David Adam Mack

Associate Professor of Medicine

Medicine, Medical Oncology

david.mack@duke.edu

2592 Morris Bldg, BOX_3395 Med Ctr, Durham, NC 27710

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Selected Publications

Binding of rituximab, trastuzumab, cetuximab, or mAb T101 to cancer cells promotes trogocytosis mediated by THP-1 cells and monocytes.

Journal Article J Immunol · December 1, 2008 More than 20 years ago clinical investigations in the immunotherapy of cancer revealed that infusion of certain immunotherapeutic mAbs directed to tumor cells induced loss of targeted epitopes. This phenomenon, called antigenic modulation, can compromise m ... Full text Link to item Cite