Scholars@Duke
Dewey G. McCafferty

Dewey G. McCafferty

Professor of Chemistry
Chemistry
dewey.mccafferty@duke.edu
Box 90346, B120 LSRC Bldg, Dept. Chemistry, Durham, NC 27708-0346
B120 LSRC, Box 90346, 450 Research Drive, Dept. Chemistry, Durham, NC 27708-0346

Selected Grants

Chemical Biology of the E3 Ubiqutin Ligase Nedd4

ResearchPrincipal Investigator · Awarded by National Institute of General Medical Sciences · 2023 - 2027

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Non-Opioid Post-Operative Pain Management Using Bupivicaine-loaded Poly(ester urea) Mesh

ResearchPrincipal Investigator · Awarded by 21MedTech, LLC · 2021 - 2023

Chemical Biology of Ubiquitin- and Neddylation-Protein Ligases in Neurodegeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2019 - 2022

Nedd4 E3 Ubiquitin Ligase as a Target for the Alleviation of Mutant Alpha-Synuclein Toxicity

ResearchPrincipal Investigator · Awarded by Michael J. Fox Foundation for Parkinson's Research · 2019 - 2020

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

Enzymology of Chlamydial Pathogenesis

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2020

Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer

EquipmentMajor User · Awarded by National Institutes of Health · 2018 - 2019

BC123577: Targeting Epigenetics Therapy for Estrogen Receptor Negative Breast Cancers

ResearchPrincipal Investigator · Awarded by United States Army Medical Research and Materiel Command · 2013 - 2016

Chemical Biology Approaches to Combat Parkinson's Disease and Dyskinesia

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2013 - 2016

Automated detection of protein crystals in high-throughput crystallography experiments

ResearchMajor User · Awarded by North Carolina Biotechnology Center · 2014 - 2015

Structural and Biochemical Studies of LpxC Inhibition

ResearchCollaborator · Awarded by National Institutes of Health · 2003 - 2014

Bioorganic Mechanisms of Chromatin Modifying Enzymes

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2011

Bioorganic Mechanisms of Peptide Antibiotics

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2011

Mechanistic Analyses of Protein Deacetylation

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2008

RSF: Properties and Dependence Upon Histone Modifications

FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2006 - 2007