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Daniel Friedman

Associate Professor of Medicine
Medicine, Cardiology
2301 Erwin Road, Suite 7451, Durham, NC 27701

Overview


My research areas of interest include improving the safety and efficacy of complex ablation and optimal use of pacemakers in patients with heart failure, including cardiac resynchronization therapy and conduction system pacing. I am also interested in non-pharmacologic management of atrial fibrillation, including catheter ablation and left atrial appendage occlusion, and understanding optimal use of novel and emerging technologies.

Current Duke Appointments & Affiliations


Associate Professor of Medicine · 2023 - Present Medicine, Cardiology, Medicine

Recent Scholarly Works


Preclinical evaluation of a novel 8-spline pulsed field ablation system.

Journal article Heart Rhythm · July 2026 BACKGROUND: Pulsed field ablation (PFA) technologies offer the potential for improved procedural efficacy and safety. Circumferential pulmonary vein (PV) ablation approaches are attractive compared with point-by-point, simplifying workflow. OBJECTIVE: We e ... Full text Link to item Cite

Outcomes of Patients With Reduced Left Ventricular Function Undergoing Left Atrial Appendage Occlusion.

Journal article JACC Clin Electrophysiol · May 25, 2026 BACKGROUND: Transcatheter left atrial appendage occlusion (LAAO) is an alternative treatment to prevent stroke in patients with atrial fibrillation. Patients with reduced left ventricular ejection fraction (LVEF) represent a particularly high-risk populati ... Full text Link to item Cite
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Recent Grants


Safety and Effectiveness of Left Bundle Branch Area Pacing versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Clinical TrialPrincipal Investigator · Awarded by Boston Scientific Corporation · 2026 - 2033

Fire-HFpEF

Clinical TrialPrincipal Investigator · Awarded by Medtronic, Inc. · 2024 - 2029

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Education


Cornell University, Weill Medical College · 2010 M.D.
Cornell University · 2006 B.S.
High School · 2002 C.