Scholars@Duke
Donald Patrick McDonnell

Donald Patrick McDonnell

Glaxo-Wellcome Distinguished Professor of Molecular Cancer Biology, in the School of Medicine
Pharmacology & Cancer Biology
donald.mcdonnell@duke.edu
Duke Box 3813, Durham, NC 27710
2138 MSRB3, 3 Genome Ct., Durham, NC 27710

Keywords

Calcium Enzyme Activation Mammary Glands, Human Cardiovascular System Proteins HEK293 Cells Antigens, Nuclear Gene Library Reactive Oxygen Species Biological Transport Biomimetic Materials Immunohistochemistry Species Specificity Phenols Organ Size Young Adult Benzhydryl Compounds Tight Junctions Diethylstilbestrol 3T3 Cells Middle Aged Extracellular Matrix Lipofuscin Lipoproteins, LDL Microscopy, Electron Pigment Epithelium of Eye Aging Bruch Membrane Adolescent Child Adult Estrenes Leupeptins Insulin-Like Growth Factor I Calcium-Calmodulin-Dependent Protein Kinase Kinase Drug Partial Agonism Protein Kinases Nuclear Receptor Coactivators Vascular Endothelial Growth Factor A Acetates Gonadal Steroid Hormones Immunosuppressive Agents Peroxidase Tumor Burden Aromatase Antineoplastic Agents, Hormonal Receptor, erbB-2 T-Lymphocytes Receptor, IGF Type 1 Inflammatory Breast Neoplasms Interleukin-1beta beta Catenin NF-kappa B MSX1 Transcription Factor Translocation, Genetic Progesterone RNA Interference Cholesterol Side-Chain Cleavage Enzyme HCT116 Cells Hepatocyte Nuclear Factor 4 Steroid 17-alpha-Hydroxylase Green Fluorescent Proteins Rats, Wistar Dehydroepiandrosterone Cluster Analysis Autocrine Communication Cadherins Protein Structure, Secondary Heat-Shock Proteins Furylfuramide Estradiol Antagonists Transcription Factor AP-1 Combinatorial Chemistry Techniques Prostate-Specific Antigen Haplorhini ADP-ribosyl Cyclase 1 Estriol Estradiol Congeners Retinoid X Receptors Mice, Inbred NOD Retinoids Mice, SCID Receptors, Retinoic Acid Chromans Retinal Dehydrogenase Induced Pluripotent Stem Cells Mice, Nude Mice, Transgenic Macular Degeneration Homeodomain Proteins Locus Coeruleus Antigens, CD Retinal Pigment Epithelium Norepinephrine Hematopoiesis Chrysenes Polymerase Chain Reaction Immunoblotting Mice, Inbred BALB C Osteogenesis Age Factors Atlases as Topic Orphan Nuclear Receptors Progestins E2F1 Transcription Factor Cholestanetriol 26-Monooxygenase Promegestone Retinoblastoma Protein Genes, Reporter Plicamycin Steroid Hydroxylases Receptors, Steroid Tacrolimus Binding Proteins MCF-7 Cells Mitogen-Activated Protein Kinases Mice, Knockout Androgens Gene Expression Regulation, Neoplastic Drug Resistance, Neoplasm Receptors, Aryl Hydrocarbon Receptors, CXCR4 Kruppel-Like Transcription Factors Aryl Hydrocarbon Receptor Nuclear Translocator Osteoclasts Chemokine CXCL12 RNA, Messenger Apoptosis Glucose Transporter Type 1 Hexokinase Acetyl Coenzyme A Multiple Myeloma Androgen Receptor Antagonists Oxidation-Reduction Up-Regulation Down-Regulation Glucose Receptors, Androgen Male Benzoates Protein Kinase Inhibitors Flow Cytometry Metribolone Prostatic Neoplasms Protein-Serine-Threonine Kinases Histone Deacetylase Inhibitors Reverse Transcriptase Polymerase Chain Reaction Estrone Mitochondria Hydroxymethylglutaryl-CoA Synthase PPAR gamma Promoter Regions, Genetic Blotting, Western Hydroxycholesterols Estrogen Replacement Therapy Retinoid X Receptor alpha Receptors, Calcitriol COS Cells Peroxisome Proliferator-Activated Receptors Cell Nucleus Selective Estrogen Receptor Modulators Thiazolidinediones Acetyltransferases Chromatin Protein Structure, Tertiary Repetitive Sequences, Nucleic Acid Enhancer Elements, Genetic RNA-Binding Proteins Consensus Sequence Recombinant Fusion Proteins Histone Acetyltransferases Carcinoma, Hepatocellular Enzyme-Linked Immunosorbent Assay Nuclear Receptor Coactivator 1 Repressor Proteins Nuclear Receptor Coactivator 2 Mutagenesis, Site-Directed Allosteric Regulation Sequence Deletion Transcription, Genetic Response Elements 8-Bromo Cyclic Adenosine Monophosphate Toxaphene Mifepristone Ovariectomy Rats Uterus Dieldrin Estrogens, Non-Steroidal Rats, Sprague-Dawley Insecticides Nuclear Receptor Co-Repressor 1 Drug Synergism Nuclear Receptor Co-Repressor 2 Drug Interactions Osteoporosis Female Saccharomyces cerevisiae Ubiquitin-Protein Ligase Complexes Saccharomyces cerevisiae Proteins Estrogens Receptors, Progesterone Receptors, Glucocorticoid Ubiquitin-Protein Ligases Raloxifene Hydrochloride Two-Hybrid System Techniques DNA Primers Transfection Cercopithecus aethiops Tamoxifen Transcriptional Activation Trans-Activators Estrogen Receptor beta Ligands Amino Acid Motifs Receptors, Estrogen Mice, Inbred C57BL Mice RNA, Small Interfering Stem Cell Transplantation Tretinoin Mice, Congenic Humans Antineoplastic Agents Estrogen Receptor alpha Stilbenes Cinnamates Aldehyde Dehydrogenase Protein Conformation Cytoprotection Enzyme Inhibitors Cell Proliferation Estradiol Estrogen Antagonists Binding Sites Amino Acid Sequence Cell Line, Tumor Molecular Sequence Data Protein Stability Indoles Proteolysis Dose-Response Relationship, Drug Breast Neoplasms Bone and Bones Chromatin Immunoprecipitation Drug Design Steroids Drug Resistance Wnt Proteins Drug Discovery Osteoblasts Molecular Targeted Therapy Receptor Cross-Talk Cholesterol Gene Expression Profiling Molecular Conformation Drug Evaluation, Preclinical Macrophages Drug Screening Assays, Antitumor Peptide Library Intracellular Signaling Peptides and Proteins Breast Estrogen Receptor Modulators Receptors, Cytoplasmic and Nuclear HeLa Cells Hormone Antagonists Transcription Factors Gene Expression DNA-Binding Proteins Gene Expression Regulation Structure-Activity Relationship Recombinant Proteins