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David Andrew Brown

Associate Professor of Surgery
Surgery, Plastic, Maxillofacial, and Oral Surgery

Research Interests


Dr. Brown's research focuses on mechanisms of complex tissue regeneration in mammalian systems, including limb and digit regeneration as well as scarless wound healing. His lab utilizes transgenic mice, next-generating sequencing technologies, and gene therapy to both understand and manipulate regenerative processes in mammals. His work in regeneration biology is funded by the National Institutes of Health.

Selected Grants


Enhancing limb regeneration with gene therapy informed by comparative biology

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2029

Genetic approaches to skin regeneration in zebrafish

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2020 - 2025

2021 Duke Flap Course

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Checkpoint Surgical · 2021 - 2021

A point-of-care, biomarker-based test to predict non-healing in chronic wounds

ResearchPrincipal Investigator · Awarded by The Plastic Surgery Foundation · 2018 - 2020

Antibody-Mediated Inhibition of Tumor Necrosis Factor-Alpha in a Novel Wound Dressing for Hypertrophic Scars

ResearchPrincipal Investigator · Awarded by The Plastic Surgery Foundation · 2015 - 2017