Daniel P. Kiehart
Professor of Biology
Our intellectual focus is on identifying determinants of cell shape that function during development. Utilizing molecular genetic and reverse genetic approaches in Drosophila, we have shown that conventional nonmuscle myosin is necessary for driving both cell division and post-mitotic cell shape changes for morphogenesis. Currently, we are investigating how myosin elicits cell shape change and how its function is regulated through filament formation, phosphorylation, sub-cellular targeting, small GTP-binding proteins, kinase and phosphatase functions. In fly, we are using novel, near saturating screens to identify mutations that perturb dorsal closure, a model cell sheet movement that requires at least six different filamentous actin and/or actomyosin arrays for proper morphogenesis. Our screens show that nearly all aspects of closure a mutable -- by extrapolating our results, which have thus far screened approximately two-fifths of the fly genome, we project that the function of over 300 genes are required to drive this superficially simple, yet remarkably complex and sophisticated morphogenic process. We have also identified gene products that are necessary for myosin function by genetically recovering second site non-complementing loci and biochemically recovering proteins that bind to myosin. To date, our experiments identify ~30 loci that genetically interact with myosin and a kinase activity that phosphorylates myosin heavy chain and establish genetically, that the Rho signalling pathway is required in concert with nonmuscle myosin II for morphogenesis. Finally, we are using laser microsurgery and micro-manipulation studies to understand the forces that drive morphogenesis. We show that both the amnioserosa and the leading edge of the lateral epidermis contribute to the movements of dorsal closure. Finally, we are examining the role these proteins play in movements that occur during wound healing.
Office Hours
During Semesters (that I am not on leave) to be specified and by appointment arranged via email (dkiehart@duke.edu).
When school is not in session or during summer sessions, by appointment arranged via email (dkiehart@duke.edu).
When school is not in session or during summer sessions, by appointment arranged via email (dkiehart@duke.edu).
Current Appointments & Affiliations
- Professor of Biology, Biology, Trinity College of Arts & Sciences 2000
- Chief, Division of Developmental Biology, Cell Biology, Basic Science Departments 1993
- Professor of Cell Biology, Cell Biology, Basic Science Departments 2000
- Associate of the Duke Initiative for Science & Society, Duke Science & Society, Initiatives 2017
- Affiliate of the Duke Regeneration Center, Regeneration Next Initiative, Basic Science Departments 2021
Contact Information
- 4330 French Family Science Cen, Science Drive, Duke University, Durham, NC 27708-0338
- Box 90338, Dept. Biology, Duke University, Durham, NC 27708-1000
-
dkiehart@duke.edu
(919) 613-8157
-
http://www.biology.duke.edu/kiehartlab/
- Background
-
Education, Training, & Certifications
- Student, Summer Institute For Scientific Teaching, University of Wisconsin - Madison 2009
- Student, Physiology Course, Marine Biological Laboratory 1985
- Postdoctoral Fellow, Cell Biology And Anatomy, Johns Hopkins University 1978 - 1982
- Ph.D., University of Pennsylvania 1979
- B.A., University of Pennsylvania 1973
-
Previous Appointments & Affiliations
- Dean of the Natural Sciences, Trinity College of Arts & Sciences, Duke University 2013 - 2019
- Faculty Network Member of The Energy Initiative, Nicholas Institute-Energy Initiative, Initiatives 2015
- Chair of the Department of Biology, Biology, Trinity College of Arts & Sciences 2007 - 2013
- Associate Professor of Cell Biology, Cell Biology, Basic Science Departments 1992 - 2000
- Director, University Program in Genetics, Cell Biology, Basic Science Departments 1997 - 2000
-
Leadership & Clinical Positions at Duke
-
2013-2019 Dean of Natural Sciences, Trinity College of Arts and Sciences
2007-2013 Chair, Department of Biology, Trinity College of Arts and Sciences
1997-2001 Director, University Program in Genetics
1992-2000 Chief, Division of Developmental Biology, Dept. of Cell Biol. Duke Univ. Med. Ctr.
-
-
Academic Positions Outside Duke
- Associate Professor, Department of Cellular and Developmental Biology, Harvard University. 1988 - 1992
- Assistant Professor, Department of Cellular and Developmental Biology, Harvard University. 1984 - 1988
- Research Associate (Research Faculty), Johns Hopkins School of Medicine. 1982 - 1984
- Recognition
-
In the News
-
JUL 6, 2022 Duke Research Blog -
APR 21, 2016 -
FEB 21, 2016 Duke Today -
NOV 13, 2014 Duke Research Blog -
SEP 10, 2014 -
JUL 15, 2014 Duke Today -
JUL 9, 2014 Duke Today
-
-
Awards & Honors
- Fellow (Inaugural Class), American Society for Cell Biology. American Society for Cell Biology. 2015
- Newcomb Cleveland Award for the Outstanding Paper in Science. American Association for the Advancement of Science. 2015
- Elected Fellow of the American Association for the Advancement of Science. American Association for the Advancement of Science Council. November 2011
- Sigma Xi Award for the Best Dissertation at the Unversity of Pennsylvania (1979). Sigma Xi, University of Pennsylvania. 1979
- Expertise
-
Subject Headings
- Actin Cytoskeleton
- Actomyosin
- Adhesion
- Biophysics
- Cell Adhesion
- Cell Adhesion Molecules
- Cell adhesion--Molecular aspects
- Drosophila melanogaster
- Drosophila--Genetics
- Molecular Biology
- Morphogenesis
- Morphogenesis--Molecular aspects
- Myosin
- Myosin Heavy Chains
- Myosin Light Chains
- Myosin Subfragments
- Myosin antibodies
- Myosin-Light-Chain Kinase
- Myosin-Light-Chain Phosphatase
- Myosins
- Research
-
Selected Grants
- Training Program in Developmental and Stem Cell Biology awarded by National Institutes of Health 2001 - 2027
- Cell and Molecular Biology Training Program awarded by National Institutes of Health 2021 - 2026
- Genetic and Genomics Training Grant awarded by National Institutes of Health 2020 - 2025
- LUMICKS C-TRAP awarded by National Institutes of Health 2022 - 2023
- Morphogenesis: Biophysics and Genetics of Dorsal Closure awarded by National Institutes of Health 2018 - 2023
- Faculty Springboard to Advance Breakthrough Science by Post-Tenure Faculty awarded by National Science Foundation 2018 - 2021
- Super-resolution Imaging via Multiple Modalities with the Zeiss Elyra 7 awarded by National Institutes of Health 2020 - 2021
- Genetics Training Grant awarded by National Institutes of Health 1979 - 2020
- Organization and Function of Cellular Structure awarded by National Institutes of Health 1975 - 2020
- Morphogenesis: Biophysics and Genetics of Dorsal Closure awarded by National Institutes of Health 1984 - 2018
- Lightsheet Imaging System awarded by National Institutes of Health 2016 - 2017
- Structural Biology and Biophysics Training Program awarded by National Institutes of Health 1994 - 2015
- Institutional Training Grant in Pediatric Cardiology awarded by National Institutes of Health 2009 - 2015
- Design and Implementation of Genetically Encoded Myosin Based Force Sensors awarded by National Institutes of Health 2012 - 2015
- New Console and Cold Probe for the Duke 600 MHz NMR Spectrometer System awarded by National Institutes of Health 2013 - 2014
- Non Muscle Myosin II Contractility Putatively Regulates Scar Contracture awarded by National Institutes of Health 2008 - 2013
- Actin Protrusions, Oocytes: Myosin VIIA and the Actin Cytoskeleton awarded by National Institutes of Health 2010 - 2013
- Replacement Equipment Components for an 800 MHz NMR Spectrometer awarded by National Institutes of Health 2010 - 2011
- Myosins VIIA, VIIB & XV in Fly Hearing and Morphogenesis awarded by National Institutes of Health 2005 - 2011
- Integrated instrument systems for maintenance and delivery of RNAi libraries awarded by National Institutes of Health 2008 - 2009
- Duke PREP: Minority Recruitment into Biomedical Sciences awarded by National Institutes of Health 2003 - 2008
- Molecular Genetic Analysis of Wound Healing in Drosophila awarded by National Institutes of Health 2000 - 2004
- Cytoplasmic Myosin Function in Vivo and in Vitro awarded by National Institutes of Health 1984 - 2004
- Center for FEL Research in the Medical, Biological, and Materials Sciences awarded by Air Force Office of Scientific Research 2000 - 2001
- Real Time Analysis Of Wounding And Healing By Two Photon M awarded by Office of Naval Research 1997 - 2000
- Cytoplasmic Myosin Function In Vitro awarded by National Institutes of Health 1996 - 1999
- Genetics Training Grant awarded by National Institutes of Health 1997 - 1999
- Dynamic Cytoskeletal Function Of A Myosin In Development awarded by National Institutes of Health 1995 - 1998
- Cytoplasmic Myosin Function In Vitro And In Vivo awarded by National Institutes of Health 1995 - 1996
- Publications & Artistic Works
-
Selected Publications
-
Academic Articles
-
Allen, Raymond L., Andrew N. George, Esther Miranda, Taji M. Phillips, Janice M. Crawford, Daniel P. Kiehart, and David R. McClay. “Wound repair in sea urchin larvae involves pigment cells and blastocoelar cells.” Developmental Biology 491 (November 2022): 56–65. https://doi.org/10.1016/j.ydbio.2022.08.005.Full Text
-
Haertter, Daniel, Xiaolei Wang, Stephanie M. Fogerson, Nitya Ramkumar, Janice M. Crawford, Kenneth D. Poss, Stefano Di Talia, Daniel P. Kiehart, and Christoph F. Schmidt. “DeepProjection: specific and robust projection of curved 2D tissue sheets from 3D microscopy using deep learning.” Development 149, no. 21 (November 1, 2022). https://doi.org/10.1242/dev.200621.Full Text Link to Item
-
Moore, Regan P., Stephanie M. Fogerson, U Serdar Tulu, Jason W. Yu, Amanda H. Cox, Melissa A. Sican, Dong Li, et al. “Superresolution microscopy reveals actomyosin dynamics in medioapical arrays.” Molecular Biology of the Cell 33, no. 11 (September 2022): ar94. https://doi.org/10.1091/mbc.e21-11-0537.Full Text
-
Sallee, Jennifer L., Janice M. Crawford, Vinay Singh, and Daniel P. Kiehart. “Mutations in Drosophila crinkled/Myosin VIIA disrupt denticle morphogenesis.” Developmental Biology 470 (February 2021): 121–35. https://doi.org/10.1016/j.ydbio.2020.11.007.Full Text
-
Fogerson, Stephanie M., Richard D. Mortensen, Regan P. Moore, Hellen Y. Chiou, Neel K. Prabhu, Angela H. Wei, Daniel Tsai, et al. “Identifying Key Genetic Regions for Cell Sheet Morphogenesis on Chromosome 2L Using a Drosophila Deficiency Screen in Dorsal Closure.” G3 (Bethesda, Md.) 10, no. 11 (November 2020): 4249–69. https://doi.org/10.1534/g3.120.401386.Full Text
-
Kiehart, Daniel P., and John A. Cooper. “Contractile protein biochemistry in the Pollard Lab in Baltimore.” Biophysical Reviews 10, no. 6 (December 2018): 1483–85. https://doi.org/10.1007/s12551-018-0477-5.Full Text
-
Guo, Yuting, Di Li, Siwei Zhang, Yanrui Yang, Jia-Jia Liu, Xinyu Wang, Chong Liu, et al. “Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales.” Cell 175, no. 5 (November 2018): 1430-1442.e17. https://doi.org/10.1016/j.cell.2018.09.057.Full Text
-
Aristotelous, A. C., J. M. Crawford, G. S. Edwards, D. P. Kiehart, and S. Venakides. “Mathematical models of dorsal closure.” Progress in Biophysics and Molecular Biology 137 (September 2018): 111–31. https://doi.org/10.1016/j.pbiomolbio.2018.05.009.Full Text
-
Mortensen, Richard D., Regan P. Moore, Stephanie M. Fogerson, Hellen Y. Chiou, Chimdindu V. Obinero, Neel K. Prabhu, Angela H. Wei, Janice M. Crawford, and Daniel P. Kiehart. “Identifying Genetic Players in Cell Sheet Morphogenesis Using a Drosophila Deficiency Screen for Genes on Chromosome 2R Involved in Dorsal Closure.” G3 (Bethesda, Md.) 8, no. 7 (July 2018): 2361–87. https://doi.org/10.1534/g3.118.200233.Full Text
-
Lo, Wei-Chang, Craig Madrak, Daniel P. Kiehart, and Glenn S. Edwards. “Unified biophysical mechanism for cell-shape oscillations and cell ingression.” Physical Review. E 97, no. 6–1 (June 2018): 062414. https://doi.org/10.1103/physreve.97.062414.Full Text
-
Kiehart, Daniel P., Janice M. Crawford, Andreas Aristotelous, Stephanos Venakides, and Glenn S. Edwards. “Cell Sheet Morphogenesis: Dorsal Closure in Drosophila melanogaster as a Model System.” Annual Review of Cell and Developmental Biology 33 (October 2017): 169–202. https://doi.org/10.1146/annurev-cellbio-111315-125357.Full Text
-
Cao, Jingli, Jinhu Wang, Christopher P. Jackman, Amanda H. Cox, Michael A. Trembley, Joseph J. Balowski, Ben D. Cox, et al. “Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue.” Dev Cell 42, no. 6 (September 25, 2017): 600-615.e4. https://doi.org/10.1016/j.devcel.2017.08.024.Full Text Link to Item
-
Lu, Heng, Adam Sokolow, Daniel P. Kiehart, and Glenn S. Edwards. “Quantifying dorsal closure in three dimensions.” Molecular Biology of the Cell 27, no. 25 (December 2016): 3948–55. https://doi.org/10.1091/mbc.e16-06-0400.Full Text
-
Marston, Daniel J., Christopher D. Higgins, Kimberly A. Peters, Timothy D. Cupp, Daniel J. Dickinson, Ariel M. Pani, Regan P. Moore, Amanda H. Cox, Daniel P. Kiehart, and Bob Goldstein. “MRCK-1 Drives Apical Constriction in C. elegans by Linking Developmental Patterning to Force Generation.” Current Biology : Cb 26, no. 16 (August 2016): 2079–89. https://doi.org/10.1016/j.cub.2016.06.010.Full Text
-
Lu, Heng, Adam Sokolow, Daniel P. Kiehart, and Glenn S. Edwards. “Remodeling Tissue Interfaces and the Thermodynamics of Zipping during Dorsal Closure in Drosophila.” Biophysical Journal 109, no. 11 (December 2015): 2406–17. https://doi.org/10.1016/j.bpj.2015.10.017.Full Text
-
Goldstein, Bob, and Daniel P. Kiehart. “Moving Inward: Establishing the Mammalian Inner Cell Mass.” Developmental Cell 34, no. 4 (August 2015): 385–86. https://doi.org/10.1016/j.devcel.2015.08.007.Full Text
-
Kiehart, Daniel P. “Epithelial morphogenesis: apoptotic forces drive cell shape changes.” Developmental Cell 32, no. 5 (March 2015): 532–33. https://doi.org/10.1016/j.devcel.2015.02.020.Full Text
-
Wells, Adrienne R., Roger S. Zou, U Serdar Tulu, Adam C. Sokolow, Janice M. Crawford, Glenn S. Edwards, and Daniel P. Kiehart. “Complete canthi removal reveals that forces from the amnioserosa alone are sufficient to drive dorsal closure in Drosophila.” Molecular Biology of the Cell 25, no. 22 (November 2014): 3552–68. https://doi.org/10.1091/mbc.e14-07-1190.Full Text
-
Chen, Bi-Chang, Wesley R. Legant, Kai Wang, Lin Shao, Daniel E. Milkie, Michael W. Davidson, Chris Janetopoulos, et al. “Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution.” Science (New York, N.Y.) 346, no. 6208 (October 2014): 1257998. https://doi.org/10.1126/science.1257998.Full Text
-
Hunter, Ginger L., Janice M. Crawford, Julian Z. Genkins, and Daniel P. Kiehart. “Ion channels contribute to the regulation of cell sheet forces during Drosophila dorsal closure.” Development (Cambridge, England) 141, no. 2 (January 2014): 325–34. https://doi.org/10.1242/dev.097097.Full Text
-
Tulu, U. S., M. C. Beckerle, and D. P. Kiehart. “Cell Junctions and the Tension Sensitive, Supracellular Purse Strings in Drosophila Dorsal Closure (Submitted).” J. Cell Biol., June 2012.
-
Hunter, G., J. Crawford, J. Genkins, and D. P. Kiehart. “Ion channels function in the mechanoregulation of cell sheet forces during Drosophila morphogenesis (Submitted).” Developmental Cell, May 2012.
-
Roh-Johnson, Minna, Gidi Shemer, Christopher D. Higgins, Joseph H. McClellan, Adam D. Werts, U Serdar Tulu, Liang Gao, Eric Betzig, Daniel P. Kiehart, and Bob Goldstein. “Triggering a cell shape change by exploiting preexisting actomyosin contractions.” Science (New York, N.Y.) 335, no. 6073 (March 2012): 1232–35. https://doi.org/10.1126/science.1217869.Full Text
-
Sokolow, Adam, Yusuke Toyama, Daniel P. Kiehart, and Glenn S. Edwards. “Cell ingression and apical shape oscillations during dorsal closure in Drosophila.” Biophysical Journal 102, no. 5 (March 2012): 969–79. https://doi.org/10.1016/j.bpj.2012.01.027.Full Text
-
Boyle, M. J., R. L. French, K. A. Cosand, J. B. Dorman, D. P. Kiehart, and C. A. Berg. “Division of labor: subsets of dorsal-appendage-forming cells control the shape of the entire tube.” Developmental Biology 346, no. 1 (October 2010): 68–79. https://doi.org/10.1016/j.ydbio.2010.07.018.Full Text
-
Franke, Josef D., Ruth A. Montague, and Daniel P. Kiehart. “Nonmuscle myosin II is required for cell proliferation, cell sheet adhesion and wing hair morphology during wing morphogenesis.” Developmental Biology 345, no. 2 (September 2010): 117–32. https://doi.org/10.1016/j.ydbio.2010.06.028.Full Text
-
Layton, Anita T., Yusuke Toyama, Guo-Qiang Yang, Glenn S. Edwards, Daniel P. Kiehart, and Stephanos Venakides. “Drosophila morphogenesis: tissue force laws and the modeling of dorsal closure.” Hfsp Journal 3, no. 6 (December 2009): 441–60. https://doi.org/10.2976/1.3266062.Full Text
-
Toyama, Yusuke, Xomalin G. Peralta, Adrienne R. Wells, Daniel P. Kiehart, and Glenn S. Edwards. “Apoptotic force and tissue dynamics during Drosophila embryogenesis.” Science (New York, N.Y.) 321, no. 5896 (September 2008): 1683–86. https://doi.org/10.1126/science.1157052.Full Text
-
Rodriguez-Diaz, Alice, Yusuke Toyama, Daniel L. Abravanel, John M. Wiemann, Adrienne R. Wells, U Serdar Tulu, Glenn S. Edwards, and Daniel P. Kiehart. “Actomyosin purse strings: renewable resources that make morphogenesis robust and resilient.” Hfsp Journal 2, no. 4 (August 2008): 220–37. https://doi.org/10.2976/1.2955565.Full Text
-
Todi, Sokol V., Elena Sivan-Loukianova, Julie S. Jacobs, Daniel P. Kiehart, and Daniel F. Eberl. “Myosin VIIA, important for human auditory function, is necessary for Drosophila auditory organ development.” Plos One 3, no. 5 (May 2008): e2115. https://doi.org/10.1371/journal.pone.0002115.Full Text Open Access Copy
-
Peralta, X. G., Y. Toyama, D. P. Kiehart, and G. S. Edwards. “Emergent properties during dorsal closure in Drosophila morphogenesis.” Physical Biology 5, no. 1 (April 2008): 015004. https://doi.org/10.1088/1478-3975/5/1/015004.Full Text
-
Peralta, X. G., Y. Toyama, D. P. Kiehart, and G. S. Edwards. “Emergent properties during dorsal closure in Drosophila morphogenesis.” Physical Biology 5, no. 1 (2008): 15004.
-
Franke, Josef D., Ruth A. Montague, Wayne L. Rickoll, and Daniel P. Kiehart. “An MYH9 human disease model in flies: site-directed mutagenesis of the Drosophila non-muscle myosin II results in hypomorphic alleles with dominant character.” Human Molecular Genetics 16, no. 24 (December 2007): 3160–73. https://doi.org/10.1093/hmg/ddm279.Full Text
-
Peralta, X. G., Y. Toyama, M. S. Hutson, R. Montague, S. Venakides, D. P. Kiehart, and G. S. Edwards. “Upregulation of forces and morphogenic asymmetries in dorsal closure during Drosophila development.” Biophysical Journal 92, no. 7 (April 2007): 2583–96. https://doi.org/10.1529/biophysj.106.094110.Full Text
-
Kiehart, D. P., and K. Bloom. “Cell structure and dynamics.” Current Opinion in Cell Biology 19, no. 1 (February 1, 2007): 1–4. https://doi.org/10.1016/j.ceb.2006.12.015.Full Text
-
Kiehart, D. P., Y. Tokutake, M. S. Chang, M. S. Hutson, J. Wiemann, X. G. Peralta, Y. Toyama, A. R. Wells, A. Rodriguez, and G. S. Edwards. “Ultraviolet Laser Microbeam for Dissection of Drosophila Embryos” 3 (December 1, 2006): 87–103. https://doi.org/10.1016/B978-012164730-8/50137-4.Full Text
-
Franke, Josef D., Amanda L. Boury, Noel J. Gerald, and Daniel P. Kiehart. “Native nonmuscle myosin II stability and light chain binding in Drosophila melanogaster.” Cell Motility and the Cytoskeleton 63, no. 10 (October 2006): 604–22. https://doi.org/10.1002/cm.20148.Full Text
-
Yang, Yi, Mihály Kovács, Takeshi Sakamoto, Fang Zhang, Daniel P. Kiehart, and James R. Sellers. “Dimerized Drosophila myosin VIIa: a processive motor.” Proceedings of the National Academy of Sciences of the United States of America 103, no. 15 (April 2006): 5746–51. https://doi.org/10.1073/pnas.0509935103.Full Text
-
Homsy, Jason G., Heinrich Jasper, Xomalin G. Peralta, Hai Wu, Daniel P. Kiehart, and Dirk Bohmann. “JNK signaling coordinates integrin and actin functions during Drosophila embryogenesis.” Developmental Dynamics : An Official Publication of the American Association of Anatomists 235, no. 2 (February 2006): 427–34. https://doi.org/10.1002/dvdy.20649.Full Text
-
Franke, Josef D., Ruth A. Montague, and Daniel P. Kiehart. “Nonmuscle myosin II generates forces that transmit tension and drive contraction in multiple tissues during dorsal closure.” Current Biology : Cb 15, no. 24 (December 2005): 2208–21. https://doi.org/10.1016/j.cub.2005.11.064.Full Text
-
Todi, Sokol V., Josef D. Franke, Daniel P. Kiehart, and Daniel F. Eberl. “Myosin VIIA defects, which underlie the Usher 1B syndrome in humans, lead to deafness in Drosophila.” Current Biology : Cb 15, no. 9 (May 2005): 862–68. https://doi.org/10.1016/j.cub.2005.03.050.Full Text
-
Franke, Josef D., Fan Dong, Wayne L. Rickoll, Michael J. Kelley, and Daniel P. Kiehart. “Rod mutations associated with MYH9-related disorders disrupt nonmuscle myosin-IIA assembly.” Blood 105, no. 1 (January 1, 2005): 161–69. https://doi.org/10.1182/blood-2004-06-2067.Full Text Link to Item
-
Kiehart, Daniel P., Josef D. Franke, Mark K. Chee, R. A. Montague, Tung-Ling Chen, John Roote, and Michael Ashburner. “Drosophila crinkled, mutations of which disrupt morphogenesis and cause lethality, encodes fly myosin VIIA.” Genetics 168, no. 3 (November 2004): 1337–52. https://doi.org/10.1534/genetics.104.026369.Full Text
-
Dorman, J. B., K. E. James, S. E. Fraser, D. P. Kiehart, and C. A. Berg. “bullwinkle is required for epithelial morphogenesis during Drosophila oogenesis.” Developmental Biology, Usa 267, no. 2 (March 2004): 320–41.Link to Item
-
Kiehart, Daniel P. “Myosins motor Miranda.” Molecular Cell 12, no. 6 (December 2003): 1346–47. https://doi.org/10.1016/s1097-2765(03)00495-7.Full Text
-
Bayer, Cynthia A., Susan R. Halsell, James W. Fristrom, Daniel P. Kiehart, and Laurence von Kalm. “Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis.” Genetics 165, no. 3 (November 2003): 1417–32. https://doi.org/10.1093/genetics/165.3.1417.Full Text
-
Edwards, G. S., R. H. Austin, F. E. Carroll, M. L. Copeland, M. E. Couprie, W. E. Gabella, R. F. Huglund, et al. “Free-electron-laser-based biophysical and biomedical instrumentation.” Review of Scientific Instruments 74, no. 7 (July 1, 2003): 3207–45. https://doi.org/10.1063/1.1584078.Full Text
-
Hutson, M Shane, Yoichiro Tokutake, Ming-Shien Chang, James W. Bloor, Stephanos Venakides, Daniel P. Kiehart, and Glenn S. Edwards. “Forces for morphogenesis investigated with laser microsurgery and quantitative modeling.” Science (New York, N.Y.) 300, no. 5616 (April 2003): 145–49. https://doi.org/10.1126/science.1079552.Full Text
-
Edwards, G. S., R. H. Austin, F. E. Carroll, M. L. Copeland, M. E. Couprie, W. E. Gabella, R. F. Haglund, et al. “FEL-based biophysical and biomedical instrumentation.” Invited Paper, Review of Scientific Instruments 74, no. 7 (2003): 3207–45.
-
Dutta, Devkanya, James W. Bloor, Mar Ruiz-Gomez, K. VijayRaghavan, and Daniel P. Kiehart. “Real-time imaging of morphogenetic movements in Drosophila using Gal4-UAS-driven expression of GFP fused to the actin-binding domain of moesin.” Genesis (New York, N.Y. : 2000) 34, no. 1–2 (September 2002): 146–51. https://doi.org/10.1002/gene.10113.Full Text
-
Kiehart, Daniel P., and Josef D. Franke. “Actin dynamics: the arp2/3 complex branches out.” Current Biology : Cb 12, no. 16 (August 2002): R557–59. https://doi.org/10.1016/s0960-9822(02)01053-9.Full Text
-
Bloor, James W., and Daniel P. Kiehart. “Drosophila RhoA regulates the cytoskeleton and cell-cell adhesion in the developing epidermis.” Development (Cambridge, England) 129, no. 13 (July 2002): 3173–83. https://doi.org/10.1242/dev.129.13.3173.Full Text
-
Ohashi, Tomoo, Daniel P. Kiehart, and Harold P. Erickson. “Dual labeling of the fibronectin matrix and actin cytoskeleton with green fluorescent protein variants.” J Cell Sci 115, no. Pt 6 (March 15, 2002): 1221–29. https://doi.org/10.1242/jcs.115.6.1221.Full Text Link to Item
-
Bloor, J. W., and D. P. Kiehart. “zipper Nonmuscle myosin-II functions downstream of PS2 integrin in Drosophila myogenesis and is necessary for myofibril formation.” Developmental Biology 239, no. 2 (November 2001): 215–28. https://doi.org/10.1006/dbio.2001.0452.Full Text
-
Su, Z., and D. P. Kiehart. “Protein kinase C phosphorylates nonmuscle myosin-II heavy chain from Drosophila but regulation of myosin function by this enzyme is not required for viability in flies.” Biochemistry 40, no. 12 (March 2001): 3606–14. https://doi.org/10.1021/bi010082j.Full Text
-
Crawford, J. M., Z. Su, O. Varlamova, A. R. Bresnick, and D. P. Kiehart. “Role of myosin-II phosphorylation in V12Cdc42-mediated disruption of Drosophila cellularization.” European Journal of Cell Biology 80, no. 3 (March 2001): 240–44.
-
Champagne, M. B., K. A. Edwards, H. P. Erickson, and D. P. Kiehart. “Drosophila stretchin-MLCK is a novel member of the Titin/Myosin light chain kinase family.” J Mol Biol 300, no. 4 (July 21, 2000): 759–77. https://doi.org/10.1006/jmbi.2000.3802.Full Text Link to Item
-
Halsell, S. R., B. I. Chu, and D. P. Kiehart. “Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during Drosophila morphogenesis.” Genetics 155, no. 3 (July 2000): 1253–65. https://doi.org/10.1093/genetics/155.3.1253.Full Text
-
Kiehart, D. P., C. G. Galbraith, K. A. Edwards, W. L. Rickoll, and R. A. Montague. “Multiple forces contribute to cell sheet morphogenesis for dorsal closure in Drosophila.” The Journal of Cell Biology 149, no. 2 (April 2000): 471–90. https://doi.org/10.1083/jcb.149.2.471.Full Text
-
Halsell, S. R., B. I. Chu, and D. P. Kiehart. “Erratum: Genetic analysis demonstrates a direct link between rho signaling and nonmuscle myosin function during drosophila morphogenesis (Genetics 155 (1253-1265)).” Genetics 156, no. 1 (January 1, 2000): 469.
-
Kiehart, D. P. “Wound healing: The power of the purse string.” Current Biology : Cb 9, no. 16 (August 1999): R602–5. https://doi.org/10.1016/s0960-9822(99)80384-4.Full Text
-
Crawford, J. M., and D. P. Kiehart. “Biology in pictures: From one cell to many.” Current Biology : Cb 9, no. 11 (June 1999): R389.
-
Ohashi, T., D. P. Kiehart, and H. P. Erickson. “Dynamics and elasticity of the fibronectin matrix in living cell culture visualized by fibronectin-green fluorescent protein.” Proc Natl Acad Sci U S A 96, no. 5 (March 2, 1999): 2153–58. https://doi.org/10.1073/pnas.96.5.2153.Full Text Link to Item
-
Crawford, J. M., N. Harden, T. Leung, L. Lim, and D. P. Kiehart. “Cellularization in Drosophila melanogaster is disrupted by the inhibition of rho activity and the activation of Cdc42 function.” Developmental Biology, Usa 204, no. 1 (December 1998): 151–64.
-
Aitken, P. G., A. J. Borgdorff, A. J. Juta, D. P. Kiehart, G. G. Somjen, and W. J. Wadman. “Volume changes induced by osmotic stress in freshly isolated rat hippocampal neurons.” Pflugers Arch 436, no. 6 (November 1998): 991–98. https://doi.org/10.1007/s004240050734.Full Text Link to Item
-
Thomas, G. H., D. C. Zarnescu, A. E. Juedes, M. A. Bales, A. Londergan, C. C. Korte, and D. P. Kiehart. “Drosophila betaHeavy-spectrin is essential for development and contributes to specific cell fates in the eye.” Development (Cambridge, England) 125, no. 11 (June 1998): 2125–34. https://doi.org/10.1242/dev.125.11.2125.Full Text
-
Halsell, S. R., and D. P. Kiehart. “Second-site noncomplementation identifies genomic regions required for Drosophila nonmuscle myosin function during morphogenesis.” Genetics 148, no. 4 (April 1998): 1845–63. https://doi.org/10.1093/genetics/148.4.1845.Full Text
-
Thomas, G. H., E. C. Newbern, C. C. Korte, M. A. Bales, S. V. Muse, A. G. Clark, and D. P. Kiehart. “Intragenic duplication and divergence in the spectrin superfamily of proteins.” Molecular Biology and Evolution, Usa 14, no. 12 (December 1997): 1285–95.
-
Edwards, K. A., M. Demsky, R. A. Montague, N. Weymouth, and D. P. Kiehart. “GFP-moesin illuminates actin cytoskeleton dynamics in living tissue and demonstrates cell shape changes during morphogenesis in Drosophila.” Developmental Biology 191, no. 1 (November 1997): 103–17. https://doi.org/10.1006/dbio.1997.8707.Full Text
-
Pederson, J. D., D. P. Kiehart, and J. W. Mahaffey. “The role of HOM-C genes in segmental transformations: reexamination of the Drosophila Sex combs reduced embryonic phenotype.” Developmental Biology 180, no. 1 (November 1996): 131–42. https://doi.org/10.1006/dbio.1996.0290.Full Text
-
Cooper, J. A., and D. P. Kiehart. “Septins may form a ubiquitous family of cytoskeletal filaments.” The Journal of Cell Biology 134, no. 6 (September 1996): 1345–48. https://doi.org/10.1083/jcb.134.6.1345.Full Text
-
Edwards, K. A., and D. P. Kiehart. “Drosophila nonmuscle myosin II has multiple essential roles in imaginal disc and egg chamber morphogenesis.” Development (Cambridge, England) 122, no. 5 (May 1996): 1499–1511. https://doi.org/10.1242/dev.122.5.1499.Full Text
-
Mansfield, S. G., D. Y. al-Shirawi, A. S. Ketchum, E. C. Newbern, and D. P. Kiehart. “Molecular organization and alternative splicing in zipper, the gene that encodes the Drosophila non-muscle myosin II heavy chain.” Journal of Molecular Biology 255, no. 1 (January 1996): 98–109. https://doi.org/10.1006/jmbi.1996.0009.Full Text
-
Edwards, K. A., X. J. Chang, and D. P. Kiehart. “Essential light chain of Drosophila nonmuscle myosin II.” Journal of Muscle Research and Cell Motility 16, no. 5 (October 1995): 491–98. https://doi.org/10.1007/bf00126433.Full Text
-
Miller, K. G., and D. P. Kiehart. “Fly division.” The Journal of Cell Biology 131, no. 1 (October 1995): 1–5. https://doi.org/10.1083/jcb.131.1.1.Full Text
-
Thomas, G. H., and D. P. Kiehart. “Beta heavy-spectrin has a restricted tissue and subcellular distribution during Drosophila embryogenesis.” Development (Cambridge, England) 120, no. 7 (July 1994): 2039–50. https://doi.org/10.1242/dev.120.7.2039.Full Text
-
Edwards, K. A., R. A. Montague, S. Shepard, B. A. Edgar, R. L. Erikson, and D. P. Kiehart. “Identification of Drosophila cytoskeletal proteins by induction of abnormal cell shape in fission yeast.” Proceedings of the National Academy of Sciences of the United States of America 91, no. 10 (May 1994): 4589–93. https://doi.org/10.1073/pnas.91.10.4589.Full Text
-
Kiehart, D. P., R. A. Montague, W. L. Rickoll, D. Foard, and G. H. Thomas. “High-resolution microscopic methods for the analysis of cellular movements in Drosophila embryos.” Methods in Cell Biology 44 (January 1994): 507–32. https://doi.org/10.1016/s0091-679x(08)60929-2.Full Text
-
Thomas, G. H., and D. P. Kiehart. “β(Heavy)spectrin has a restricted tissue and subcellular distribution during Drosophila embryogenesis.” Development 120, no. 7 (January 1, 1994): 2039–50.
-
Kiehart, D. P., R. A. Montague, W. L. Rickoll, D. Foard, and G. H. Thomas. “High-resolution microscopic methods for the analysis of cellular movements in Drosophila embryos.” Methods in Cell Biology 44 (1994): 507–32.
-
Thomas, G. H., and D. P. Kiehart. “βHavy-spectrin has a restricted tissue and subcellular distribution during Drosophila embryogenesis.” Development 120, no. 7 (1994): 2039–50.
-
Young, P. E., A. M. Richman, A. S. Ketchum, and D. P. Kiehart. “Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function.” Genes & Development 7, no. 1 (January 1993): 29–41. https://doi.org/10.1101/gad.7.1.29.Full Text
-
Karess, R. E., X. J. Chang, K. A. Edwards, S. Kulkarni, I. Aguilera, and D. P. Kiehart. “The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila.” Cell 65, no. 7 (June 1991): 1177–89. https://doi.org/10.1016/0092-8674(91)90013-o.Full Text
-
Kiehart, D. P. “Chapter 6 Contractile and Cytoskeletal Proteins in Drosophila Embryogenesis.” Current Topics in Membranes 38, no. C (January 1, 1991): 79–97. https://doi.org/10.1016/S0070-2161(08)60783-2.Full Text
-
Young, P. E., T. C. Pesacreta, and D. P. Kiehart. “Dynamic changes in the distribution of cytoplasmic myosin during Drosophila embryogenesis.” Development (Cambridge, England) 111, no. 1 (January 1991): 1–14. https://doi.org/10.1242/dev.111.1.1.Full Text
-
Rimm, D. L., D. A. Kaiser, D. Bhandari, P. Maupin, D. P. Kiehart, and T. D. Pollard. “Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites.” The Journal of Cell Biology 111, no. 6 Pt 1 (December 1990): 2405–16. https://doi.org/10.1083/jcb.111.6.2405.Full Text
-
Rimm, D. L., D. A. Kaiser, D. Bhandari, P. Maupin, D. P. Kiehart, and T. D. Pollard. “Identification of functional regions on the tail of Acanthamoeba myosin-II using recombinant fusion proteins. I. High resolution epitope mapping and characterization of monoclonal antibody binding sites.” Journal of Cell Biology 111, no. 6 I (December 1, 1990): 2405–16. https://doi.org/10.1083/jcb.111.6.2405.Full Text
-
Dubreuil, R. R., T. J. Byers, C. T. Stewart, and D. P. Kiehart. “A beta-spectrin isoform from Drosophila (beta H) is similar in size to vertebrate dystrophin.” The Journal of Cell Biology 111, no. 5 Pt 1 (November 1990): 1849–58. https://doi.org/10.1083/jcb.111.5.1849.Full Text
-
Kiehart, D. P. “The actin membrane skeleton in Drosophila development.” Seminars in Cell Biology 1, no. 5 (October 1990): 325–39.
-
Ketchum, A. S., C. T. Stewart, M. Stewart, and D. P. Kiehart. “Complete sequence of the Drosophila nonmuscle myosin heavy-chain transcript: conserved sequences in the myosin tail and differential splicing in the 5' untranslated sequence.” Proceedings of the National Academy of Sciences of the United States of America 87, no. 16 (August 1990): 6316–20. https://doi.org/10.1073/pnas.87.16.6316.Full Text
-
Kiehart, D. P. “Molecular genetic dissection of myosin heavy chain function.” Cell 60, no. 3 (February 1990): 347–50. https://doi.org/10.1016/0092-8674(90)90583-z.Full Text
-
Dubreuil, R. R., T. J. Byers, C. T. Stewart, and D. P. Kiehart. “A β-spectrin isoform from Drosophila (βH) is similar in size to vertebrate dystrophin.” Journal of Cell Biology 111, no. 5 (January 1, 1990): 1849–58. https://doi.org/10.1083/jcb.111.5.1849.Full Text
-
Kiehart, D. P., A. Ketchum, P. Young, D. Lutz, M. R. Alfenito, X. J. Chang, M. Awobuluyi, T. C. Pesacreta, S. Inoué, and C. T. Stewart. “Contractile proteins in Drosophila development.” Annals of the New York Academy of Sciences 582 (January 1990): 233–51. https://doi.org/10.1111/j.1749-6632.1990.tb21683.x.Full Text
-
Pesacreta, T. C., T. J. Byers, R. Dubreuil, D. P. Kiehart, and D. Branton. “Drosophila spectrin: the membrane skeleton during embryogenesis.” The Journal of Cell Biology 108, no. 5 (May 1989): 1697–1709. https://doi.org/10.1083/jcb.108.5.1697.Full Text
-
Kiehart, D. P., M. S. Lutz, D. Chan, A. S. Ketchum, R. A. Laymon, B. Nguyen, and L. S. Goldstein. “Identification of the gene for fly non-muscle myosin heavy chain: Drosophila myosin heavy chains are encoded by a gene family.” The Embo Journal 8, no. 3 (March 1989): 913–22. https://doi.org/10.1002/j.1460-2075.1989.tb03452.x.Full Text
-
Byers, T. J., R. Dubreuil, D. Branton, D. P. Kiehart, and L. S. Goldstein. “Drosophila spectrin. II. Conserved features of the alpha-subunit are revealed by analysis of cDNA clones and fusion proteins.” The Journal of Cell Biology 105, no. 5 (November 1987): 2103–10. https://doi.org/10.1083/jcb.105.5.2103.Full Text
-
Dubreuil, R., T. J. Byers, D. Branton, L. S. Goldstein, and D. P. Kiehart. “Drosophilia spectrin. I. Characterization of the purified protein.” The Journal of Cell Biology 105, no. 5 (November 1987): 2095–2102. https://doi.org/10.1083/jcb.105.5.2095.Full Text
-
Hagen, S. J., D. P. Kiehart, D. A. Kaiser, and T. D. Pollard. “Characterization of monoclonal antibodies to Acanthamoeba myosin-I that cross-react with both myosin-II and low molecular mass nuclear proteins.” The Journal of Cell Biology 103, no. 6 Pt 1 (December 1986): 2121–28. https://doi.org/10.1083/jcb.103.6.2121.Full Text
-
Hagen, S. J., D. P. Kiehart, D. A. Kaiser, and T. D. Pollard. “Characterization of monoclonal antibodies to acanthamoeba myosin-I that cross-react with both myosin-II and low molecular mass nuclear proteins.” Journal of Cell Biology 103, no. 6 (December 1, 1986): 2121–28. https://doi.org/10.1083/jcb.103.6.2121.Full Text
-
Kiehart, D. P., and R. Feghali. “Cytoplasmic myosin from Drosophila melanogaster.” The Journal of Cell Biology 103, no. 4 (October 1986): 1517–25. https://doi.org/10.1083/jcb.103.4.1517.Full Text
-
Kiehart, D. P., D. A. Kaiser, and T. D. Pollard. “Antibody inhibitors of nonmuscle myosin function and assembly.” Methods in Enzymology 134 (January 1986): 423–53. https://doi.org/10.1016/0076-6879(86)34109-0.Full Text
-
Wong, A. J., D. P. Kiehart, and T. D. Pollard. “Myosin from human erythrocytes.” The Journal of Biological Chemistry 260, no. 1 (January 1985): 46–49. https://doi.org/10.1016/s0021-9258(18)89689-2.Full Text
-
Eisen, A., D. P. Kiehart, S. J. Wieland, and G. T. Reynolds. “Temporal sequence and spatial distribution of early events of fertilization in single sea urchin eggs.” The Journal of Cell Biology 99, no. 5 (November 1984): 1647–54. https://doi.org/10.1083/jcb.99.5.1647.Full Text
-
Kiehart, D. P., D. A. Kaiser, and T. D. Pollard. “Direct localization of monoclonal antibody-binding sites on Acanthamoeba myosin-II and inhibition of filament formation by antibodies that bind to specific sites on the myosin-II tail.” The Journal of Cell Biology 99, no. 3 (September 1984): 1015–23. https://doi.org/10.1083/jcb.99.3.1015.Full Text
-
Kiehart, D. P., D. A. Kaiser, and T. D. Pollard. “Monoclonal antibodies demonstrate limited structural homology between myosin isozymes from Acanthamoeba.” The Journal of Cell Biology 99, no. 3 (September 1984): 1002–14. https://doi.org/10.1083/jcb.99.3.1002.Full Text
-
Kiehart, D. P., and T. D. Pollard. “Inhibition of acanthamoeba actomyosin-II ATPase activity and mechanochemical function by specific monoclonal antibodies.” The Journal of Cell Biology 99, no. 3 (September 1984): 1024–33. https://doi.org/10.1083/jcb.99.3.1024.Full Text
-
Kiehart, D. P., and T. D. Pollard. “Stimulation of Acanthamoeba actomyosin ATPase activity by myosin-II polymerization.” Nature 308, no. 5962 (April 1984): 864–66. https://doi.org/10.1038/308864a0.Full Text
-
Pollard, T. D., U. Aebi, J. A. Cooper, W. E. Fowler, D. P. Kiehart, P. R. Smith, and P. C. Tseng. “Actin and myosin function in acanthamoeba.” Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 299, no. 1095 (November 1982): 237–45. https://doi.org/10.1098/rstb.1982.0129.Full Text
-
Kiehart, D. P., I. Mabuchi, and S. Inoué. “Evidence that myosin does not contribute to force production in chromosome movement.” The Journal of Cell Biology 94, no. 1 (July 1982): 165–78. https://doi.org/10.1083/jcb.94.1.165.Full Text
-
Kiehart, D. P. “Microinjection of echinoderm eggs: apparatus and procedures.” Methods in Cell Biology 25 Pt B (January 1982): 13–31. https://doi.org/10.1016/s0091-679x(08)61418-1.Full Text
-
Kiehart, D. P. “Studies on the in vivo sensitivity of spindle microtubules to calcium ions and evidence for a vesicular calcium-sequestering system.” The Journal of Cell Biology 88, no. 3 (March 1981): 604–17. https://doi.org/10.1083/jcb.88.3.604.Full Text
-
Tilney, L. G., D. P. Kiehart, C. Sardet, and M. Tilney. “Polymerization of actin. IV. Role of Ca++ and H+ in the assembly of actin and in membrane fusion in the acrosomal reaction of echinoderm sperm.” The Journal of Cell Biology 77, no. 2 (May 1978): 536–50. https://doi.org/10.1083/jcb.77.2.536.Full Text
-
Inoué, S., G. G. Borisy, and D. P. Kiehart. “Growth and lability of Chaetopterus oocyte mitotic spindles isolated in the presence of porcine brain tubulin.” The Journal of Cell Biology 62, no. 1 (July 1974): 175–84. https://doi.org/10.1083/jcb.62.1.175.Full Text
-
-
Book Sections
-
Kiehart, D. P., Y. Tokutake, M. S. Chang, M. S. Hutson, J. Wiemann, X. G. Peralta, Y. Toyama, A. R. Wells, A. Rodriguez, and G. S. Edwards. “Ultraviolet laser microbeam for dissection of drosophila embryos.” In Cell Biology: A Laboratory Handbook, 87–103, 2005. https://doi.org/10.1016/B978-012164730-8/50137-4.Full Text
-
-
- Teaching & Mentoring
-
Recent Courses
- BIOLOGY 433S: The Biology Nobels 2023
- BIOLOGY 493: Research Independent Study 2023
- BIOLOGY 792: Research 2023
- UPGEN 716S: Genetics Student Research 2023
- BIOLOGY 293: Research Independent Study 2022
- BIOLOGY 424S: The Biological, Chemical, and Physical Bases of Cell Shape and Cell Shape Changes 2022
- BIOLOGY 493: Research Independent Study 2022
- BIOLOGY 791T: Tutorial 2022
- BIOLOGY 792: Research 2022
- UPGEN 716S: Genetics Student Research 2022
- BIOLOGY 293: Research Independent Study 2021
- BIOLOGY 424S: The Biological, Chemical, and Physical Bases of Cell Shape and Cell Shape Changes 2021
- BIOLOGY 493: Research Independent Study 2021
- BIOLOGY 791T: Tutorial 2021
- Scholarly, Clinical, & Service Activities
-
Presentations & Appearances
- High and Super-Resolution Studies of Cell Sheet Morphogenesis. Shinya Inoué Lecture at the Marine Biological Laboratory’s Analytical and Quantitative Light Microscopy Course. Analytical and Quantitative Light Microscopy Course, Marine Biological Laboratory. May 7, 2020 2020
- Biophysical and Genetic Studies of Cell Sheet Morphogenesis: Dorsal Closure as a Model System . Department of Physics Seminar Series. Rice University. April 21, 2020 2020
- Invited Speaker: Declined because of teaching obligations. September 6, 2012 2012
- Contractility and morphogenesis: Dorsal closure in Drosophila. August 10, 2012 2012
- Dorsal closure in Drosophila as a model for investigating the coordination of contractility and morphogenesis. July 26, 2012 2012
- Multidisciplinary Approaches to Morphogenesis: Powering Cell Sheet Movements During Dorsal Closure in Drosophila. April 19, 2012 2012
- Multidisciplinary Approaches to Morphogenesis: Powering Cell Sheet Movements During Dorsal Closure in Drosophila. March 15, 2012 2012
- Future Advances in Drosophila Research: Imaging. March 7, 2012 2012
- CIT Workshop Talk on Biology Gateways. April 29, 2011 2011
- Forces for Morphogenesis: Dorsal Closure as a Model System. March 24, 2011 2011
- Biophysical Contributions to Development in a Post Genomic World:_x000B_Morphogenesis, Development’s Final Frontier. February 9, 2011 2011
- Forces and Regulation for Cell Sheet Movements in Dorsal Closure. September 29, 2010 2010
- Coordinating Morphogenesis: Fly as a Model System. June 1, 2010 2010
- Coordinating Morphogenesis: Fly as a Model. April 14, 2010 2010
- Closing a Hole: Biophysical, Genetic and Pharmacological Analysis of Cell Sheet Morphogenesis. May 28, 2009 2009
- Closing a Hole: Biophysical, Genetic and Pharmacological Analysis of Cell Sheet Morphogenesis. May 24, 2009 2009
- Closing a Hole: Biophysical, Genetic and Pharmacological Analysis of Cell Sheet Morphogenesis. February 2, 2009 2009
- A Myosin Motor Powers Dorsal Closure. January 16, 2009 2009
- The Biophysics and Genetics of Molecular Motors for Morphogenesis and Sensory Perception. May 20, 2008 2008
- Biophysics of Tissue Morphogenesis: Genetic, Molecular Genetic and Pharmacological Investigation of Drosophila Dorsal Closure. May 6, 2008 2008
- Biophysical, Genetic and Pharmacological Analysis of Morphogenesis: Dorsal Closure as a Model System. April 22, 2008 2008
-
Outreach & Engaged Scholarship
-
Service to the Profession
- Member, NIH Study Panel for MIRA Awards. National Institutes of Health, Center for Scientific Review. November 9, 2020 - November 10, 2020 2020
- Nuclear Educator Orientatioin Visit to Aircraft Carrier Theodore Roosevelt at sea off the coast of California. U.S. Navy. July 8, 2019 - July 11, 2019 2019
- Dean's Trip to Asia (Beijing, Kunshan, Shanghai, Hong Kong and Singapore. Trinity College of Arts and Sciences. June 11, 2019 - June 22, 2019 2019
- Member, Special Review Committee for NIGMS Glue Grant -- Cell Migration Consortium. December 6, 2008 2008
- Ad Hoc Reviewer for professional journals. 2008 2008
-
Service to Duke
Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.