no. 1 (January 2007): 82–88. https://doi.org/10.1007/s11605-007-0103-5.Full Text Link to Item
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Hanish, S. I., R. P. Petersen, B. H. Collins, J. Tuttle-Newhall, C. E. Marroquin, P. C. Kuo, D. W. Butterly, S. R. Smith, and D. M. Desai. “Obesity predicts increased overall complications following pancreas transplantation.” Transplant Proc 37, no. 8 (October 2005): 3564–66. https://doi.org/10.1016/j.transproceed.2005.09.068.Full Text Link to Item
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Marroquin, Carlos E., Erick B. Edwards, Bradley H. Collins, Dev M. Desai, Janet E. Tuttle-Newhall, and Paul C. Kuo. “Half-life analysis of pancreas and kidney transplants.” Transplantation 80, no. 2 (July 27, 2005): 272–75. https://doi.org/10.1097/01.tp.0000165094.94020.03.Full Text Link to Item
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Smith, Alastair D., Diane Bai, Carlos E. Marroquin, Janet E. Tuttle-Newhall, Dev M. Desai, Bradley H. Collins, Andrew Muir, Paul C. Kuo, John McHutchison, and Don C. Rockey. “Gastrointestinal hemorrhage due to complicated gastroduodenal ulcer disease in liver transplant patients taking sirolimus.” Clin Transplant 19, no. 2 (April 2005): 250–54. https://doi.org/10.1111/j.1399-0012.2005.00332.x.Full Text Link to Item
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Collins, Bradley H., Carlos E. Marroquin, Janet E. Tuttle-Newhall, Paul C. Kuo, Glenn M. Preminger, and David W. Butterly. “Acute kidney transplant failure following transurethral bladder polyp fulguration.” J Natl Med Assoc 97, no. 3 (March 2005): 414–16.Link to Item
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Tuttle-Newhall, Janet E., Bradley H. Collins, Dev M. Desai, Paul C. Kuo, and Michael A. Heneghan. “The current status of living donor liver transplantation.” Curr Probl Surg 42, no. 3 (March 2005): 144–83. https://doi.org/10.1067/j.cpsurg.2004.12.003.Full Text Link to Item
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Kendall, W. F., M. D. Darrabie, H. M. El-Shewy, and E. C. Opara. “Effect of alginate composition and purity on alginate microspheres.” Journal of Microencapsulation 21, no. 8 (December 2004): 821–28. https://doi.org/10.1080/02652040400015452.Full Text
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Schroeder, Rebecca A., Bradley H. Collins, Elizabeth Tuttle-Newhall, Kerri Robertson, Jeffrey Plotkin, Lynt B. Johnson, and Paul C. Kuo. “Intraoperative fluid management during orthotopic liver transplantation.” J Cardiothorac Vasc Anesth 18, no. 4 (August 2004): 438–41. https://doi.org/10.1053/j.jvca.2004.05.020.Full Text Link to Item
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El-Shewy, Hesham M., F Kendall William, Marcus Darrabie, Bradley H. Collins, and Emmanuel C. Opara. “Polyvinyl Pyrrolidone: A Novel Cryoprotectant in Islet Cell Cryopreservation.” Cell Transplant 13, no. 3 (April 2004): 237–43. https://doi.org/10.3727/000000004783983927.Full Text Link to Item
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Palestrant, Daniel, Zoie E. Holzknecht, Bradley H. Collins, William Parker, Sara E. Miller, and R Randal Bollinger. “Microbial biofilms in the gut: visualization by electron microscopy and by acridine orange staining.” Ultrastruct Pathol 28, no. 1 (January 2004): 23–27.Link to Item
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Rocha, Paulo N., David W. Butterly, Arthur Greenberg, Donal N. Reddan, Janet Tuttle-Newhall, Bradley H. Collins, Paul C. Kuo, et al. “Beneficial effect of plasmapheresis and intravenous immunoglobulin on renal allograft survival of patients with acute humoral rejection.” Transplantation 75, no. 9 (May 15, 2003): 1490–95. https://doi.org/10.1097/01.TP.0000060252.57111.AC.Full Text Link to Item
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Heneghan, Michael A., J Elizabeth Tuttle-Newhall, Paul V. Suhocki, Andrew J. Muir, Michael Morse, Jeffrey D. Bornstein, Pamela B. Sylvestre, Bradley Collins, Paul C. Kuo, and Don C. Rockey. “De-novo cholangiocarcinoma in the setting of recurrent primary sclerosing cholangitis following liver transplant.” Am J Transplant 3, no. 5 (May 2003): 634–38. https://doi.org/10.1034/j.1600-6143.2003.00110.x.Full Text Link to Item
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Tuttle-Newhall, Janet E., Bradley H. Collins, Paul C. Kuo, and Rebecca Schoeder. “Organ donation and treatment of the multi-organ donor.” Curr Probl Surg 40, no. 5 (May 2003): 266–310. https://doi.org/10.1016/S0011-3840(03)00011-X.Full Text Link to Item
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Dy-Liacco, Mariano S., Elizabeth J. Tuttle-Newhall, Bradley H. Collins, and Paul C. Kuo. “Liver transplantation from a cadaver donor with ethylene-glycol-induced brain death.” Transplantation 75, no. 7 (April 15, 2003): 1056. https://doi.org/10.1097/01.TP.0000058773.88045.11.Full Text Link to Item
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Marroquin, Carlos E., J Elizabeth Tuttle-Newhall, Bradley H. Collins, Paul C. Kuo, and Rebecca A. Schroeder. “Emergencies after liver transplantation.” Semin Gastrointest Dis 14, no. 2 (April 2003): 101–10.Link to Item
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Collins, B. H. “Porcine islets as an alternative to human islets for transplantation.” J Investig Med 49, no. 6 (November 2001): 576–79. https://doi.org/10.2310/6650.2001.33723.Full Text Link to Item
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Ching, C. D., R. C. Harland, B. H. Collins, W. Kendall, H. Hobbs, and E. C. Opara. “A reliable method for isolation of viable porcine islet cells.” Arch Surg 136, no. 3 (March 2001): 276–79. https://doi.org/10.1001/archsurg.136.3.276.Full Text Link to Item
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Kendall, W. F., B. H. Collins, and E. C. Opara. “Islet cell transplantation for the treatment of diabetes mellitus.” Expert Opin Biol Ther 1, no. 1 (January 2001): 109–19. https://doi.org/10.1517/14712598.1.1.109.Full Text Link to Item
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Kendall, W., M. Darrabie, B. Freeman, H. Hobbs, B. Collins, and E. Opara. “Effect of bead swelling on the durability of polylysine alginate microcapsules.” Current Surgery 57, no. 6 (November 2000): 636–37. https://doi.org/10.1016/s0149-7944(00)00354-8.Full Text
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Collins, B. H., J. D. Pirsch, Y. T. Becker, M. J. Hanaway, W. J. Van der Werf, A. M. D’Alessandro, S. J. Knechtle, et al. “Long-term results of liver transplantation in older patients 60 years of age and older.” Transplantation 70, no. 5 (September 15, 2000): 780–83. https://doi.org/10.1097/00007890-200009150-00012.Full Text Link to Item
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Clavien, P. A., P. Baron, B. Tuttle-Newhall, and B. H. Collins. “Contralateral inflow occlusion to optimize graft volume and to reduce blood loss during parenchymal dissection in living-related liver transplantation.” Transplantation 69, no. 10 (May 27, 2000): 2232. https://doi.org/10.1097/00007890-200005270-00054.Full Text Link to Item
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Becker, B. N., P. C. Brazy, Y. T. Becker, J. S. Odorico, T. J. Pintar, B. H. Collins, J. D. Pirsch, G. E. Leverson, D. M. Heisey, and H. W. Sollinger. “Simultaneous pancreas-kidney transplantation reduces excess mortality in type 1 diabetic patients with end-stage renal disease.” Kidney Int 57, no. 5 (May 2000): 2129–35. https://doi.org/10.1046/j.1523-1755.2000.00064.x.Full Text Link to Item
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Collins, B. H., W. F. Kendall, H. A. Hobbs, M. D. Darrabie, and E. C. Opara. “Microcapsule stabilization with sodium sulfate pretreatment.” Transplantation 69, no. 8 (April 27, 2000): S209–S209.Link to Item
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Becker, B. N., Y. T. Becker, T. J. Pintar, B. H. Collins, J. D. Pirsch, A. Friedman, H. W. Sollinger, and P. C. Brazy. “Using renal transplantation to evaluate a simple approach for predicting the impact of end-stage renal disease therapies on patient survival: observed/expected life span.” Am J Kidney Dis 35, no. 4 (April 2000): 653–59. https://doi.org/10.1016/s0272-6386(00)70012-6.Full Text Link to Item
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Foley, D. P., B. R. Collins, J. C. Magee, J. L. Platt, E. Katz, R. C. Harland, W. C. Meyers, and R. S. Chari. “Bile acids in xenogeneic ex-vivo liver perfusion: function of xenoperfused livers and compatibility with human bile salts and porcine livers.” Transplantation 69, no. 2 (January 2000): 242–48. https://doi.org/10.1097/00007890-200001270-00009.Full Text
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Becker, B. N., J. S. Odorico, Y. T. Becker, G. Leverson, J. C. McDermott, T. Grist, I. Sproat, et al. “Peripheral vascular disease and renal transplant artery stenosis: a reappraisal of transplant renovascular disease.” Clin Transplant 13, no. 4 (August 1999): 349–55. https://doi.org/10.1034/j.1399-0012.1999.130412.x.Full Text Link to Item
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Becker, B. N., Y. T. Becker, D. M. Heisey, G. E. Leverson, B. H. Collins, J. S. Odorico, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, and H. W. Sollinger. “The impact of hypoalbuminemia in kidney-pancreas transplant recipients.” Transplantation 68, no. 1 (July 15, 1999): 72–75. https://doi.org/10.1097/00007890-199907150-00014.Full Text Link to Item
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Becker, Y. T., M. Groshek, B. N. Becker, B. H. Collins, J. S. Odorico, M. Hanaway, J. D. Pirsch, S. J. Knechtle, A. M. D’Alessandro, and H. W. Sollinger. “A SURVEY OF MALE SEXUAL FUNCTION FOLLOWING PANCREAS TRANSPLANTATION.” Transplantation 67, no. 7 (April 1999): S174–S174. https://doi.org/10.1097/00007890-199904150-00697.Full Text
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D’Alessandro, A. M., J. D. Pirsch, S. J. Knechtle, J. S. Odorico, W. J. Van der Werf, B. H. Collins, Y. T. Becker, M. Kalayoglu, M. J. Armbrust, and H. W. Sollinger. “Living unrelated renal donation: the University of Wisconsin experience.” Surgery 124, no. 4 (October 1998): 604–10. https://doi.org/10.1067/msy.1998.91482.Full Text Link to Item
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Pruitt, S. K., R. R. Bollinger, B. H. Collins, H. C. Marsh, J. L. Levin, A. R. Rudolph, W. M. Baldwin, and F. Sanfilippo. “Effect of continuous complement inhibition using soluble complement receptor type 1 on survival of pig-to-primate cardiac xenografts.” Transplantation 63, no. 6 (March 27, 1997): 900–902. https://doi.org/10.1097/00007890-199703270-00017.Full Text Link to Item
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Odorico, J. S., Y. T. Becker, W. Van der Werf, B. Collins, A. M. D’Alessandro, S. J. Knechtle, J. D. Pirsch, and H. W. Sollinger. “Advances in pancreas transplantation: the University of Wisconsin experience.” Clin Transpl, 1997, 157–66.Link to Item
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Broome, A. H., G. M. Eisen, R. C. Harland, B. H. Collins, W. C. Meyers, and T. N. Pappas. “Quality of life after treatment for pancreatitis.” Ann Surg 223, no. 6 (June 1996): 665–70. https://doi.org/10.1097/00000658-199606000-00005.Full Text Link to Item
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Cotterell, A. H., B. H. Collins, W. Parker, R. C. Harland, and J. L. Platt. “The humoral immune response in humans following ex vivo perfusion of porcine livers.” Transplant Proc 28, no. 2 (April 1996): 546.Link to Item
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Pruitt, S. K., R. R. Bollinger, B. H. Collins, H. C. Marsh, J. L. Levin, A. R. Rudolph, W. M. Baldwin, and F. Sanfilippo. “Continuous complement (C) inhibition using soluble C receptor type 1 (sCR1): effect on hyperacute rejection (HAR) of pig-to-primate cardiac xenografts.” Transplant Proc 28, no. 2 (April 1996): 756.Link to Item
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Magee, J. C., B. H. Collins, R. C. Harland, B. J. Lindman, R. R. Bollinger, M. M. Frank, and J. L. Platt. “Immunoglobulin prevents complement-mediated hyperacute rejection in swine-to-primate xenotransplantation.” The Journal of Clinical Investigation 96, no. 5 (November 1995): 2404–12. https://doi.org/10.1172/jci118297.Full Text
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Cotterell, A. H., B. H. Collins, W. Parker, R. C. Harland, and J. L. Platt. “The humoral immune response in humans following cross-perfusion of porcine organs.” Transplantation 60, no. 8 (October 27, 1995): 861–68.Link to Item
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Alvarado, C. G., A. H. Cotterell, K. R. McCurry, B. H. Collins, J. C. Magee, J. Berthold, J. S. Logan, and J. L. Platt. “Variation in the level of xenoantigen expression in porcine organs.” Transplantation 59, no. 11 (June 15, 1995): 1589–96.Link to Item
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Collins, B. H., A. H. Cotterell, K. R. McCurry, C. G. Alvarado, J. C. Magee, W. Parker, and J. L. Platt. “Cardiac xenografts between primate species provide evidence for the importance of the alpha-galactosyl determinant in hyperacute rejection.” J Immunol 154, no. 10 (May 15, 1995): 5500–5510.Link to Item
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Collins, B. H., R. S. Chari, J. C. Magee, R. C. Harland, B. J. Lindman, J. S. Logan, R. R. Bollinger, W. C. Meyers, and J. L. Platt. “Immunopathology of porcine livers perfused with blood of humans with fulminant hepatic failure.” Transplantation Proceedings 27, no. 1 (February 1995): 280–81.
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Magee, J. C., B. H. Collins, R. C. Harland, R. R. Bollinger, M. M. Frank, and J. L. Platt. “Prevention of hyperacute xenograft rejection by intravenous immunoglobulin.” Transplant Proc 27, no. 1 (February 1995): 271.Link to Item
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Collins, B. H., R. S. Chari, J. C. Magee, R. C. Harland, B. J. Lindman, J. S. Logan, R. R. Bollinger, W. C. Meyers, and J. L. Platt. “Mechanisms of injury in porcine livers perfused with blood of patients with fulminant hepatic failure.” Transplantation 58, no. 11 (December 15, 1994): 1162–71.Link to Item
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Chari, R. S., B. H. Collins, J. C. Magee, J. M. DiMaio, A. D. Kirk, R. C. Harland, R. L. McCann, J. L. Platt, and W. C. Meyers. “Brief report: treatment of hepatic failure with ex vivo pig-liver perfusion followed by liver transplantation.” N Engl J Med 331, no. 4 (July 28, 1994): 234–37. https://doi.org/10.1056/NEJM199407283310404.Full Text Link to Item
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Pruitt, S. K., A. D. Kirk, R. R. Bollinger, H. C. Marsh, B. H. Collins, J. L. Levin, J. R. Mault, J. S. Heinle, S. Ibrahim, and A. R. Rudolph. “The effect of soluble complement receptor type 1 on hyperacute rejection of porcine xenografts.” Transplantation 57, no. 3 (February 1994): 363–70. https://doi.org/10.1097/00007890-199402150-00009.Full Text Link to Item
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Collins, B. H., W. Parker, and J. L. Piatt. “Characterization of porcine endothelial cell determinants recognized by human natural antibodies.” Xenotransplantation 1, no. 1 (January 1, 1994): 36–46. https://doi.org/10.1111/j.1399-3089.1994.tb00048.x.Full Text
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Collins, B. H., M. L. Areford, M. A. Fabian, B. D. Jaffee, and R. R. Bollinger. “Brequinar sodium potentiates the effects of cyclosporine in experimental small bowel transplantation.” Transplantation Proceedings 25, no. 3 Suppl 2 (June 1993): 37–39.
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Book Sections
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Ellis, M. J., B. H. Collins, B. Ezekian, and S. J. Knechtle. “Medical evaluation of the living donor.” In Kidney Transplantation - Principles and Practice, 104–14, 2019. https://doi.org/10.1016/B978-0-323-53186-3.00007-3.Full Text
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Bush, E. L., K. V. Ravindra, and B. H. Collins. “Surgical techniques: Pancreas transplantation.” In Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease, 639–46, 2013. https://doi.org/10.1142/9789814293068_0050.Full Text
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Lunsford, K. E., and B. H. Collins. “Pancreas and islet cell transplantation.” In Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease, 533–56, 2013. https://doi.org/10.1142/9789814293068_0043.Full Text
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Papalezova, K., C. E. Marroquin, B. H. Collins, J. E. Tuttle-Newhall, and P. C. Kuo. “Liver transplantation.” In Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease, 173–90, 2013. https://doi.org/10.1142/9789814293068_0012.Full Text
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Collins, B. H., and D. M. Desai. “Rejection.” In Medical Care of the Liver Transplant Patient: Third Edition, 304–22, 2007. https://doi.org/10.1002/9780470751541.ch19.Full Text
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Other Articles
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Lunsford, Keri E., Matthew T. Harris, Kimberly N. Nicoll, Bradley H. Collins, Debra L. Sudan, Paul C. Kuo, and Deepak Vikraman. “Single-site laparoscopic living donor nephrectomy offers comparable perioperative outcomes to conventional laparoscopic living donor nephrectomy at a higher cost.” Transplantation, January 27, 2011. https://doi.org/10.1097/TP.0b013e3181fecfe6.Full Text Link to Item
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Dy-Liacco, Mariano S., and Bradley H. Collins. “An alternate arterial reconstruction for pancreas transplantation.” Transplantation, February 15, 2004. https://doi.org/10.1097/01.TP.0000113161.85418.55.Full Text Link to Item
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Everett, Mary Lou, Bradley H. Collins, and William Parker. “Kupffer cells: another player in liver tolerance induction.” Liver Transpl, May 2003. https://doi.org/10.1053/jlts.2003.50092.Full Text Link to Item
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Conference Papers
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Fitch, Z. W., Q. Gao, R. P. Davis, M. S. Mulvihill, M. Song, F. Leopardi, M. Ribeiro, et al. “Islet Xenotransplantation: A Quest for Clinically Available Immunosuppression Regimens.” In American Journal of Transplantation, 19:473–74. WILEY, 2019.Link to Item
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Song, M., K. Samy, Q. Gao, R. P. Davis, F. Leopard, Z. Fitch, C. Bennett, G. R. Devi, B. H. Collins, and A. D. Kirk. “CD46 Transgene Modification and Thrombosis in Neonatal Porcine Islet Xenotransplantation.” In American Journal of Transplantation, 19:430–430. WILEY, 2019.Link to Item
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Harris, Matt T., B. H. Collins, D. Vikraman, A. E. Martin, T. V. Brennan, D. L. Sudan, and P. C. Kuo. “Sublingual Tacrolimus after High Risk Kidney Transplant.” In American Journal of Transplantation, 10:469–469. WILEY-BLACKWELL PUBLISHING, INC, 2010.Link to Item
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Vikraman, Deepak, Bradley H. Collins, Matthew T. Harris, Abigail E. Martin, Todd V. Brennan, Kimberly N. Nicoll, Debra L. Sudan, and Paul C. Kuo. “Single Incision Laparoscopic Donor Nephrectomy Offers No Advantage over Standard Laparoscopic Donor Nephrectomy.” In American Journal of Transplantation, 10:539–539. WILEY-BLACKWELL PUBLISHING, INC, 2010.Link to Item
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Chen, Dongfeng, Deepak Vikraman, Bradley H. Collins, Matthew T. Harris, and Janet E. Tuttle-Newhall. “Intracellular ATP Levels after Liver Transplant Are Associated with Fungal Infections and Increased Risk of Death.” In American Journal of Transplantation, 9:638–39. WILEY-BLACKWELL PUBLISHING, INC, 2009.Link to Item
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Marroquin, Carlos E., Marion K. Stewart, Barbara O. Burgess, Rebecca D. Nalley, Alastair Smith, Iliana Bouneva, Bradley H. Collins, et al. “Humoral Rejection after Liver Transplantation.” In American Journal of Transplantation, 9:532–33. WILEY-BLACKWELL PUBLISHING, INC, 2009.Link to Item
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Harris, Matt T., Erin L. McCann, Dev M. Desai, Brad H. Collins, Carlos E. Marroquin, Janet E. Tuttle-Newhall, and Paul C. Kuo. “Two-daclizumab vs two-dose basiliximab in high-risk kidney and kidney-pancreas transplant.” In American Journal of Transplantation, 7:521–521. BLACKWELL PUBLISHING, 2007.Link to Item
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Harris, Matt T., Pat L. Holl, Kyla M. Bennett, Brad H. Collins, Carlos E. Marroquin, John E. Scarborough, Janet E. Tuttle-Newhall, Paul C. Kuo, and Dev M. Desai. “Intra-operative aprotinin in liver transplant and renal dysfunction.” In American Journal of Transplantation, 7:473–74. BLACKWELL PUBLISHING, 2007.Link to Item
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Desai, D. M., J. E. Tuttle-Newhall, B. H. Collins, D. C. Rockey, C. Marroquin, P. C. Kuo, and A. D. Smith. “Aggressive recurrent HCV liver disease following liver transplantation in the absence of any immunosuppression.” In Liver Transplantation, 11:C76–C76. JOHN WILEY & SONS INC, 2005.Link to Item
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Collins, B. H., C. E. Marroquin, J. E. Tuttle-Newhall, D. M. Desai, S. R. Smith, D. W. Butterly, R. R. Bollinger, and P. C. Kuo. “The management of end stage renal disease in the recipients of extrarenal transplants.” In American Journal of Transplantation, 4:537–537. BLACKWELL MUNKSGAARD, 2004.Link to Item
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Elshewy, H., W. Kendall, M. Darrabie, B. H. Collins, and E. C. Opara. “Islet cell intregrity and function after freezing with various cryoprotectants.” In Cell Transplantation, 12:184–184. COGNIZANT COMMUNICATION CORP, 2003.Link to Item
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Stephenson, G. R., L. A. Szczech, B. H. Collins, P. C. Kuo, M. A. Hereghan, E. Moretti, and J. E. Tuttle-Newhall. “Mutivariate analysis of risk factors for chevron incisional hernia formation following liver transplantation.” In Hepatology, 36:672A-672A. W B SAUNDERS CO, 2002.Link to Item
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Tuttle-Newhall, J. E., B. H. Collins, S. N. Vaslef, P. C. Kuo, E. Piantadosi, G. R. Stephenson, M. A. Heneghan, and N. W. Knudsen. “The effect of pre-transplant MELD score on length of stay and hospital charges after orthotopic liver transplantation.” In Hepatology, 36:193A-193A. W B SAUNDERS CO, 2002.Link to Item
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Kendall, W. F., H. A. Hobbs, M. D. Darrabie, B. H. Collins, and E. C. Opara. “Alginate bead swelling and polymorphism: Effect of Na2SO4 treatment.” In Faseb Journal, 15:A727–A727. FEDERATION AMER SOC EXP BIOL, 2001.Link to Item
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Van der Werf, W. J., J. Odorico, A. M. D’Alessandro, S. Knechtle, Y. Becker, B. Collins, J. Pirsch, R. Hoffman, and H. W. Sollinger. “Utilization of pediatric donors for pancreas transplantation.” In Transplantation Proceedings, 31:610–11, 1999. https://doi.org/10.1016/s0041-1345(98)01578-4.Full Text
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BROOME, A. H., B. H. COLLINS, R. C. HARLAND, W. C. MEYERS, and T. N. PAPPAS. “QUALITY-OF-LIFE AFTER PANCREATIC DEBRIDEMENT.” In Gastroenterology, 108:A1214–A1214, 1995. https://doi.org/10.1016/0016-5085(95)29152-0.Full Text Link to Item
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