David Brett MacLeod
Assistant Professor of Anesthesiology

Clinical Anesthesia
My principal clinical interest is the use of peripheral nerve blocks in primarily orthopedic joint replacement procedures. I am a member of the Regional Division with responsibilities to spine, trauma & plastic surgery.


I was the co-director of the Carolina Cadaver Course, which was run annually in conjunction with Wake Forest University School of Medicine. I have been involved in teaching the use of ultrasound for the placement of peripheral nerve blocks and have lectured on several national courses.

Human Pharmacology & Physiology Lab (HPPL)
I am the Director of the HPPL which is the the Department of Anesthesiology's clinical research lab designed to conduct studies in healthy volunteers. It is designed to collect comprehensive physiological data in a manner similar to the Operating Room (OR), using both non-invasive and invasive techniques. The key areas of interest are:

  • Early human clinical drug trials (Phase 1 & 2) of drugs related to anesthesia
  • Conduct of clinical equipment validation studies prior to FDA approval

Current Appointments & Affiliations

Contact Information

  • 2301 Erwin Road, 5695 Hafs Building, Durham, NC 27708
  • Box 3094 Med Ctr, Durham, NC 27710

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