Selected Grants
Targeting Hepatocyte Senescence to Improve NAFLD
ResearchMentor · Awarded by National Institutes of Health · 2024 - 2029The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program
ResearchPreceptor · Awarded by National Cancer Institute · 2023 - 2028Genomic Imprinting in the Development of NAFLD
ResearchSignificant Contributor · Awarded by National Institutes of Health · 2024 - 2028Therapeutic modulation of a proteomic HCC risk signature with statins in patients with liver cirrhosis
ResearchPrincipal Investigator · Awarded by University of Texas - Southwestern · 2023 - 2027Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)
ResearchCo Investigator · Awarded by National Institutes of Health · 2004 - 2027Duke Training Grant in Digestive Diseases and Nutrition
Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 1988 - 2027Building Interdisciplinary Research Careers in Women's Health - BIRCWH
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2002 - 2027Heterochronic hepatocyte transplantation to rejuvenate the aged liver
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2026Inventiva NATiV3
Clinical TrialPrincipal Investigator · Awarded by Inventiva · 2022 - 2025A multidisciplinary study of biological disparities in NASH progression and response to statins to inform personalized liver cancer chemoprevention in NAFLD
ResearchPrincipal Investigator · Awarded by Department of Defense · 2020 - 2025A Randomized Double-blind Placebo-controlled Phase 3 Study to Evaluate the Effect of Resmetirom on Liver-related Outcomes in Patients with Well-compensated (Child-Pugh A) Non-alcoholic Steato
Clinical TrialPrincipal Investigator · Awarded by Madrigal Pharmaceuticals, Inc. · 2023 - 2025The Imprinted Gene Network in the programming of non-alcoholic fatty liver disease by early life cadmium exposure
ResearchPrincipal Investigator · Awarded by North Carolina State University · 2020 - 2025Madrigal 3196-18 A 52-Week, Phase 3 Open-Label Extension Study, with a Resmetirom (MGL-3196) in Patients with Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension
Clinical TrialPrincipal Investigator · Awarded by Madrigal Pharmaceuticals, Inc. · 2023 - 2025Hepta Bio - Biorepository
ResearchPrincipal Investigator · Awarded by Hepta Bio, Inc. · 2023 - 2024Phase 1: Development of a Dual Chemokine CCL2/CCL5 Neutralizing Single-domain Antibody for Treating Non-alcoholic Steatoheptitis
ResearchPrincipal Investigator · Awarded by Oncotrap, Inc. · 2023 - 2024Hepatic Lipotoxicity, Metabolic Homeostasis and NAFLD Pathogenesis
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2023 - 2024Duke CTSA (TL1) Year 5
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2018 - 2024Hippo-Yap Pathway, Ferroptosis of Hepatic Stellate Cells and Liver Fibrosis
ResearchPrincipal Investigator · Awarded by American Association for the Study of Liver Diseases · 2021 - 2024TNF Alpha and Recovery from Alcoholic Liver Injury
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2014 - 2024Vitamin E Dosing Study (VEDS): A dose finding clinical trial of vitamin E for the treatment of adult NAFLD
Clinical TrialPrincipal Investigator · Awarded by Johns Hopkins University · 2022 - 2024Postdoctoral Training in Genomic Medicine Research
Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2017 - 2023Is Heart Failure with Preserved Edection Fraction the Symptomatic Manifestation of Liver Disease
ResearchCollaborator · Awarded by American Heart Association · 2021 - 2022Hedgehog Signaling and Adult Liver Regeneration
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2022Transmission electron microscope (TEM)
EquipmentMajor User · Awarded by National Institutes of Health · 2019 - 2021Pathophysiological Role of Glutaminolysis in Human NAFLD Progression
ResearchPrincipal Investigator · Awarded by American Association for the Study of Liver Diseases · 2018 - 2020TAIWANJ JKB 121-001
Clinical TrialPrincipal Investigator · Awarded by TaiwanJ Pharmaceuticals Co. Ltd · 2015 - 2020Genetic and Epigenetic Markers of Progressive Nonalcoholic Fatty Liver Disease
ResearchMentor · Awarded by American Association for the Study of Liver Diseases · 2018 - 2020Epigenetics and the Development of Nonalcoholic Fatty Liver Disease
ResearchMentor · Awarded by American College of Gastroenterology · 2015 - 2019Role of the Stroma in Fibrolamellar Hepatocellular Carcinoma
ResearchPrincipal Investigator · Awarded by Fibrolamellar Cancer Foundation · 2016 - 2019Submucosal esophageal structures as a progenitor niche for esophageal repair
ResearchMentor · Awarded by National Institutes of Health · 2013 - 2018Serial Block Face Scanning Electron Microscope
EquipmentMajor User · Awarded by National Institutes of Health · 2016 - 2018Impact of IMM-124E on Innate Immune and Fibrogenic Responses in Preclinical Mouse Model of NASH
ResearchPrincipal Investigator · Awarded by Immuron, Ltd · 2016 - 2018Impact of Fructose on Metabolism, Energy Homeostasis and MR biomarkers in NAFLD
ResearchCollaborator · Awarded by National Institutes of Health · 2012 - 2016Pathogenesis of NASH Cirrhosis
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2015 - 2016Cancer Biology Training Grant
Inst. Training Prgm or CMEMentor · Awarded by National Cancer Institute · 1993 - 2016Liver Disease in Obesity
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1999 - 2015TNF Alpha and Recovery from Alchoholic Liver Injury
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 1994 - 2014Rac1 Promotes Hepatic Stellate Accumulation/Activation in Liver Injury
ResearchMentor · Awarded by National Institutes of Health · 2009 - 2014Characterizing Alcohol's Effects on Repair of Liver Injury
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2012Hyperinsulimia and Insulin Resistance in Nonalcoholic Fatty Liver Disease
Clinical TrialMentor · Awarded by National Institutes of Health · 2006 - 2010Cholesterol, Hedgehog Signaling & Fetal Alcohol Syndrome
ResearchCo Investigator · Awarded by National Institutes of Health · 2007 - 2010Drug Abuse: Discovering Ligands for Pertinent GPCRs
ResearchCollaborator · Awarded by National Institutes of Health · 2006 - 2010Innovative Assays for Oncogenic Hedgehog Signaling
ResearchConsultant · Awarded by National Institutes of Health · 2006 - 2010Liver Derived Microparticles In Cirrhosis Pathogenesis
FellowshipPrincipal Investigator · Awarded by National Institutes of Health · 2008 - 2009Metabolic Profiling to Identify Alcohol Biomarker Signature
ResearchCo Investigator · Awarded by National Institutes of Health · 2006 - 2009Bioenergetics and Alcoholic Liver Disease Pathogenesis
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2000 - 2006External Relationships
- American Association for the Study of Liver Disease (AASLD)
- American Society of Toxicology
- Boehringer Ingleheim
- Federation of American Society for Experimental Biology
- Gordon Research Conferences
- International Society for Cells of Hepatic Sinusoid
- LA CATS (Lousiana CTSA)
- Louisiana State University Alcohol Research Center
- Midwest GI Society Annual Meeting
- NCI
- NIAAA
- Northern Ohio Alcohol Research Center
- Rockey Mountain GI Society Annual Meeting
- University of Iowa
- University of Louisville
- University of Pittsburgh
- Wallenberg Institute, University of Gottenberg, Gottenberg, Sweden
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.