ConferenceICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings · May 18, 2016
We consider the problem of recognizing objects in collections of art works, in view of automatically labeling, searching and organizing databases of art works. To avoid manually labelling objects, we introduce a framework for transferring a convolutional n ...
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ConferenceProceedings of the International Conference on Information Visualisation · December 1, 2013
Multidimensional data impose a challenge for visual analyses. Commonly, dimensionality reduction techniques are used to project the multidimensional data into a 2D visual space. Poco et al. [9] showed that projection into a 3D visual space can increase the ...
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Journal ArticleBull Math Biol · January 2013
A long-standing paradigm in B cell immunology is that effective somatic hypermutation and affinity maturation require cycling between the dark zone and light zone of the germinal center. The cyclic re-entry hypothesis was first proposed based on considerat ...
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Journal ArticleVAST 10 - IEEE Conference on Visual Analytics Science and Technology 2010, Proceedings · December 1, 2010
Geometric Wavelets is a new multi-scale data representation technique which is useful for a variety of applications such as data compression, interpretation and anomaly detection. We have developed an interactive visualization with multiple linked views to ...
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Journal ArticleSIAM Review · September 1, 2008
We illustrate the problems that can arise in writing differential equations that include Dirac delta functions to model equations with state-dependent impulsive forcing. Specifically, difficulties arise in the interpretation of the products of distribution ...
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Journal ArticleNeuron · December 2005
Proper growth of dendrites is critical to the formation of neuronal circuits, but the cellular machinery that directs the addition of membrane components to generate dendritic architecture remains obscure. Here, we demonstrate that post-Golgi membrane traf ...
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Journal ArticlePhysical review. E, Statistical, nonlinear, and soft matter physics · February 2004
We demonstrate here the implementation of an experimental system suitable for the study of the diffusion limited A+B-->0, nonclassical reaction behavior. Using a combination of a fluorescent calcium indicator and a calcium ion which is initially "caged," a ...
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Journal ArticleJournal of biomedical materials research. Part A · September 2003
Monodisperse, spherical, polyethylene glycol (PEG)-coated silica nanoparticles have been prepared at room temperature and characterized for the purpose of biomedical applications. The particles were synthesized by the hydrolysis of tetramethyl orthosilicat ...
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ConferenceSensors and Actuators, B: Chemical · April 20, 2003
Polyacrylamide (PAA) and amine-functionalized PAA (AFPAA) nanoparticles with disulfonated 4,7-diphenyl-1,10-phenantroline ruthenium (Ru(dpp(SO3)2)3) have been prepared. The nanoparticles produced have a hydrodynamic radius of 20-25 nm. The amount of single ...
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Journal ArticleThe Analyst · January 2002
The development and characterisation of a fluorescent optical PEBBLE (Probe Encapsulated By Biologically Localised Embedding) nanosensor for the detection of zinc is detailed. A ratiometric sensor has been fabricated that incorporates two fluorescent dyes; ...
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ConferenceProceedings of SPIE - The International Society for Optical Engineering · January 1, 2002
In this study we show that steady-state fluorescence anisotropy within PEBBLEs (Probes Encapsulated By Biologically Localized Embedding) can be used for the optochemical sensing of analytes such as Zn2+, O2, and Ca2+. Steady-state fluorescence anisotropy i ...
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ConferenceProceedings of SPIE - The International Society for Optical Engineering · January 1, 2002
Monodisperse, spherical, polyethylene glycol (PEG)-coated silica nanoparticles have been prepared in the size range of 50-350 nm, and their size and size distribution were characterized by SEM and multi-angle static light scattering experiments. The chemic ...
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Journal ArticlePhysical review letters · July 2000
An experimental demonstration is provided for memory-based, nonclassical reaction kinetics in a homogeneous system with an elementary reaction, A+B-->C. A new reaction-kinetics regime is observed which is a direct consequence of speckles in the laser beam. ...
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ConferenceMaterials Research Society Symposium - Proceedings · January 1, 1999
We demonstrate here the implementation of an experimental system suitable for the study of the diffusion-limited A+B→0, non-classical reaction behavior. Using a combination of a fluorescent calcium indicator and a calcium ion which is initially 'caged', a ...
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ConferenceSensors and Actuators, B: Chemical · August 31, 1998
Described here are arguably the world's smallest stand-alone devices/sensors, consisting of multicomponent nano-spheres with radii as small as 10 nm, occupying ≈1 ppb of a typical mammalian cell's volume. The probe is prepared from up to seven ingredients ...
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ConferenceUltramicroscopy · March 1, 1998
We present a recently constructed near-field scanning optical microscope which incorporates improvements over our previous designs. This microscope features an ultra-fine mechanical tip/sample approach with continuous submicron control over a range of seve ...
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Journal ArticleReview of Scientific Instruments · January 1, 1998
We present a transmission, fluorescence, and polarization near-field scanning optical microscope with shear-force feedback control that is small in size and simple to operate. This microscope features an ultrafine mechanical tip/sample approach with contin ...
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Journal ArticlePhysical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics · January 1, 1997
A focused laser beam acts as both a “phototrap”, bleaching fluorophore molecules that diffuse into the beam path, and as a confocal probe, detecting the excited, unbleached fluorophore molecules still present in the trap. With this focused laser beam, we o ...
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ConferenceMaterials Research Society Symposium - Proceedings · January 1, 1997
A focused laser beam acts as both a `phototrap', bleaching fluorophore molecules which diffuse into the beam path, and as a confocal probe, detecting the excited, unbleached fluorophore molecules still present in the trap. With this focused laser beam, we ...
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Journal ArticleAnalytical chemistry · November 1996
The major concern with optodes, especially miniaturized ones, has been their photobleaching limited lifetime. Liquid polymer [highly plasticized poly(vinyl chloride)] films are commonly used to prepare fluorescent optical fiber sensors. A major advantage i ...
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Journal ArticleUltramicroscopy · February 1995
We describe our progress toward an NSOM system intended for fluorescence imaging of biological samples. This process included integration of shear-force feedback into an existing NSOM system. Topographic images acquired using uncoated tips are presented. W ...
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ConferenceProceedings of SPIE - The International Society for Optical Engineering · June 4, 1993
Biological samples, molecular solids and solid state devices have been investigated by Near-Field Scanning Optical Microscopy (NSOM), Near-Field Optical Spectroscopy, and Near-Field Chemical Sensing. We report here on our progress in applying the NSOM tech ...
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