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David Adam Mack

Associate Professor of Medicine
Medicine, Medical Oncology
2592 Morris Bldg, BOX_3395 Med Ctr, Durham, NC 27710

Current Appointments & Affiliations


Associate Professor of Medicine · 2023 - Present Medicine, Medical Oncology, Medicine

Recent Publications


Binding of rituximab, trastuzumab, cetuximab, or mAb T101 to cancer cells promotes trogocytosis mediated by THP-1 cells and monocytes.

Journal Article J Immunol · December 1, 2008 More than 20 years ago clinical investigations in the immunotherapy of cancer revealed that infusion of certain immunotherapeutic mAbs directed to tumor cells induced loss of targeted epitopes. This phenomenon, called antigenic modulation, can compromise m ... Full text Link to item Cite
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Education, Training & Certifications


Northwestern University · 2001 M.D.