Current Appointments & Affiliations
Lecturer of Biology
·
2024 - Present
Biology,
Trinity College of Arts & Sciences
Recent Publications
Suppression of spastin Mutant Phenotypes by Pak3 Loss Implicates a Role for Reactive Glia in AD-HSP.
Journal Article Frontiers in neuroscience · January 2020 Featured Publication Neurodegenerative mechanisms due to mutations in spastin currently center on neuronal defects, primarily in microtubule and endomembrane regulation. Spastin loss in Drosophila larvae compromises neuronal microtubule distribution, alters synap ... Full text CiteQuantitative expression of MMPs 2, 9, 14, and collagen IV in LCIS and paired normal breast tissue
Journal Article Scientific Reports · September 17, 2019 AbstractCertain matrix metalloproteinases (MMPs) have the ability to degrade collagen IV, a main component of the breast lobular basement membrane. In this cross-sectional study, we evaluated expression of MMPs 2, 9, and 14 ... Full text CiteDrosophila Models of Hereditary Spastic Paraplegia
Chapter · January 1, 2015 Hereditary spastic paraplegia (HSP) is a debilitating movement disorder with no prevention, no cure, and few options for symptom management. Rapid and relevant information is required, and the model organism Drosophila melanogaster can contribute significa ... Full text CiteRecent Grants
Genetic Analysis of the Function and Regulation of Microtubule Severing in Neurons
ResearchResearch Associate · Awarded by National Institutes of Health · 2008 - 2012View All Grants
Education, Training & Certifications
University of Virginia ·
2006
Ph.D.