Skip to main content

Eduardo Chaparro

Research Scholar
Neurosurgery
MSRB1 283, Durham, NC 27701
203 Research Dr., MSRB1 - 285, Durham, NC 27701

Overview


Dr. Chaparro earned his Medical Doctorate from Javeriana University in Bogotá, Colombia, and his Ph.D. in Medical Sciences with a specialization in Physiology, Pharmacology, and Neuroscience from the University of South Florida (USF) in Tampa, Florida. During his graduate studies at USF’s Anesthesiology Department, he investigated the effects of anesthetics and anti-apoptotic compounds on brain ischemia.

Following the completion of his Ph.D., Dr. Chaparro pursued post-doctoral training at Duke University’s Multidisciplinary Neuroprotection Laboratory. Here, he focused on testing drugs and devices in various animal models of neurological conditions. His work received special recognition for the successful testing of the first hepatocyte growth factor mimetic in an animal model of transient cerebral ischemia. Additionally, he successfully tested an FDA-approved vestibular stimulator for human use.

Dr. Chaparro then joined the Cerebrovascular and Skull Base Division at Duke University’s Department of Neurosurgery. His research has been dedicated to developing treatments for neurovascular conditions such as stroke, moyamoya disease, aneurysms, intracerebral hemorrhages, intravascular stent thrombogenicity, traumatic brain injury, and epilepsy. He currently serves as the Director of the Neurovascular Laboratory.

An entrepreneur at heart, Dr. Chaparro’s interest in hypothermia as a treatment for neuronal inflammation led him to patent a brain-cooling device, which has been successfully tested in non-human primates. He founded Neurocool, a startup aimed at further developing this prototype. As Medical Director, he is working towards FDA approval and the development of a human-compatible device to aid patients with central nervous system inflammatory conditions.

Current Appointments & Affiliations


Research Scholar Neurosurgery, Neurosurgery

Recent Publications


Endovascular middle cerebral artery embolic stroke model: a novel approach.

Journal Article J Neurointerv Surg · April 2022 A video (video 1) describing a novel murine endovascular embolic stroke model is presented. Traditional middle cerebral artery (MCA) occlusion models include a blind insertion of a monofilament string1 2 into the common or external carotid artery with the ... Full text Open Access Link to item Cite

Time-varying caloric vestibular stimulation for the treatment of neurodegenerative disease.

Journal Article Frontiers in aging neuroscience · January 2022 Time-varying caloric vestibular stimulation (tvCVS) is a new form of non-invasive neuromodulation similar to, but different from, diagnostic caloric vestibular stimulation (CVS). Using a non-invasive, solid-state delivery device, tvCVS has been successfull ... Full text Open Access Cite

Thromboembolic Events with Enterprise Versus Pipeline: Porcine In Vivo Experiment.

Journal Article World Neurosurg · February 2019 BACKGROUND: Thromboembolic complications are serious adverse events associated with stenting of intracranial aneurysms. For the development of novel devices, currently no practical model exists to evaluate distal embolic events. The purpose of the current ... Full text Link to item Cite
View All Publications

Recent Grants


BREEZE: New Ventricular Direct Cooling Stylet to Mitigate Secondary Brain Injury

ResearchPostdoc Scholar · Awarded by National Institutes of Health · 2022 - 2025

15-PGDH as a better therapeutic target than aspirin in decreasing risk of intracranial aneurysm rupture in men and women equally

ResearchResearch Associate · Awarded by National Institutes of Health · 2022 - 2024

Pharmacologic Suppression of Reperfusion Injury Following Endovascular Thrombectomy In Stroke

ResearchResearcher · Awarded by BioMimetix JV LLC · 2019 - 2021

View All Grants