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Brian Gary Czito

Brian Gary Czito

Professor of Radiation Oncology
Radiation Oncology
Box 3085 Med Ctr, Durham, NC
05145B Morris Clinic, Durham, NC 27710

Overview

Listed in Best Doctors in America. Listed in Top Doctors in North Carolina. His research interests include gastrointestinal malignancies, including treatment and integration of novel systemic agents with radiation therapy in the treatment of esophageal, gastric, hepatobiliary, pancreatic, colorectal and anal malignancies; phase I/II clinical trials evaluating novel systemic/targeted agents in conjunction with radiation therapy; investigation and optimization of the treatment of gastrointestinal malignancies, with focus on the above tumor sites.

Current Appointments & Affiliations

Professor of Radiation Oncology · 2018 - Present Radiation Oncology, Clinical Science Departments
Member of the Duke Cancer Institute · 2001 - Present Duke Cancer Institute, Institutes and Centers

Recent Publications

Toxicity of Ablative Radiation Therapy in the Management of Patients with Child-Pugh B/C Liver Function and Unresectable Hepatocellular Carcinoma (HCC).

Journal Article Cancers (Basel) · February 19, 2026 BACKGROUND/OBJECTIVES: Hypofractionated ablative radiation is an increasingly popular option for patients with hepatocellular carcinoma (HCC). However, concern remains about the risk for radiation-induced liver toxicity in patients with decompensated liver ... Full text Link to item Cite

Pembrolizumab, Radiotherapy, and Chemotherapy in Neoadjuvant Treatment of Malignant Esophago-gastric Diseases (PROCEED): A single-arm phase 2 trial.

Journal Article Cancer · December 15, 2025 INTRODUCTION: Esophagogastric cancers are common and carry a poor prognosis. A standard option for locally advanced disease has been neoadjuvant chemoradiation (CRT) followed by surgical resection. The primary goal of this study was to investigate whether ... Full text Link to item Cite

Radiation Therapy for Anal Squamous Cell Carcinoma: An ASTRO Clinical Practice Guideline.

Journal Article Pract Radiat Oncol · 2025 PURPOSE: This guideline provides evidence-based recommendations addressing the indications for definitive treatment of primary squamous cell carcinoma of the anal canal and anal margin. METHODS: The American Society for Radiation Oncology convened a task f ... Full text Link to item Cite
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Recent Grants

Inhibition of CaMKK2 sensitizes rectal cancers to radiation therapy

ResearchCollaborator · Awarded by National Institutes of Health · 2021 - 2022

Knowledge-based Tutoring for Knowledge-based Radiation Therapy

ResearchCo Investigator · Awarded by Varian Medical Systems, Inc. · 2020 - 2022

View All Grants

Education

Medical College of Georgia · 1996 M.D.