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David Severson

House Staff
Surgery

Current Appointments & Affiliations


Recent Publications


Abstract 95: Uncommitted cells and phenotypic plasticity elucidate the complexity of the epithelial-mesenchymal molecular gradient of pleural mesothelioma

Journal Article Cancer Research · April 4, 2023 AbstractPleural mesothelioma (PM) comprises three major histologic types: epithelioid, sarcomatoid, and a mixture of the two types termed biphasic. We and others have investigated whole transcriptome profile ... Full text Cite

Association of RERG Expression with Female Survival Advantage in Malignant Pleural Mesothelioma.

Journal Article Cancers · February 2021 Sex differences in incidence, prognosis, and treatment response have been described for many cancers. In malignant pleural mesothelioma (MPM), a lethal disease associated with asbestos exposure, men outnumber women 4 to 1, but women consistently live longe ... Full text Cite

Large-scale analysis of BAP1 expression reveals novel associations with clinical and molecular features of malignant pleural mesothelioma.

Journal Article The Journal of pathology · January 2021 BRCA1-associated protein-1 (BAP1) expression is commonly lost in several tumors including malignant pleural mesothelioma (MPM). Presence or absence of immunohistochemical BAP1 nuclear staining in tumor cells is currently used for differential diagnosis of ... Full text Cite
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Recent Grants


Decoding tumor-defining crosstalk between mesothelioma malignant cells and their microenvironment

FellowshipPI-Fellow · Awarded by American Cancer Society, Inc. · 2025 - 2026

Decoding tumor-defining crosstalk between mesothelioma malignant cells and their associated microenvironment

ResearchPI-Fellow · Awarded by American Association for Thoracic Surgery · 2024 - 2026

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