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David Asher Leiman

Associate Professor of Medicine
Medicine, Gastroenterology

Overview


Dr. Leiman is an Associate Professor of Medicine and gastroenterologist specializing in esophageal diseases and swallowing disorders, such as eosinophilic esophagitis (EoE), motility disorders such as achalasia, and gastroesophageal reflux disease (GERD) as well as its associated complications including Barrett’s esophagus (BE). His busy clinical practice dovetails with his academic focus on health services research, including patient outcomes and clinical quality measurement. He is also a PI for several ongoing multicenter clinical trials investigating novel therapies for EoE and GERD.

Dr. Leiman has mentored numerous medical students, residents, and GI fellows on research and quality improvement projects resulting in research awards, presentations at national meetings, and peer-reviewed publications.

Current Appointments & Affiliations


Associate Professor of Medicine · 2023 - Present Medicine, Gastroenterology, Medicine
Member in the Duke Clinical Research Institute · 2017 - Present Duke Clinical Research Institute, Institutes and Centers
Member of the Duke Cancer Institute · 2018 - Present Duke Cancer Institute, Institutes and Centers

In the News


Published October 13, 2022
Expert Perspectives on PPI Prescribing & Monitoring Patterns
Published June 1, 2022
Many Studies of Digestive Diseases Fail to Examine Food Insecurity

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Recent Publications


AGA Clinical Practice Guideline on Surveillance of Barrett's Esophagus.

Journal Article Gastroenterology · November 2025 BACKGROUND & AIMS: Barrett's esophagus (BE) is the only identifiable precursor to esophageal adenocarcinoma (EAC). Endoscopic surveillance has been proposed for early detection of BE-related neoplasia and reducing EAC mortality. This clinical practice guid ... Full text Link to item Cite

AGA Clinical Practice Guideline on Management of Gastroparesis.

Journal Article Gastroenterology · October 2025 BACKGROUND & AIMS: Gastroparesis is a complex gastric motility disorder characterized by nausea, vomiting, and other symptoms associated with a delay in gastric emptying in the absence of mechanical obstruction. Variations in diagnostic testing and limited ... Full text Link to item Cite

Esophageal Expert Development of a Preliminary Question Prompt List for Adults With Eosinophilic Esophagitis: A Modified Delphi Study.

Journal Article J Clin Gastroenterol · July 1, 2025 BACKGROUND: Question prompt lists (QPLs) are structured sets of disease-specific questions intended to encourage question-asking by patients and enhance patient-physician communication. To date, an EoE-specific QPL has not been developed for EoE patients. ... Full text Link to item Cite
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Recent Grants


Dupixent Registry R668-EE-2328 EDESIA Pro00117064

Clinical TrialPrincipal Investigator · Awarded by Regeneron Pharmaceuticals, Inc. · 2025 - 2030

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Education, Training & Certifications


Vanderbilt University, School of Medicine · 2009 M.D.