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David Miller

Research Scientist
Biomedical Engineering

Overview


David studied biomedical engineering at Purdue University (BS '18) where he developed an interest in optical microscopy as an undergraduate research assistant in the Huang Group. After graduating, David joined the Functional Optical Imaging Lab (FOIL) at Northwestern University as a biomedical engineering graduate student (MS '20, PhD '23). At Northwestern, David focused on the development of visible-light optical coherence tomography (vis-OCT), and developed a novel extension of vis-OCT called vis-OCT fibergraphy, which enables in vivo visualization and quantification of retinal ganglion cell (RGC) axon bundles in the retina. In addition, David introduced techniques for improving noise suppression in OCT images. David joined the BIOS lab at Duke in 2023, where he focuses on research for low-cost OCT and spectroscopic OCT techniques.

Current Appointments & Affiliations


Recent Publications


Swept-source visible-light optical coherence tomography.

Journal Article Optics letters · February 2025 We demonstrate the feasibility of swept-source visible-light optical coherence tomography (SS-vis-OCT). We used a fanout periodically poled lithium niobate (PPLN) crystal for second-harmonic generation (SHG) to convert a commercial near-infrared swept-sour ... Full text Cite

Development of next generation low-cost OCT towards improved point-of-care retinal imaging.

Journal Article Biomedical optics express · February 2025 Low-cost optical coherence tomography (OCT) has shown promise in increasing access to noninvasive retinal imaging at the point of care, especially in low-resource environments. A next-generation low-cost OCT system is presented which improves performance o ... Full text Cite

Enhanced penetration depth in optical coherence tomography and photoacoustic microscopy in vivo enabled by absorbing dye molecules

Journal Article Optica · January 20, 2025 The scattering and absorption of light within biological tissue severely limits the penetration depth of optical imaging techniques. Recently, it has been found that water-soluble, strongly absorbing dye molecules, such as tartrazine, can achieve in vivo t ... Full text Cite
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Recent Grants


Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease

ResearchResearch Scientist · Awarded by National Institute on Aging · 2022 - 2027

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